The Airway Manual: Practical Approach to Airway Management
The book provides up-to-date and easy to understand information on airway management with special emphasis on practical management along with required theory background and key points. It covers all aspects of airway management... read more
Post-Hospital AKI: A Long-Term Health Hazard
A systematic review and meta-analysis of 14 matched control studies, totaling over 1 million patients, investigated the long-term outcomes following an episode of Acute Kidney Injury (AKI) during hospitalization. The... read more
Assessing Vulnerability: Frailty’s Link to ICU Infections
This study outlines the protocol and statistical analysis plan for a preplanned secondary analysis of the PROSPECT trial (Probiotics to Prevent Severe Pneumonia and Endotracheal Colonization Trial). The goal of this research... read more
Hemodynamic Monitoring in the ICU
This book describes the pathophysiological significance of the hemodynamic monitoring parameters available to the clinician and their role in providing reliable and reproducible information on the cardiocirculatory status... read more
Neuro-ICU Admissions: Lower Mortality, Higher Disability Risk
This large-scale retrospective cohort study analyzed the clinical and epidemiological profiles of over 62,000 Intensive Care Unit (ICU) patients across seven hospitals, finding that the 10,884 patients admitted for primary... read more
Survival Shockwave: VV-ECMO Outperforms VA-ECMO in Respiratory Failure
This meta-analysis comparing venovenous (VV-ECMO) and venoarterial (VA-ECMO) extracorporeal membrane oxygenation for respiratory failure, encompassing 3,598 patients across eleven studies, found a significant survival advantage... read more
Sepsis Heart Mystery: Is Myocardial Dysfunction a Killer or Just a Sign of Sickness?
Sepsis-induced myocardial dysfunction (SIMD) is a common and clinically significant complication in critically ill patients with sepsis and septic shock. This systematic review confirms that SIMD is consistently linked to... read more
Cytokine Storm Syndrome
Cytokine Storm Syndromes, including HLH and MAS, are frequently fatal disorders, particularly if not recognized early and treated during presentation. The genetics of Cytokine Storm Syndromes are being defined with many of... read more
ICU Alert: Unraveling Mortality in Obstructive Pyelonephritis
This retrospective multicenter study investigated in-hospital mortality among 483 patients admitted to the ICU (8 centers) over a decade due to obstructive pyelonephritis, a severe condition often caused by kidney stones,... read more
Seamless Surveillance: The Future of NICU Vital Sign Monitoring
A comprehensive systematic review evaluated 60 observational studies published between 2014 and 2024 to assess the potential of next-generation non-contact and wireless wearable technologies for vital sign monitoring in the... read more
Predictive Power: Wearable AI Foreshadows Hospital Deterioration
This study successfully developed and validated a deep learning-based continuous in-hospital deterioration prediction model using data collected from wearable chest-worn monitors. The researchers piloted two different Continuous... read more
BICARICU-2: Bicarb Infusions Curb Dialysis Needs in Acidotic AKI
The BICARICU-2 trial investigated the use of sodium bicarbonate (NaHCO3) infusions for critically ill patients suffering from severe acidemia and Acute Kidney Injury (AKI), most often due to septic shock. While the trial,... read more
The Falling Count: Platelet Trajectory Post-CRRT Predicts Mortality in AKI
This retrospective cohort study examined the dynamic changes in platelet counts—the platelet trajectory—around the initiation of Continuous Renal Replacement Therapy (CRRT) in over 2,200 critically ill adults with Acute... read more
Salinity Signal: Low Sodium-Chloride Difference Predicts Higher Mortality in Critically Ill Adults
This retrospective cohort study investigated the relationship between the easily calculated Sodium–Chloride Difference (SCD) at the time of ICU admission and the patient's subsequent 30-day mortality risk in 1,726 critically... read more
Mechanical Ventilation in Patient with Respiratory Failure
This handbook covers the principles of mechanical ventilation, making them easy to understand and apply in clinical settings. Presented in an accessible style and supplemented by a wealth of illustrations and graphs, it includes... read more
The Dual Deception: Amlodipine and Baclofen Overdose Mimics Brain Death and Triggers Cardiogenic Shock
This case study highlights the profound diagnostic challenge and dramatic presentation of a combined-drug overdose involving amlodipine and baclofen, a novel and previously unreported toxicological combination. Toxicological... read more
Coordinated Critical Care: Essential ICU Strategies for Severe Trauma
The effective management of severe trauma patients hinges on seamless, perfect coordination across prehospital care, the trauma bay, and the ICU. Once in the Intensive Care Unit, the primary goals are the prompt control of... read more
Handbook of Evidence-Based Critical Care
This updated and revised edition of the classic bedside pocket reference remains the gold standard in critical care medicine. The new edition maintains Dr. Marik's trademark humor and engaging writing style, while adding... read more
The Paradox of Recovery: Faster APACHE II Decline Does Not Guarantee Better Trauma Outcomes
This study investigated a novel metric, APACHE/m (the average daily decrease in the APACHE II score), to determine if a faster rate of physiological improvement predicts better post-ICU outcomes in trauma patients. While... read more
VA-ECMO in Septic Shock: A High-Stakes, High-Uncertainty Rescue
The use of Veno-Arterial Extracorporeal Membrane Oxygenation (VA-ECMO) as a rescue therapy for refractory septic shock remains a challenging, context-dependent, and uncertain strategy in adults. Current evidence shows... read more
The Vasopressor & Inotrope Handbook: A Practical Guide for Healthcare Professionals
An indispensable resource for physicians, nurse practitioners, physician assistants, pharmacists, and nurses in managing critically ill patients. This comprehensive guide delves deep into the world of vasopressors and inotropes,... read more
Vasoactive Guard: Testing Arginine-Vasopressin to Shield Kidneys Post-Liver Transplant
This clinical trial investigates whether a low dose of argipressin (the active substance in REVERPLEG) administered during liver transplantation surgery can help prevent Acute Kidney Injury (AKI), a severe and common post-operative... read more
