Tag: analysis
Delayed Intubation Linked to Poor Outcome
The optimal timing of endotracheal intubation in critically ill patients requiring invasive mechanical ventilation remains undefined. A new analysis of the large, prospective Intensive Care Over Nations (ICON) database compares... read more
Effect of a National Standard for Deteriorating Patients on Intensive Care Admissions Due to Cardiac Arrest in Australia
The main objective of this study is to assess whether a national standard for improving care of deteriorating patients affected ICU admissions following cardiac arrests from hospital wards. Introducing a national standard... read more
TAC on Computed Tomography and the Risk of COPD Progression
Total Airway Count (TAC) may reflect the airway-related disease changes that accumulate in the “quiet” zone in early/mild Chronic Obstructive Pulmonary Disease (COPD), indicating that TAC acquired with commercially available... read more
Effect of Individualized vs Standard Blood Pressure Management Strategies on Postoperative Organ Dysfunction
Effect of Individualized vs Standard Blood Pressure Management Strategies on Postoperative Organ Dysfunction Among High-Risk Patients Undergoing Major Surgery. Among patients predominantly undergoing abdominal surgery who... read more
Severity of Illness Scores May Misclassify Critically Ill Obese Patients
Severity of illness scores rest on the assumption that patients have normal physiologic values at baseline and that patients with similar severity of illness scores have the same degree of deviation from their usual state.... read more
The Contents of a Patient Diary and its Significance in the ICU
The aim of this study was to describe the contents of a patient diary and its significance for persons cared for in an ICU. What formerly critically ill patients appreciate most about the diary is that the diary is personally... read more
Early Identification of Acute Respiratory Distress Disorder in the Absence of Positive Pressure Ventilation
Almost all patients with pulmonary bilateral infiltrates and a PaO2/FIO2 less than or equal to 300 mm Hg under standard oxygen fulfilled the acute respiratory distress syndrome criteria under noninvasive ventilation within... read more
A Comparison of the qSOFA and SIRS Criteria for the Diagnosis of Sepsis and Prediction of Mortality
Several studies were published to validate quick-SOFA (qSOFA), namely in comparison with Systemic Inflammatory Response Syndrome (SIRS) criteria. We performed a systematic review and a meta-analysis with the aim of comparing... read more
Effect of Boarding on Mortality in ICUs
Mortality increased with boarding of critically ill patients. Further research is needed to identify safer practices for managing patients during periods of high ICU occupancy. The study population consisted of 8,429 patients... read more
Dexmedetomidine-Associated Hyperthermia
Dexmedetomidine-associated hyperthermia: a retrospective cohort study of intensive care unit admissions between 2009 and 2016. Dexmedetomidine-associated hyperthermia has not been previously studied. Analysis is warranted... read more
Regional Variation of Computed Tomographic Imaging and the Risk of Nephrectomy
In this analysis of 306 hospital referral regions, regional CT risk was significantly correlated with nephrectomy, and scanning an additional 1000 Medicare beneficiaries was associated with 4 additional nephrectomies. Beneficiaries... read more
Predicting the Hemodynamic Response to Prone Positioning
Graphical models of physiology are heuristically appealing as they facilitate qualitative conclusions at the bedside of the critically ill. Historically, the Rahn diagram has portrayed the physiology of the lungs, chest wall... read more
Guidelines for the Content of Statistical Analysis Plans in Clinical Trials
While guidance on statistical principles for clinical trials exists, there is an absence of guidance covering the required content of statistical analysis plans (SAPs) to support transparency and reproducibility. Recommendations... read more
The Effect of ICU Out-of-Hours Admission on Mortality
Adjusted risk of death for ICU admission was greater over the weekends compared with weekdays. The absence of a dedicated intensivist on-site overnight may be associated with increased mortality for acute admissions. These... read more
Improving Handovers By Learning From Ferrari Team
We were able to improve our vulnerable processes by translating good practice found in two industries – aviation and motor racing – into healthcare. We were able to do this by taking into account the subtle complexities... read more
Diagnostic Importance of Pulmonary Interleukin-1β and Interleukin-8 in VAP
BALF IL-1β and IL-8 are amongst the strongest markers yet identified for accurately demarcating VAP within the larger population of patients with suspected VAP. These findings have potential implications for reduction in... read more
The Role of Hospital Pharmacist in the Screening, Prevention and Treatment of Delirium
An interdisciplinary approach is fundamental for effective prevention and treatment of delirium. Pharmacists could play a role in identifying and resolving medication-related delirium. However, little is known about their... read more
