Tag: COPD
Baseline FeNO as a prognostic biomarker for subsequent severe asthma exacerbations
In uncontrolled, moderate-to-severe asthma, higher baseline FeNO levels were associated with greater risk of severe asthma exacerbations, particularly in combination with elevated eosinophil count and prior exacerbations,... read more
Steer Clear of Magnesium for COPD
Knowingly or not, we in emergency medicine tend to lean into the Dutch hypothesis, a 1960s postulate that asthma and COPD are part of a spectrum of common disease (chronic obstructive lung disease), and should be considered... read more
Association Between Pre-Existing Respiratory Disease and COVID-19
Previous studies suggested that the prevalence of chronic respiratory disease in patients hospitalised with COVID-19 was lower than its prevalence in the general population. The aim of this study was to assess whether... read more
Expanding Post-Discharge Readmission Metrics in Patients with COPD
Of 1,384,025 hospitalizations, 11,304 encounters from 8097 patients met criteria to be index hospitalizations. Most index hospitalizations were inpatient hospitalizations (74.8%) versus observation hospitalizations (25.2%).... read more
Temporal Changes in the Epidemiology, Management, and Outcome from ARDS
The frequency of and outcome from ARDS remained relatively stable between 2002 and 2012. Plateau pressure > 29 cmH2O and driving pressure > 14 cmH2O on the first day of mechanical ventilation but not tidal volume > 8... read more
Prediction Model for Severe CAP among Patients with Diabetes Mellitus
Diabetes is an independent risk factor for the development of severe community-acquired pneumonia (CAP) and associated with pneumonia-related hospitalization as well as mortality. Here, we assessed several selected biomarkers... read more
The voice of people living with COPD: what I learned from doing qualitative research
As a general respiratory physician, schooled in the clinical world of evidence-based medicine (EBM), I shared a common view that qualitative research was, well, flaky. Where was the science? The statistical significance?... read more
All Intensivists Are Not Created Equal
I’d like to preface this story by saying that the majority of the intensivists I have worked with have been exceptional, caring, and professional. We had all established a good camaraderie, and we had mutual respect for... read more
Asthma Among Hospitalized Patients with COVID-19 and Related Outcomes
Among hospitalized patients 65 years or younger with severe COVID-19, asthma diagnosis was not associated with worse outcomes, regardless of age, obesity, or other high-risk comorbidities. Future population-based studies... read more
Critical Care / ICU, Fluids, Electrolytes and Nutrition
Filled with detailed work-ups, treatments, pearls, illustrations, differential diagnosis and references. Everything you ever needed to know about critical care and nutrition issues in an easy to read and navigate format created... read more
The Dyspnoea-inactivity Vicious Circle in COPD: Development and External Validation of a Conceptual Model
The vicious circle of dyspnoea-inactivity has been proposed, but never validated empirically, to explain the clinical course of chronic obstructive pulmonary disease (COPD). We aimed to develop and validate externally... read more
Health Coaching to Increase Appropriate Inhaler Use in COPD
Health coaching may provide a scalable model that can improve care for people living with chronic obstructive pulmonary disease (COPD). Baseline adherence and inhaler technique were uniformly poor and did not differ by... read more
Activin Type II Receptor Blockade for Treatment of Muscle Depletion in COPD
Blocking the action of negative muscle regulators through the activin type II receptors with bimagrumab treatment safely increased skeletal muscle mass but did not improve functional capacity in patients with COPD and low... read more
The Association of Clinical Variables and the Development of Specified Chronic Conditions in ICU Survivors
Clinical variables, especially the reason for ICU admission, are associated with the development of chronic conditions after ICU discharge. Therefore, these clinical variables should be considered when organizing follow-up... read more
Cognitive impairment in chronic obstructive pulmonary disease: disease burden, determinants and possible future interventions
Cognitive impairment (CI) is an important but an under-recognized extra-pulmonary feature of chronic obstructive pulmonary disease (COPD). It is related to the burden of disability, worse health outcomes and impaired self-management.... read more
Climate Change, Global Warming, and Intensive Care
In the last five decades, human activities have resulted in the release of increasing quantities of carbon dioxide and other greenhouse gases, thus contributing to global climate change by additional heating of the atmosphere.... read more
Low-flow Assessment of Current ECMO/ECCO2R Rotary Blood Pumps and the Potential Effect on Hemocompatibility
The role of blood pumps in contributing to adverse effects at the lower blood flow rates used during ECCO2R is shown here to be significant. Current rotary blood pumps should be used with caution if operated at blood... read more
Intensivists’ Preferences for Patient Admission to ICU
ICU consultants vary in the importance they give to different factors in deciding who to prioritize for ICU admission. Transparency regarding which factors have been considered in the decision-making process could reduce... read more
Short-term vs. Conventional Glucocorticoid Therapy in Acute Exacerbations of COPD
In patients presenting to the emergency department with acute exacerbations of Chronic Obstructive Pulmonary Disease (COPD), 5-day treatment with systemic glucocorticoids was noninferior to 14-day treatment with regard to... read more
CDC Launches Investigation Into Surge Of Severe Lung Disease Cases Linked To Vaping
The federal Centers for Disease Control and Prevention (CDC) is investigating the sudden emergence of severe lung disease linked to vaping in 14 states. CDC is providing consultation to the departments of health in Wisconsin,... read more
Risk of Sepsis and Mortality Among Patients with COPD Treated With Angiotensin-Converting Enzyme Inhibitors or Angiotensin Receptor Blockers
Angiotensin receptor blockers were associated with lower rates of sepsis and mortality than angiotensin-converting enzyme inhibitors in the patients with chronic obstructive pulmonary disease. The similar findings were also... read more
Randomized Controlled Trial of Health Coaching for Vulnerable Patients with COPD
These results help inform expectations regarding the limitations and benefits of health coaching for patients with Chronic Obstructive Pulmonary Disease (COPD). They may be useful to health policy experts in assessing the... read more
