Eosinopenia as a Predictor of Clinical Outcomes in CAP Patients
Contrary to previously published data, our analysis did not demonstrate an association between eosinopenia and increased mortality risk in hospitalized patients with community-acquired pneumonia (CAP), highlighting the complexity... read more
Vasoactive Agents in Cardiogenic Shock Related to AMI and ADHF
Cardiogenic shock (CS) is a heterogeneous condition associated with exceptionally high mortality rates, despite significant advances in the field of cardiology. The primary causes of CS are myocardial infarction-related CS... read more
Sepsis: Definitions, Pathophysiology and the Challenge of Bedside Management
A comprehensive and state-of-the-art resource for clinicians who care for patients with sepsis and research scientist alike. Patients with severe sepsis requiring ICU admission have very high rates of ICU and overall... read more
Failure to Rescue in ALF
The concept of failure to rescue has been used to measure the quality of care for complications developed following surgery. In patients with acute liver failure (ALF), the concept of failure to rescue highlights the... read more
Recent Advances in Severe Sepsis and Septic Shock Management
This review highlights recent advances in the treatment of severe sepsis and septic shock, emphasizing new strategies aimed at improving overall survival and reducing mortality in this patient population. Despite years... read more
Textbook of Neurointensive Care: Volume 1: Neuroanatomy, Diagnostic Assessment, Disease Management
This extensively updated edition provides a comprehensive review of intensive care for neurologically injured patients from the emergency room and ICU through the operating room and post-surgical period in two comprehensive... read more
Oral Health Care and VAP in ICU Patients
Both Zataria Multiflora (ZM) and Chlorhexidine (CHG) and CHG alone reduce ventilator-associated pneumonia (VAP) incidence and improve the oral health status of mechanically ventilated patients. However, the combination of... read more
Prone Position: Achieving Nutritional Goals
Critically ill patients in the prone position had longer hospital stays and higher mortality rates, while being more likely to initiate and remain on enteral nutrition for a longer period. However, no significant differences... read more
Antibiotic Pharmacokinetic/Pharmacodynamic Considerations in the Critically Ill
This book provides unique insights into the issues that drive modified dosing regimens for antibiotics in the critically ill. Leading international authors provide their commentary alongside a summary of existing evidence... read more
Nebulized Long-Acting Bronchodilators to Treat ARF in an Older Patients
Although long-acting bronchodilators are not approved to treat acute respiratory failure (ARF), the older adult in this case clinically improved after three doses of revefenacin and arformoterol. Additional studies are... read more
Different Anticoagulation Regimens Effectiveness in Critically Ill Patients
This study compared the efficacy of therapeutic anticoagulation guided by anti-Xa levels vs. a D-dimer-based protocol in ICU patients with COVID-19. Given the heightened risk of thrombosis despite anticoagulation therapy... read more
Cytokine Storm Syndrome
Cytokine Storm Syndromes, including HLH and MAS, are frequently fatal disorders, particularly if not recognized early and treated during presentation. The genetics of Cytokine Storm Syndromes are being defined with many of... read more
Awareness Strategies and the Physiological Pain Impact in Prehospital Analgesia Management
Developing awareness strategies for prehospital pain management could improve analgesic outcomes, but further research is needed to understand the physiological impact of pain on vital systems. Investigating these dynamics... read more
COPD: Heterogeneity and Personalized Treatment
This book explains how analysis of the heterogeneity of chronic obstructive pulmonary disease (COPD) enhances understanding of the condition and leads to improved, personalized treatment. State of the art knowledge is presented... read more
Methylprednisolone vs. Hydrocortisone in Septic Shock Patients
Corticosteroids play an important role in the management of septic shock patients, especially in those with higher doses of vasopressor. However, the therapeutic benefits of corticosteroids are not limited to hydrocortisone... read more
Elevated BCR Risk Factor For CHF in Critically Ill COPD Patients
Chronic obstructive pulmonary disease (COPD) is a leading cause of global morbidity and death. The blood urea nitrogen-to-creatinine ratio (BCR) is recognized as a crucial marker to assess renal function and cardiovascular... read more
ICU Protocols: A Step-wise Approach, Vol II
The second edition of this highly successful book includes up-to-date notes on the step-wise management of clinical emergencies encountered in everyday intensive care units (ICU). Each thoroughly revised chapter provides... read more
Assessing the Risk of Poor Clinical Outcomes in Preterm Neonates with Late-onset Sepsis
A predictive calculator for assessing the risk of poor clinical outcomes in preterm neonates with late-onset sepsis (LOS) has been developed. By leveraging readily available clinical data at the time of blood culture collection,... read more
Patients Under Mechanical Ventilation Are Highly Perceptive
This meta-synthesis provides insights into the perception of intensive care patients under Mechanical Ventilation (MV) who are continuously observing their own lives. This process is complex and involves a highly differentiated... read more
Hemoglobin Glycation Index vs. Adverse Outcomes in Critically Ill Patients with Myocardial Infarction
Based on the MIMIC-IV database, this study found that lower HGI is significantly associated with an increased risk of short-, mid- and long-term all-cause mortality in critically ill myocardial infarction (MI) patients. As... read more
Basic Ultrasound Skills “Head to Toe” for General Intensivists (Lessons from the ICU)
The aim of this book, part of the European Society of Intensive Care Medicine (ESICM) textbook series, is to educate and train practitioners in the safe and competent use of diagnostic ultrasound imaging in the visualization... read more
Thromboprophylaxis Preferences in the ICU
Low-molecular-weight heparin (LMWH) was the preferred agent for thromboprophylaxis in critically ill patients. There was considerable variation in the application of LMWH for prophylaxis, reflected by the use of different... read more
