Who Gets to Live? How Doctors Make Impossible Decisions as COVID-19 Surges

Triage aims to provide the greatest amount of good for the greatest number, but medical staff are grappling with how to stay true to this principle as coronavirus surges. 18 states are currently in what's considered the... read more

Intracerebral Hemorrhage (ICH)

Intracerebral Hemorrhage (ICH)

For most patients, the best treatment seems to be high-quality supportive care. Aggressive interventions (e.g., causing dramatic drops in blood pressure and "prophylactic" hypertonic saline) may cause more harm than good. Cerebellar... read more

A Concise Overview of Non-invasive IAP Measurement Techniques

A Concise Overview of Non-invasive IAP Measurement Techniques

This review presents an overview of previously reported non-invasive intra-abdominal pressure (IAP) measurement techniques. Each section covers the basic physical principles and methodology of the various measurement techniques,... read more

30% of COVID-19 Patients Had No Symptoms of Fever, Cough, or Shortness of Breath

30% of COVID-19 Patients Had No Symptoms of Fever, Cough, or Shortness of Breath

The findings of this cohort study suggest that screening based on conventional COVID-19 symptoms or corresponding examination findings of febrile respiratory illness may not possess the necessary sensitivity for early diagnostic... read more

Risks Of VAP in Patients With Viral ARDS Related or Not To COVID-19

Risks Of VAP in Patients With Viral ARDS Related or Not To COVID-19

In this retrospective case-control study, we have observed a higher prevalence of ventilator-associated pneumonia (VAP) and MDR VAP in C-ARDS as compared with NC-ARDS patients. Further, probably multicenter, research work... read more

Review of Viral Testing and Antibody/Serology Testing for COVID-19 for the Intensivist

Review of Viral Testing and Antibody/Serology Testing for COVID-19 for the Intensivist

The severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) (coronavirus disease 2019 [COVID-19]) pandemic has led to the rapid development of many diagnostic tests. The initial focus of these tests was on molecular... read more

COVID-19: A Hypothesis Regarding the Ventilation-Perfusion Mismatch

COVID-19: A Hypothesis Regarding the Ventilation-Perfusion Mismatch

We believe that a severe V/Q mismatch underlies the pathophysiology of moderate to severe COVID-19 cases, in which downregulation of ACE2 secondary to viral endocytosis plays a key role. There is low V/Q ratio in areas of... read more

Preventing Major Airway Complications

Preventing Major Airway Complications

Every anaesthetist fears the moment they might become faced with a "can't intubate, can't oxygenate" (CICO) scenario, but thankfully such events are exceedingly rare. They nevertheless receive much attention in the academic... read more

Bedside PUG Tube Placement by Critical Care Physicians

Bedside PUG Tube Placement by Critical Care Physicians

Critically ill patients often require gastrostomy tubes. Percutaneous endoscopic gastrostomy has become the most common method of placement but is not widely performed by critical care physicians, in part due to their lack... read more

The Application of 6S and PDCA Management Strategies in the Nursing of COVID-19 Patients

The Application of 6S and PDCA Management Strategies in the Nursing of COVID-19 Patients

Overall, the management of the nursing team followed the PDCA (Plan-Do-Check-Act) cycle management principle as described in a previous study, thus enabling real-time planning, execution, inspection and improvement. During... read more

Critical Care and Hospitalist Medicine Made Ridiculously Simple

Critical Care and Hospitalist Medicine Made Ridiculously Simple

A fundamental and thorough guide to the treatment of hospitalized patients in critical care situations, "Critical Care and Hospitalist Medicine Made Ridiculously Simple" provides both introductory information as well as a... read more

POCUS is Having Its Moment

POCUS is Having Its Moment

Ultrasound performed at the point of care (POCUS) is having its moment. The COVID-19 pandemic has seemingly caused the acceleration of POCUS acceptance by hospital leaders, and POCUS examinations are increasingly performed... read more

Factors Associated With Death in Critically Ill Patients With COVID-19 in the US

Factors Associated With Death in Critically Ill Patients With COVID-19 in the US

This study identified demographic, clinical, and hospital-level risk factors that may be associated with death in critically ill patients with COVID-19 and can facilitate the identification of medications and supportive therapies... read more

Infectious Meningitis and Encephalitis in ICU

Infectious Meningitis and Encephalitis in ICU

Infectious meningitis and encephalitis are a major concern in ICU since they are associated with high mortality and permanent neurological injury. About 3% of central nervous system infections will be admitted in the ICU. Three... read more

Moderna mRNA Vaccine Candidate’s Phase I Trial

Moderna mRNA Vaccine Candidate’s Phase I Trial

Eight weeks to the day after press-releasing some top line results, the full paper is out on the Moderna mRNA vaccine candidate’s Phase I trial. I'm very glad to see it – it's going to be very important for the full data... read more

Early Prediction of ICU-Acquired Weakness

Early Prediction of ICU-Acquired Weakness

The previously developed prediction model for ICU-AW showed poor performance in a new independent multicenter validation cohort. Model updating methods improved calibration but not discrimination. The newly derived prediction... read more

Managing COVID-19 in Hospital Settings

Managing COVID-19 in Hospital Settings

A series of papers to be published across a variety of journals provides a potential roadmap for treating COVID-19 patients within a hospital setting. It tells practitioners in these healthcare environments how to prepare... read more