Stories Category: Intensive Care
Obstructive Airway Diseases: Role of Lipid Mediators
Incidences of inflammatory airway diseases are on the rise across the world. Existing therapeutic options are ineffective, unsafe, and expensive, and severe cases are nonresponsive to conventional therapy. Therefore, it is... read more
Association Between Dexamethasone Treatment for COVID-19 Patients and Rates of Hospital Readmission and Mortality
Current guidelines recommend use of dexamethasone, 6 mg/d, up to 10 days or until discharge for patients hospitalized with COVID-19. Whether patients who received less than 10 days of corticosteroids during hospitalization... read more
Chronic Obstructive Pulmonary Disease, An Issue of Clinics in Chest Medicine
This issue of Clinics in Chest Medicine, guest-edited by Dr. Gerard Criner and Dr. Bartolome Celli, is focused on Chronic Obstructive Pulmonary Disease. Topics discussed in this issue include but are not limited to: COPD... read more
Electronic Pneumonia Decision Support Helps Reduce Mortality by 38% in Community Hospitals
Pneumonia was the leading cause of death from infectious diseases in the United States, even before the COVID-19 pandemic, and continues to be a leading cause of death. In the study, researchers at Intermountain Healthcare... read more
Sotrovimab Effect Among High-risk COVID-19 Patients
Among nonhospitalized patients with mild to moderate COVID-19 and at risk of disease progression, a single intravenous dose of sotrovimab, compared with placebo, significantly reduced the risk of a composite end point of... read more
Critically Ill Pregnant Women with COVID-19: Management and Outcome
Coronavirus disease 2019 (COVID-19)-infected pregnant women are at higher risk of intensive care unit (ICU) admission and mechanical ventilation. Because reports describing the clinical course and management of critically... read more
Percussion Pacing – An Almost Forgotten Procedure for Hemodynamically Unstable Bradycardias?
More than 80 years after its first description by Eduard Schott, percussion (fist) pacing remains a little known procedure even though it represents an instantly available and easy to perform treatment for temporary emergency... read more
Handbook of Corticosteroids
Corticosteroids are a class of steroid hormones which are mainly produced in the adrenal cortex of the vertebrates but are also synthesized artificially. They ease redness, itching, swelling and allergic reactions. There... read more
Sepsis Hospitalization and Risk of Subsequent Cardiovascular Events in Adults
Adult sepsis survivors experience an increased hazard of major cardiovascular events compared to survivors of a non-sepsis hospitalization. 254,241 adult sepsis survivors were matched to adult survivors of non-sepsis hospitalization... read more
Effect of Bradykinin Receptor Antagonism on ACE Inhibitor-associated Angioedema
This study compared the effect of placebo versus the bradykinin B2 receptor antagonist icatibant on symptoms of ACE inhibitor–associated angioedema in a mixed race population of patients. The study does not support the... read more
Buprenorphine-Precipitated Opioid Withdrawal in the ED
Buprenorphine-precipitated opioid withdrawal is seen in patients physically dependent on opioids who have recently taken full-agonist opioids and are then administered buprenorphine. Patients with severe withdrawal commonly... read more
Why Are We Still Talking about ICP and Ketamine?
A trauma patient required emergent intubation during a recent shift. The altered patient was suspected of having an intracranial bleed. My resident was concerned about rapid onset of hypoxia and other internal injuries causing... read more
Epidemiology and Outcomes of Critically Ill Children at Risk for PARDS
The Pediatric Acute Lung Injury Consensus Conference “at-risk for pediatric acute respiratory distress syndrome” criteria identify critically ill children at high risk of pediatric acute respiratory distress syndrome... read more
Therapeutic Hyperthermia Associated with Improved Survival in Afebrile Critically Ill Patients with Sepsis
Participants randomized to external forced-air warming did not have a difference in HLA-DR expression or IFN-γ production. In this pilot study, however, 28-day mortality was lower in the intervention group. Future research... read more
Melatonin in ICU Delirium: Shining Light on the Hormone of Darkness
Delirium represents a form of acute brain dysfunction predictive of excess death and long-term cognitive impairment in critically ill patients. For many years, we have wondered whether pharmacological doses of melatonin would... read more
Clinical, Biological and Molecular Aspects of COVID-19
The novel coronavirus 2019 (COVID-19) has caused a serious global pandemic in just eight months. Nearly every country and territory in the world has been affected by the virus. The virulence and infection rate of the... read more
Weaning from Ventilation and Extubation of Children in Critical Care
By reading this article, you should be able to: - Identify the predictors of successful extubation in pediatric ICU (PICU) patients. - Describe the factors affecting mechanical ventilator weaning in PICU patients. -... read more
