Stories Category: Intensive Care
Colchicine, the only effective oral medication for treating non-hospitalized COVID-19 patients
The Montreal Heart Institute announced COLCORONA clinical trial has provided clinically persuasive results of colchicine's efficacy to treat COVID-19. The study results show that colchicine reduces the risk of death or... read more
Prone Positioning Non-intubated COVID-19 Patients with Severe Hypoxemia Was Safe
In a small sample, prone positioning non-intubated COVID-19 patients with severe hypoxemia was safe; however, many patients did not tolerate prolonged durations. Although patients had improved oxygenation and respiratory... read more
Full-dose blood thinners decreased need for life support and improved outcomes in COVID-19 patients
Full dose anticoagulation (blood thinner) treatments given to patients hospitalized for COVID-19 reduced the requirement of vital organ support in a large clinical trial conducted worldwide. With large numbers of COVID-19... read more
RAPID UPDATE: Clinical Guide for the Management of Critical Care for Adults with COVID-19
This RAPID UPDATE to the FICM/ICS "Clinical guide for the management of critical care for adults with COVID-19 during the Coronavirus pandemic" highlights five clinically urgent issues for practising clinicians caring for... read more
Tocilizumorelikeit? The latest data on Tocilizumab
Our hats were then blown away when the REMAP-CAP team and the UK government fired an evidence-based carpet bomb in our direction. We saw a trial press release, a preprint article, an alert letter from the MHRA/DHSC, national... read more
Antimicrobial‑associated Harm in Critical Care
The belief that, for the individual patient, the benefit of prompt and continued use of antimicrobials outweighs any potential harm is a significant barrier to improved stewardship of these vital agents. Antimicrobial... read more
ICU Strain and Mortality Risk Among Critically Ill Patients with COVID-19
The coronavirus disease 2019 (COVID-19) pandemic has affected numerous communities, and reports of overburdened hospitals, specifically critical care units, have become commonplace. High-quality supportive care remains the... read more
De Novo Renal Failure and Clinical Outcomes of Patients With Critical COVID-19
This case series concludes that respiratory failure conveys significant mortality risk in patients with coronavirus disease 2019 and that survival with concomitant renal failure is rare. This is a case series of patients... read more
Harnessing a Pioneering Cell Therapy Treatment for COVID-19 Patients with ARF
A world-leading UK-wide trial supported by NIHR is offering a pioneering cell therapy treatment for patients with acute respiratory failure (ARF) caused by COVID-19. The groundbreaking study, led by experts at Queen's... read more
Overcoming Enteral Nutrition Delivery Challenges in Critical Care
It is the essential implementation of this new evidence occurs to overcome real and perceived EN challenges. This data should lead to increased standardization/protocolization of ICU nutrition therapy to ensure personalized... read more
Adjuvant therapeutic plasma exchange in septic shock
The hallmark of sepsis is a pathological host response to an infection that may lead to organ dysfunction, shock and high mortality. Besides numerous circulating mediators initiating inflammation, vascular barrier breakdown... read more
Is Cardiopulmonary Resuscitation Futile in COVID-19 Patients Experiencing In-Hospital Cardiac Arrest?
COVID-19 patients suffering from in-hospital cardiac arrest had 100% in-hospital mortality regardless of the baseline comorbidities, presenting illness severity, and location of arrest. Out of 1,094 patients hospitalized... read more
Bacterial Superinfection Pneumonia in COVID-19 Respiratory Failure
Severe community-acquired pneumonia secondary to SARS-CoV-2 is a leading cause of death. Current guidelines recommend patients with SARS-CoV-2 pneumonia receive empirical antibiotic therapy for suspected bacterial superinfection,... read more
COVID-19 Pneumonia: Typical or Atypical Form of ARDS?
Evidence-based guidelines can never help a doctor resolve whether a patient is best managed by inserting an endotracheal tube or avoiding its use. That decision is based on clinical judgment, gestalt, and tacit knowledge.... read more
Deep RNA Sequencing of ICU Patients with COVID-19
Current upper respiratory tract testing for COVID-19 only determines if the virus is present. Deep RNA sequencing with appropriate computational biology may provide important prognostic information and point to therapeutic... read more
Pre-hospital critical care management of severe hypoxemia in victims of COVID-19
Patients with Covid-19 and severe hypoxemia may pose a considerable challenge for the pre-hospital emergency medical services. Intubation may be associated with a high risk of complications in these patients and should be... read more
Circuits Between Infected Macrophages and T Cells in COVID-19 Pneumonia
Some patients infected with Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) develop severe pneumonia and the acute respiratory distress syndrome (ARDS). Distinct clinical features in these patients have led... read more
