Pragmatic Approach to Inpatient Diabetes Management During COVID-19

Pragmatic Approach to Inpatient Diabetes Management During COVID-19

The pandemic of COVID-19 has presented new challenges to hospital personnel providing care for infected patients with diabetes who represent more than 20% of critically ill patients in ICUs. Appropriate glycemic management... read more

From Russia with Love – “Sputnik V” COVID-19 Vaccine Generated an Immune Response

From Russia with Love – “Sputnik V” COVID-19 Vaccine Generated an Immune Response

Between June 18 and Aug 3, 2020, Ministry of Health of the Russian Federation enrolled 76 participants to the two studies (38 in each study). In each study, 9 volunteers received rAd26-S in Phase 1, nine received rAd5-S in... read more

Sepsis and COVID-19: Perspectives From a Sepsis Coordinator

Sepsis and COVID-19: Perspectives From a Sepsis Coordinator

Coronavirus disease 2019 (COVID-19) has brought difficulties and disruptions to all corners of the world. As a sepsis coordinator, I can attest that the scientific and healthcare community in the United States has been particularly... read more

COVID-19: A Critical Analysis of Chloroquine and Hydroxychloroquine Clinical Pharmacology

COVID-19: A Critical Analysis of Chloroquine and Hydroxychloroquine Clinical Pharmacology

Chloroquine and hydroxychloroquine have been used for over 60 years in the treatment of malaria, amoebic liver abscess, and several rheumatological conditions, but their clinical pharmacology is not well understood. COVID-19... read more

Hydroxychloroquine With or Without Azithromycin

Hydroxychloroquine With or Without Azithromycin

Among patients hospitalized with mild-to-moderate COVID-19, the use of hydroxychloroquine, alone or with azithromycin, did not improve clinical status at 15 days as compared with standard care. A total of 667 patients... read more

Effects of Telemedicine ICU Intervention on Care Standardization and Patient Outcomes

Effects of Telemedicine ICU Intervention on Care Standardization and Patient Outcomes

In this pre-post observational study, telemedicine ICU intervention was associated with improvements in care standardization and decreases in ICU and hospital mortality and length of stay. The mortality benefits were mediated... read more

Bedside ECHO To Diagnose Native Valve Infective Endocarditis

Bedside ECHO To Diagnose Native Valve Infective Endocarditis

Infective endocarditis (IE) is an important pathology to detect in the Emergency Department (ED), but the diagnosis is too often delayed or missed. IE ticks many boxes as a diagnosis we can "own" in Emergency Medicine (EM): 1.... read more

Training Multidisciplinary Healthcare Workers to Reinforce ICUs in Times of Need

Training Multidisciplinary Healthcare Workers to Reinforce ICUs in Times of Need

ESICM is to carry out a C19 SPACE programme funded by the European Commission for the training of multidisciplinary healthcare professionals not regularly working in ICUs, to give extra support to ICUs during the COVID-19... read more

Effect of Hydrocortisone on Mortality and Organ Support in Patients with Severe COVID-19

Effect of Hydrocortisone on Mortality and Organ Support in Patients with Severe COVID-19

Among patients with severe COVID-19, treatment with a 7-day fixed-dose course of hydrocortisone or shock-dependent dosing of hydrocortisone, compared with no hydrocortisone, resulted in 93% and 80% probabilities of superiority... read more

CDC Tells States How to Prepare for Covid-19 Vaccine by Early November

CDC Tells States How to Prepare for Covid-19 Vaccine by Early November

The Centers for Disease Control and Prevention has notified public health officials in all 50 states and five large cities to prepare to distribute a coronavirus vaccine to health care workers and other high-risk groups as... read more

Survey Finds More Than Half of Pediatric Cardiology Nurses Are Burned Out

Survey Finds More Than Half of Pediatric Cardiology Nurses Are Burned Out

More than half of nurses caring for children with cardiovascular conditions are emotionally exhausted and good working environments were linked with less burnout, according to a survey presented during ESC Congress 2020. Of... read more

Steroids Confirmed to Help Severely Ill COVID-19 Patients

Steroids Confirmed to Help Severely Ill COVID-19 Patients

In patients hospitalized with COVID-19, the use of dexamethasone resulted in lower 28-day mortality among those who were receiving either invasive mechanical ventilation or oxygen alone at randomization but not among those... read more

Obesity and the Risk of Intubation or Death in Patients with COVID-19

Obesity and the Risk of Intubation or Death in Patients with COVID-19

Among consecutive patients hospitalized with coronavirus disease 2019, obesity was an independent risk factor for intubation or death. A total of 305 patients were included in this study. We stratified patients by body... read more

Bacterial Profile of Ventilator Associated Pneumonia: Concept, Review, Methods, Observations, Inference

Bacterial Profile of Ventilator Associated Pneumonia: Concept, Review, Methods, Observations, Inference

ICU is a hotbed of infections and measures are taken to prevent these infections. Ventilator associated pneumonia is one of the Intensive Care Unit related infections. This book tells us what ventilator associated pneumonia... read more

Cardiovascular and Renal Outcomes with Empagliflozin in Heart Failure

Cardiovascular and Renal Outcomes with Empagliflozin in Heart Failure

Among patients receiving recommended therapy for heart failure, those in the empagliflozin group had a lower risk of cardiovascular death or hospitalization for heart failure than those in the placebo group, regardless of... read more

Principles Guiding Non Pandemic Critical Care Research During a Pandemic

Principles Guiding Non Pandemic Critical Care Research During a Pandemic

Deliberation about continuing non pandemic research should use objective, transparent criteria considering several aspects of the research process such as bedside and research staff safety, infection control, the informed... read more

Limiting Radiation in Trauma Imaging & Trauma Resuscitation

Limiting Radiation in Trauma Imaging & Trauma Resuscitation

Appropriate clinical decision-making in the initial evaluation and management of trauma patients in the emergency department is critical to optimize patient outcomes. This supplement provides evidence-based recommendations... read more