Traumatic Major Hemorrhage in a Tertiary Trauma Center
Major traumatic hemorrhage is potentially preventable with rapid hemorrhage control and improved resuscitation techniques. The time from injury to hospital, resuscitation, diagnosis, and definitive bleeding control should... read more
Scientific Study Validates Usability of Post-ICU Digital Diary for Families of ICU Patients
In a groundbreaking pilot study, "The usability of a digital diary from the perspectives of intensive care patients’ relatives", researchers have unequivocally confirmed the practicality and effectiveness of Post-ICU for... read more
AKI Risk Factors in ICU Patients Using Colistin
Colistin, an antibiotic of polymyxin group, has recently been increasingly used in the treatment of multidrug resistant gram-negative bacteria. However, it has serious adverse effects such as acute kidney injury (AKI). We... read more
Anticipating the Future of the COVID-19 Pandemic
The initial instance of a severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection was observed in December 2019 in the city of Wuhan, China. Subsequently, the virus disseminated expeditiously across the globe,... read more
COVID-19 Airway Management and Ventilation Strategy for Critically Ill Older Patients
This book describes the issues and challenges that clinicians encountered in the management of older critically ill patients during the COVID-19 pandemic, and offers practical information on how to manage them. Older... read more
VTE in Critically Ill Adult Patients with Hematologic Malignancy
Among patients with hematologic malignancy, critical illness and certain baseline characteristics were associated with a higher incidence of venous thromboembolism (VTE). Among 76,803 eligible patients (mean age 67 years... read more
Omadacycline Treatment of Severe Pneumonia Complicated with ARDS During COVID-19
Metagenomic next-generation sequencing (mNGS) has a significant value in the diagnosis of Chlamydia psittaci infection. Timely treatment of omadacycline can improve prognosis and provide a promising new option for the treatment... read more
Clinical Outcomes in Critically Ill COVID-19 Unvaccinated Patients Admitted to the ICU
We analyzed unvaccinated critically ill ICU patients with COVID-19 and interpreted their demographics, clinical characteristics, comorbidities, and laboratory data upon ICU admission for a better understanding of their impact... read more
Haloperidol vs. Placebo in ICU Patients with Delirium
We assessed long-term outcomes in acutely admitted adult patients with delirium treated in intensive care unit (ICU) with haloperidol versus placebo. In acutely admitted adult ICU patients with delirium, haloperidol treatment... read more
10 Reasons for Pharmacy Professionals Presence in the ICU
The momentum exists for establishing and expanding ICU pharmacy practice throughout Europe. A first step should be a White Paper, describing the roles and key priorities for ICU pharmacy professionals. Education should... read more
Critical Hypertension in Trauma Patients Following Prehospital Emergency Anesthesia
Delivery of prehospital emergency anesthesia (PHEA) to seriously injured trauma patients risks hemodynamic fluctuation. In adult trauma patients undergoing PHEA, 11.9% of patients experienced post-PHEA critical hypertension.... read more
EEG Patterns for Predicting Poor Outcome After Cardiac Arrest
The specificity of the ERC-ESICM-recommended EEG patterns for predicting poor outcome after cardiac arrest exceeds 90% but is lower than in previous studies, suggesting that large-scale implementation may reduce their accuracy.... read more
Critical Care: A New Nurse Faces Death, Life, and Everything in Between
Doctors heal, or try to, but as nurses we step into the breach, figure out what needs to be done for any given patient today, on this shift, and then, with love and exasperation, do it as best as we can. Critical Care... read more
Ilofotase Alfa Doesn’t Improved Survival Among Critically Ill Patients with SA-AKI
Sepsis-associated acute kidney injury (SA-AKI) in patients admitted to an intensive care unit is associated with significant morbidity and mortality. There is currently no pharmaceutical treatment. Although we found no... read more
Ineffective Airway Clearance Nursing Diagnosis & Care Plans
Ineffective airway clearance is the inability to clear secretions or obstructions from the respiratory tract. This can be detrimental to breathing and create complications. Secretions can be problematic as a result of... read more
Dyspnea and Dyspnea-Associated Anxiety in ICU Patients
Dyspnea is frequently associated with anxiety, prolonged days on mechanical ventilation, and worse quality of life after discharge. It can also increase the risk of posttraumatic stress disorder post ICU discharge. However,... read more
Heat Shock Protein 27 in COVID-19 and non-COVID ARDS Pathogenesis
Acute respiratory distress syndrome (ARDS) is a common cause of hypoxemic respiratory failure in intensive care units that has increased dramatically as a result of the COVID-19 pandemic. In both COVID-19 and non-COVID... read more
Efficacy of High-Flow Nasal Cannula Oxygen Therapy in Patients with AHRF
This study suggests that high-flow nasal cannula (HFNC) therapy in general respiratory wards may be a potential rescue therapy for patients with respiratory failure. Electrical impedance tomography (EIT) potentially monitors... read more
Intravenous Vitamin C for COVID-19 Patients
In hospitalized patients with COVID-19, vitamin C had low probability of improving the primary composite outcome of organ support–free days and hospital survival. Enrollment was terminated after statistical triggers... read more
Oxygenation Improvement in Hyperinflammatory Ovine ARDS Treated with Methylprednisolone
Early and persistent improvement in oxygenation was seen only in hyperinflammatory ovine ARDS treated with methylprednisolone, while hemodynamic situation and survival was improved in both injury models and corticosteroid... read more
Uncovering Heterogeneity in Sepsis
Among critically ill patients with sepsis, subtype strategies using clinical, biomarker, and transcriptomic data do not identify comparable patient populations and are likely to reflect disparate clinical characteristics... read more
Pediatric Sepsis Phenotype with Persistent Hypoxemia, Encephalopathy, and Shock
We derived and validated the persistent hypoxemia, encephalopathy, and shock phenotype, which is highly reproducible, clinically relevant, and associated with HTE to common adjuvant therapies in children with sepsis. We... read more
