Stories Category: Intensive Care
Moderna Vaccine 94.1% Efficacy Preventing Symptomatic COVID-19
The SARS-CoV-2 pandemic continues to be a global health concern. The mRNA-1273 (Moderna) vaccine was reported to have an efficacy of 94.1% at preventing symptomatic COVID-19 due to infection with ‘wild-type’ variants... read more
COVID-19 Surges Increased Patient Mortality
A recent study by scientists at the National Institutes of Health suggests that one in every four COVID-19 deaths in the United States may be attributed to hospitals strained by surging caseloads. Published in the Annals... read more
Reduced Sensitivity of COVID-19 Variant Delta to Antibody Neutralization
The SARS-CoV-2 B.1.617 lineage was identified in October 2020 in India1–5. It has since then become dominant in some indian regions and UK and further spread to many countries6. The lineage includes three main subtypes... read more
Sepsis: Clinical Diagnosis and Treatment
Sometimes our body's reaction to infection can result in damage to internal tissues and organs. Such a condition is referred to as sepsis. Some of the symptoms of sepsis are high fever, increased heart and breathing rate,... read more
New Device for Intubation Through a Laryngeal Mask Airway
On review of the literature, it is abundantly obvious that an endotracheal tube (ETT) with a posterior-facing bevel and curved or tapered tip to center the tube on the scope and reduce hang-up is ideal for intubation over... read more
Oxygen Therapy in COVID-19 Patients: The Role of HFNC and CPAP
Oxygen therapy and non-invasive ventilation in COVID-19 should be based on pathophysiological changes and a step-by-step approach should be adopted in choosing the right therapeutic strategy for each patient. Continuous... read more
Thrombosis vs. Hemorrhage Rates in Patients with Severe Respiratory Failure Due to COVID-19
Significant rates of pulmonary thromboembolism and of catheter-associated deep vein thrombosis were seen in both viral infections but were greater in those requiring the use of extracorporeal membrane oxygenation in coronavirus... read more
Is Daily Enoxaparin Dosing As Good As Twice Daily?
Venous thromboembolism (VTE) remains a big problem for trauma professionals and the patients they take care of. Every trauma center has some sort of VTE prophylaxis protocol for stratifying risk, prescribing mechanical... read more
Clinical Trials Design Evaluating Sedation in Critically Ill Adults Requiring Mechanical Ventilation
These recommendations are intended to assist researchers in the design, conduct, selection of endpoints, and reporting of clinical trials involving sedative medications and/or sedation protocols for adult ICU patients who... read more
Single-use Endoscopy
Endoscopy is used in a variety of medical specialties ranging from gastroenterology to urology, cardiology and critical care. Traditionally, health systems have invested in reusable endoscopy equipment, but an industrywide... read more
Baseline FeNO as a prognostic biomarker for subsequent severe asthma exacerbations
In uncontrolled, moderate-to-severe asthma, higher baseline FeNO levels were associated with greater risk of severe asthma exacerbations, particularly in combination with elevated eosinophil count and prior exacerbations,... read more
Melatonin for Delirium Prevention in Hospitalized Patients
Melatonin/ramelteon are associated with reduction in delirium incidence in hospitalized patients. However, this effect seems confined to surgical and ICU patients. The optimum dosage and formulation of melatonin, and... read more
Preoperative vena cava filter placement in recurrent cerebral fat embolism following traumatic multiple fractures
Despite scarce evidence, we reckon that Inferior Vena Cava Filter (IVCF) could improve prognosis in selected patients with fat embolism syndrome (FES), especially those presenting high risk factors, after accurately weighing... read more
Distinct antibody responses to SARS-CoV-2 in children and adults across the COVID-19 clinical spectrum
Clinical manifestations of COVID-19 caused by the new coronavirus SARS-CoV-2 are associated with age. Adults develop respiratory symptoms, which can progress to acute respiratory distress syndrome (ARDS) in the most severe... read more
REGN monoclonal antibodies work in selected hospitalised COVID-19 patients
New findings suggest a significant benefit from REGN in terms of the primary outcome of mortality for patients who have low levels of their own antibodies at the time of admission. This was an unexpected result for me... read more
Multimorbidity on Long-Term Outcomes Following ICU Discharge
This national cohort study has demonstrated increased resource use for critical care survivors in the year following discharge but fails to replicate past findings of increased longer-term mortality. Multimorbidity, lifestyle... read more
Percutaneous Dilational Tracheostomy for COVID-19 Patients Requiring Mechanical Ventilation
Patients with COVID-19 who survive the early days of MV experience severe and prolonged respiratory failure. An early modified percutaneous dilational tracheostomy (PDT) was safe for patients and healthcare providers and... read more
