Targeted Drug Delivery using Porous Glass Microspheres
Finding ways to improve efficiency and bioavailability is key to targeted drug delivery. Although controlled release dosage medication forms are the standard, they can have certain limitations.... read more
Risk of hemorrhage with statins and stroke prevention drug combination
Two commonly used statins can increase the risk of hemorrhage when combined with dabigatran etexilate, a drug often used for preventing stroke in patients with atrial fibrillation.... read more
Recruitment manoeuvres for adults with acute respiratory distress syndrome receiving mechanical ventilation
Ten trials met the inclusion criteria for this review (n = 1658 participants). We found five trials to be at low risk of bias and five to be at moderate risk of bias.... read more
Coma with Eelco Wijdicks – Podcast
So you have an unresponsive patient. The CT is negative. What now? Coma is tough! The differential is long and filled with many life threats.... read more
Acute Flaccid Myelitis Outbreak in Washington
There has been a recent spike of cases reported in five counties in Washington State, in which eight children have been hospitalized for Acute Flaccid Myelitis.... read more
What a hospital bed could teach about patient safety
Most hospitalized patients spend the vast majority of their time in a hospital bed. Any body fluids such as blood, feces, urine, stomach contents, etc. that are secreted come in direct contact with that hospital bed.... read more
Negative pressure irrigation and endoscopic necrosectomy through man-made sinus tract in infected necrotizing pancreatitis
This four-step approach is effective in treating IPN and adds no extra risk to patients when compared with other latest step-up strategies. The two novel techniques (NPI and ED) could offer distinct clinical benefits without... read more
Children in ICU recover faster without nutrition
Researchers in Belgium found the standard practice of feeding children as soon as they get to ICU to help them recover faster is wrong.... read more
Vasopressin vs. norepinephrine for vasoplegic shock after cardiac surgery
Patients in the VANISH trial treated with vasopressin had a lower incidence of renal failure requiring hemodialysis. However, this was a secondary endpoint which seemed to contradict the primary endpoint (defined as a milder... read more
HSCI researchers use color tagging system to track development of blood stem cells
Harvard Stem Cell Institute (HSCI) researchers have used a colorful, cell-labeling technique to track the development of the blood system and trace the lineage of adult blood cells travelling through the vast networks of... read more
Mount Sinai Researchers Use Computer Algorithms to Diagnose HCM
Computer algorithms can automatically interpret echocardiographic images and distinguish between pathological hypertrophic cardiomyopathy (HCM) and physiological changes in athletes' hearts.... read more
VIB scientists discover neuron-producing stem cells in the membranes covering the brain
In a cross-domain study directed by professor Peter Carmeliet (VIB - KU Leuven), researchers discovered unexpected cells in the protective membranes that enclose the brain, the so called meninges.... read more
Lean six methodology can cut health care-linked infections
Application of the Lean Six Sigma (LSS) methodology can reduce the risk of health care-associated infections (HAI) among patients undergoing surgical procedures.... read more
Beta-blocker Therapy Seems to Boost Post-PCI Outcomes in Patients With ACS
Guidelines from the American College of Cardiology and American Heart Association recommend using beta-blockers in patients with STEMI and NSTEMI, although studies looking at the effects of treatment have provided somewhat... read more
Study Examines Rates, Causes of ED Visits for Adverse Drug Events
The prevalence of emergency department (ED) visits for adverse drug events (ADEs) in the United States was estimated to be four per 1,000 individuals in 2013 and 2014, and the most common drug classes involved were anticoagulants,... read more
Devil in the details: Endotracheal tube depth
According to Napoleon, "the moment of greatest vulnerability is the instant immediately after victory." In airway management, this instant occurs immediately after placement of the endotracheal tube.... read more
Diabetes monitoring breathalyzer developed
A new hand-held breathalyzer that allows individuals to easily assess their blood glucose levels has been developed. The device informs the user bout diabetes risk and it differs from a medical device we reported on earlier... read more
