Prone Positioning of Nonintubated Patients with COVID-19

Prone Positioning of Nonintubated Patients with COVID-19

Despite the significant variability in frequency and duration of prone positioning and respiratory supports applied, prone positioning was associated with improvement in oxygenation variables without any reported serious... read more

Cerebral Venous Sinus Thrombosis With Thrombocytopenia After Johnson & Johnson Vaccination

Cerebral Venous Sinus Thrombosis With Thrombocytopenia After Johnson & Johnson Vaccination

The initial 12 US cases of Cerebral Venous Sinus (CVST) with thrombocytopenia after Ad26.COV2.S (Janssen/Johnson & Johnson) vaccination represent serious events. This case series may inform clinical guidance as Ad26.COV2.S... read more

Association Between Pre-Existing Respiratory Disease and COVID-19

Association Between Pre-Existing Respiratory Disease and COVID-19

Previous studies suggested that the prevalence of chronic respiratory disease in patients hospitalised with COVID-19 was lower than its prevalence in the general population. The aim of this study was to assess whether... read more

Discharged IMV COVID-19 Survivors Not Functionally Independent

Discharged IMV COVID-19 Survivors Not Functionally Independent

The majority of invasive mechanical ventilation (IMV) COVID-19 survivors were not functionally independent at discharge and required significant follow-up medical care. The COVID-19 circumstance has placed constraints on... read more

Cardiac Markers Implication in Risk-stratification and Management for COVID-19 Patients

Cardiac Markers Implication in Risk-stratification and Management for COVID-19 Patients

COVID-19 patients with pre-existing coronary artery disease represented a higher abnormal percentage of cardiac markers, accompanied by high mortality and ICU admission rate. BNP together with hs-TNI, α- HBDH, CK-MB and... read more

Simulated Identification of Silent COVID-19 Infections Among Children

Simulated Identification of Silent COVID-19 Infections Among Children

In this simulation modeling study of a synthetic US population, in the absence of vaccine availability for children, a targeted approach to rapidly identify silent COVID-19 infections in this age group was estimated to significantly... read more

Host Endothelial, Epithelial and Inflammatory Response in ICU COVID-19 Patients

Host Endothelial, Epithelial and Inflammatory Response in ICU COVID-19 Patients

These studies demonstrate that, unlike other well-studied causes of critical illness, endothelial dysfunction may not be characteristic of severe COVID-19 early after ICU admission. Pathways resulting in elaboration of acute... read more

Rapid Design & Implementation of Post-COVID Clinics

Rapid Design & Implementation of Post-COVID Clinics

Survivors of COVID-19 are a vulnerable population, with complex needs owing to lingering symptoms and complications across multiple organ systems. Those who required hospitalization or intensive care are also at risk for... read more

Clinical Trial of Therapeutics for Severely Ill Hospitalized COVID-19 Patients Begins

Clinical Trial of Therapeutics for Severely Ill Hospitalized COVID-19 Patients Begins

A new Phase 3 trial to test the safety and efficacy of therapeutics for COVID-19 has begun enrolling patients hospitalized with life-threatening cases of COVID-19, including those with acute respiratory failure. The trial... read more

A Practical Integrated Radiomics Model Predicting COVID-19 Hospitalization

A Practical Integrated Radiomics Model Predicting COVID-19 Hospitalization

It has been widely demonstrated that radiological imaging significantly contributes to diagnosing and monitoring pulmonary and systemic involvement of patients affected by COVID-19 using different techniques like chest X-ray... read more

Post‑COVID‑19 Syndrome in Outpatients

Post‑COVID‑19 Syndrome in Outpatients

Background Some patients experience long-term symptoms after COVID-19, but data on outpatients with mild-to-moderate COVID-19 are scarce. Objective To describe persisting symptoms more than 3 months after infection in PCR-confirmed... read more

10 Scientific Reasons in Support of Airborne SARS-CoV-2 Transmission

10 Scientific Reasons in Support of Airborne SARS-CoV-2 Transmission

Heneghan and colleagues' systematic review, funded by WHO, published in March, 2021, as a preprint, states: "The lack of recoverable viral culture samples of SARS-CoV-2 prevents firm conclusions to be drawn about airborne... read more

Massive Alveolar Hemorrhage Presenting During the COVID-19 Pandemic

Massive Alveolar Hemorrhage Presenting During the COVID-19 Pandemic

The coronavirus disease (COVID-19) pandemic has challenged healthcare systems and has resulted in complex diagnostic processes for patients with non-COVID-19 pathology. Here, we demonstrate a case of massive alveolar... read more

The Blood-Clot Problem Is Multiplying

The Blood-Clot Problem Is Multiplying

For weeks, Americans looked on as other countries grappled with case reports of rare, sometimes fatal blood abnormalities among those who had received the AstraZeneca vaccine against COVID-19. That vaccine has not yet... read more

Co-infection in Critically Ill Patients with COVID-19

Co-infection in Critically Ill Patients with COVID-19

During previous viral pandemics, reported co-infection rates and implicated pathogens have varied. In the 1918 influenza pandemic, a large proportion of severe illness and death was complicated by bacterial co-infection,... read more

Mortality Outcomes with Hydroxychloroquine and Chloroquine in COVID-19 Patients

Mortality Outcomes with Hydroxychloroquine and Chloroquine in COVID-19 Patients

Substantial COVID-19 research investment has been allocated to randomized clinical trials (RCTs) on hydroxychloroquine/chloroquine, which currently face recruitment challenges or early discontinuation. We aim to estimate... read more

Outcomes of Patients with COVID-19 and Relationship with Lung Ultrasound Signs

Outcomes of Patients with COVID-19 and Relationship with Lung Ultrasound Signs

In patients with COVID-19 pneumonia, Lung Ultrasound Signs (LUS) signs, including the aeration score, were related to respiratory and systemic symptoms 1 month after ultrasound screening examination. In these patients, a... read more