Little Black Book of Pulmonary Medicine

Little Black Book of Pulmonary Medicine

This succinct, bulleted handbook is the ultimate resource for pulmonary and respiratory specialists. Throughout the book, tables and figures summarize important clinical data and current professional society recommendations,... read more

Significant Persistent Pain Symptoms After Critical Care Illness

Significant Persistent Pain Symptoms After Critical Care Illness

Persistent pain could be a common health problem after critical illness care. Our data also suggest that there is a lack of specific follow-up after ICU discharge. Given the major consequences on patient quality of life,... read more

MACE in Acute Exacerbation of COPD – Troponin I – A Dramatic Predictor

MACE in Acute Exacerbation of COPD – Troponin I – A Dramatic Predictor

The burden of COPD is rising due to continued exposure to risk factors that trigger lung inflammation and repeated secondary infections thereby contributing to the third leading cause of death globally. More COPD deaths... read more

Chronic Obstructive Pulmonary Disease, An Issue of Clinics in Chest Medicine

Chronic Obstructive Pulmonary Disease, An Issue of Clinics in Chest Medicine

This issue of Clinics in Chest Medicine, guest-edited by Dr. Gerard Criner and Dr. Bartolome Celli, is focused on Chronic Obstructive Pulmonary Disease. Topics discussed in this issue include but are not limited to: COPD... read more

Sotrovimab Effect Among High-risk COVID-19 Patients

Sotrovimab Effect Among High-risk COVID-19 Patients

Among nonhospitalized patients with mild to moderate COVID-19 and at risk of disease progression, a single intravenous dose of sotrovimab, compared with placebo, significantly reduced the risk of a composite end point of... read more

Patients’ Perspectives on Point-of-Care Diagnostics in Acute COPD Exacerbations

Patients’ Perspectives on Point-of-Care Diagnostics in Acute COPD Exacerbations

Patients' perspectives showed that point-of-care diagnostics and treatment of acute COPD in exacerbation was considered a qualitative offer by the patients and their relatives. At the same time, it was crucial that the emergency... read more

Procalcitonin in the ED: The evidence

Procalcitonin in the ED: The evidence

Is procalcitonin of any value in the emergency department? Considering that procalcitonin testing is not available in any of my hospitals, I have never been all that interested in this question. But Swami requested a procalcitonin... read more

Noninvasive Respiratory Support for COVID-19 Patients: When, for Whom, and How?

Noninvasive Respiratory Support for COVID-19 Patients: When, for Whom, and How?

The significant mortality rate and prolonged ventilator days associated with invasive mechanical ventilation (IMV) in patients with severe COVID-19 have incited a debate surrounding the use of noninvasive respiratory support... read more

Prescription Rates Changes for Inhaled Corticosteroids During the COVID-19 Pandemic

Prescription Rates Changes for Inhaled Corticosteroids During the COVID-19 Pandemic

During the COVID-19 pandemic, despite early concerns the impact oral corticosteroids might have on the effects of acute COVID-19 reported by the WHO and the potential severity of disease in patients with asthma and chronic... read more

Facemask vs. Helmet – Noninvasive Ventilation

Facemask vs. Helmet – Noninvasive Ventilation

We use Noninvasive ventilation (NIV) to treat various disease processes, such as acute hypercapnic and hypoxemic respiratory failure, post-extubation failure, and neuromuscular diseases. Data supports NIV use in some conditions,... read more

Baseline FeNO as a prognostic biomarker for subsequent severe asthma exacerbations

Baseline FeNO as a prognostic biomarker for subsequent severe asthma exacerbations

In uncontrolled, moderate-to-severe asthma, higher baseline FeNO levels were associated with greater risk of severe asthma exacerbations, particularly in combination with elevated eosinophil count and prior exacerbations,... read more

Steer Clear of Magnesium for COPD

Steer Clear of Magnesium for COPD

Knowingly or not, we in emergency medicine tend to lean into the Dutch hypothesis, a 1960s postulate that asthma and COPD are part of a spectrum of common disease (chronic obstructive lung disease), and should be considered... read more

Association Between Pre-Existing Respiratory Disease and COVID-19

Association Between Pre-Existing Respiratory Disease and COVID-19

Previous studies suggested that the prevalence of chronic respiratory disease in patients hospitalised with COVID-19 was lower than its prevalence in the general population. The aim of this study was to assess whether... read more

Expanding Post-Discharge Readmission Metrics in Patients with COPD

Expanding Post-Discharge Readmission Metrics in Patients with COPD

Of 1,384,025 hospitalizations, 11,304 encounters from 8097 patients met criteria to be index hospitalizations. Most index hospitalizations were inpatient hospitalizations (74.8%) versus observation hospitalizations (25.2%).... read more

Temporal Changes in the Epidemiology, Management, and Outcome from ARDS

Temporal Changes in the Epidemiology, Management, and Outcome from ARDS

The frequency of and outcome from ARDS remained relatively stable between 2002 and 2012. Plateau pressure > 29 cmH2O and driving pressure > 14 cmH2O on the first day of mechanical ventilation but not tidal volume > 8... read more

Prediction Model for Severe CAP among Patients with Diabetes Mellitus

Prediction Model for Severe CAP among Patients with Diabetes Mellitus

Diabetes is an independent risk factor for the development of severe community-acquired pneumonia (CAP) and associated with pneumonia-related hospitalization as well as mortality. Here, we assessed several selected biomarkers... read more

The voice of people living with COPD: what I learned from doing qualitative research

The voice of people living with COPD: what I learned from doing qualitative research

As a general respiratory physician, schooled in the clinical world of evidence-based medicine (EBM), I shared a common view that qualitative research was, well, flaky. Where was the science? The statistical significance?... read more