Families in the Intensive Care Unit: A Guide to Understanding, Engaging, and Supporting at the Bedside

Families in the Intensive Care Unit: A Guide to Understanding, Engaging, and Supporting at the Bedside

Written by experts in the field, Families in the Intensive Care Unit: A Guide to Understanding, Engaging and Supporting at the Bedside is a state-of-the-art reference for all clinicians who work with families in the ICU.... read more

Baricitinib in COVID-19 Patients

Baricitinib in COVID-19 Patients

In patients hospitalized with COVID-19, baricitinib significantly reduced the risk of death but the size of benefit was somewhat smaller than that suggested by previous trials. The total randomized evidence to date suggests... read more

Developing a Decision Instrument to Guide Abdominal-pelvic Imaging of Blunt Trauma Patients

Developing a Decision Instrument to Guide Abdominal-pelvic Imaging of Blunt Trauma Patients

Although computed tomography (CT) of the abdomen and pelvis (A/P) can provide crucial information for managing blunt trauma patients, liberal and indiscriminant imaging is expensive, can delay critical interventions, and... read more

Expert Consensus on PeRcutaneous Cannulation for ECPR

Expert Consensus on PeRcutaneous Cannulation for ECPR

We present inclusion and exclusion criteria and a comprehensive, detailed, generalizable list of best practices for extracorporeal cardiopulmonary resuscitation (ECPR) initiation following refractory out-of-hospital cardiac... read more

Bleeding and Thrombotic Events in Patients with Severe COVID‑19 on ECMO

Bleeding and Thrombotic Events in Patients with Severe COVID‑19 on ECMO

In a nationwide cohort of COVID‑19 patients supported by extracorporeal membrane oxygenation (ECMO), bleeding incidence was high and associated with mortality. Intracranial hemorrhage incidence was higher than reported... read more

Nasotracheal Intubation on Postoperative Neonates with Congenital Heart Disease

Nasotracheal Intubation on Postoperative Neonates with Congenital Heart Disease

Nasotracheal intubation (NTI) is feasible and safe in neonatal cardiac surgery. System-level engagement with stakeholders is necessary to change clinical practice. NTI facilitates early SLP evaluation and treatment and significantly... read more

Trauma, Eighth Edition

Trauma, Eighth Edition

Hailed by readers and reviewers for its expert authorship and high-yield clinical content, Trauma is unquestionably the field's definitive text. Enhanced by a full-color design and a high-quality atlas of anatomic drawings... read more

Postoperative Sepsis Infection Can Be Identified Using Gene Expression Signatures

Postoperative Sepsis Infection Can Be Identified Using Gene Expression Signatures

Host biomarker signatures may be able to identify postoperative infection or sepsis up to three days in advance of clinical recognition. If validated in future studies, these signatures offer potential diagnostic utility... read more

Evaluation of an Advanced Critical Care Echocardiography Program

Evaluation of an Advanced Critical Care Echocardiography Program

Trainees perceived lack of time and limited access to supervision as major barriers to course completion. Nevertheless, successful portfolio completion was related to factors other than protected time in the echocardiography... read more

CRT-targeted Fluid Resuscitation vs. Lactate-targeted in Septic Shock

CRT-targeted Fluid Resuscitation vs. Lactate-targeted in Septic Shock

Capillary refill time (CRT)-targeted fluid resuscitation in septic shock was not superior to a lactate-targeted one on early fluid administration or fluid balances. However, it was associated with comparable effects on regional... read more

Mental Health Morbidity Among Caregivers

Mental Health Morbidity Among Caregivers

While much of the research on post-ICU mental health morbidity has focused upon the survivors themselves, emerging data shows that caregivers of ICU patients are similarly impacted. The collective sequelae experienced... read more

Public Sepsis Awareness Campaigns Should Be Created Based on Local Data

Public Sepsis Awareness Campaigns Should Be Created Based on Local Data

Although public knowledge of sepsis and its mortality is generally low, some countries have high awareness and knowledge, and as such, any public awareness campaigns should be created based on local data. This will also... read more

Trends in Time to Extubation for Pediatric Postoperative Cardiac Patients

Trends in Time to Extubation for Pediatric Postoperative Cardiac Patients

In this large, multicenter database study, early extubation rates in postoperative cardiac patients did not significantly change between 2009 and 2018. Centers that performed early extubation more frequently did not have... read more

MECA in Medical Emergency Situations Significantly Reduced Failure Rates

MECA in Medical Emergency Situations Significantly Reduced Failure Rates

In our simulation, the use of medical emergency cognitive aid (MECA) in medical emergency situations significantly reduced failure rates. The use of MECA was widely accepted, and MECA were easy to use. In a high percentage,... read more

Optimizing the Design and Analysis of Future AKI Trials

Optimizing the Design and Analysis of Future AKI Trials

Acute kidney injury (AKI) is a complex clinical syndrome associated with an increased risk of morbidity and mortality, particularly in critically ill and perioperative patient populations. Most AKI clinical trials have... read more

Fear and Insight in the ICU Bed

Fear and Insight in the ICU Bed

Mid-morning dressing changes, hours wasted, going through each cut methodically. Dressing off, wound cleaned, redressed. The brunt of pain dealt with by nature before giving in. The intensive care unit (ICU) nurse offers... read more

Feelings of Strangeness in ICU Patients

Feelings of Strangeness in ICU Patients

After several weeks in the intensive care unit (ICU) following a lung infection, Mr Pol wakes up from a coma and gradually becomes aware of his situation. The healthcare team rejoice in the successful outcome of his extubation:... read more