Interim-analysis of the COVID-19 Patients Treated with the Seraph 100 Microbind Affinity Filter Registry

The treatment of COVID-19 patients with Seraph®100 is well tolerated and the circuit failure rate was lower than previously reported for KRT in COVID-19 patients. Mortality corelated with late initiation of Seraph treatment... read more

Interim-analysis of the COVID-19 Patients Treated with the Seraph 100 Microbind Affinity Filter Registry

Obesity, Inflammatory and Thrombotic Markers, and Major Clinical Outcomes in Critically Ill Patients with COVID-19 in the US

In critically ill patients with COVID-19, higher BMI was not associated with death or thrombotic events but was associated with a greater risk of ARDS and AKI-RRT. The lack of an association between BMI and circulating... read more

Obesity, Inflammatory and Thrombotic Markers, and Major Clinical Outcomes in Critically Ill Patients with COVID-19 in the US

Rivaroxaban vs. No Anticoagulation for Post-discharge Thromboprophylaxis After COVID-19 Hospitalisation

In patients at high risk discharged after hospitalisation due to COVID-19, thromboprophylaxis with rivaroxaban 10 mg/day for 35 days improved clinical outcomes compared with no extended thromboprophylaxis. From Oct 8,... read more

Rivaroxaban vs. No Anticoagulation for Post-discharge Thromboprophylaxis After COVID-19 Hospitalisation

Clinical Synopsis of COVID-19: Evolving and Challenging

Coronavirus disease or COVID-19 or SARS-CoV-2 infection is the latest pandemic that has affected humans globally. The disease has manifested itself in several forms and is now the focus of research worldwide. This book... read more

Clinical Synopsis of COVID-19: Evolving and Challenging

A Rare of Case of COVID-19-Related Pericardial Effusion and Cardiac Tamponade

Acute pericarditis involves inflammation of the pericardial sac, which is made of an inner mesothelial visceral layer that surrounds the heart. Normally, this layer produces ~50 mL of fluid to lubricate the heart and... read more

A Rare of Case of COVID-19-Related Pericardial Effusion and Cardiac Tamponade

ARDS and High Blood Endocan Profile During COVID‑19

With great interest, we read the recently published paper by Pascreau et al. concluding that a high blood endocan profile during COVID‑19 distinguishes moderate from severe acute respiratory distress syndrome (ARDS). In... read more

ARDS and High Blood Endocan Profile During COVID‑19

Lopinavir-ritonavir and Hydroxychloroquine for COVID-19 Patients

Recent trials involving steroids and other immunomodulators have shown benefits and contributed to improved care. Given the emerging nature of the virus, several repurposed agents were also considered as potential antiviral... read more

Lopinavir-ritonavir and Hydroxychloroquine for COVID-19 Patients

Identification of Biomarkers, New Treatments, and Vaccines for COVID-19

The novel coronavirus 2019 (COVID-19) has caused a serious global pandemic in just one year. Nearly every country and territory in the world has been affected by the virus. The virulence and infection rate of the virus are... read more

Identification of Biomarkers, New Treatments, and Vaccines for COVID-19

Metabolomic Diferences: COVID-19 vs. H1N1 Influenza in ARDS

This study aimed to compare the specificity of the metabolic alterations induced by COVID-19 or Influenza A pneumonia (IAP) in acute respiratory distress syndrome (ARDS). Our findings support the concept that ARDS is associated... read more

Metabolomic Diferences: COVID-19 vs. H1N1 Influenza in ARDS

COVID-19 Infection Triggers Profibrotic Macrophage Responses and Lung Fibrosis

COVID-19-induced acute respiratory distress syndrome (ARDS) is associated with prolonged respiratory failure and high mortality, but the mechanistic basis of lung injury remains incompletely understood. Here, we analyzed... read more

COVID-19 Infection Triggers Profibrotic Macrophage Responses and Lung Fibrosis

Prevalence of Hepatopancreatic Injury in Patients with COVID-19

COVID-19 can cause liver injury. Mortality, disease severity, and hospital length of stay are increased in COVID-19 patients with hepatopancreatic injury. Forty-five thousand three hundred sixty patients were included... read more

Prevalence of Hepatopancreatic Injury in Patients with COVID-19

MR-proADM Role in the Stratification Risk of COVID-19 Patients Assessed at the Triage of the Emergency Department

During the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, the Emergency Departments have been overrun with suspicious COVID-19 patients, creating a pressing need to optimize resources through risk... read more

MR-proADM Role in the Stratification Risk of COVID-19 Patients Assessed at the Triage of the Emergency Department

COVID-19 and Myocardial Infarction

COVID-19 is a risk factor for myocardial infarction and stroke through self-controlled case series evaluation, a method that has been used to establish the risk of myocardial infarction associated with influenza infection. Regarding... read more

COVID-19 and Myocardial Infarction

Oxygenation Responses Mechanisms to Proning and Recruitment in COVID-19 Pneumonia

In unresolving COVID-19 pneumonia, the respiratory mechanics and the gas-exchange response to prone positioning and recruitment largely depend on the following two factors: perfusion dysregulation and the amount of consolidated... read more

Oxygenation Responses Mechanisms to Proning and Recruitment in COVID-19 Pneumonia

Coronavirus Disease 2019 (COVID-19): Epidemiology, Pathogenesis, Diagnosis, and Therapeutics

This book provides a comprehensive overview of recent novel coronavirus (SARS-CoV-2) infection, their biology and associated challenges for their treatment and prevention of novel Coronavirus Disease 2019 (COVID-19). Discussing... read more

Coronavirus Disease 2019 (COVID-19): Epidemiology, Pathogenesis, Diagnosis, and Therapeutics

WHO Issues Guidelines on the Treatment of Children with MIS Associated with COVID-19

WHO issued updated guidelines on the management of multisystem inflammatory syndrome (MIS) in children associated with COVID-19 (MIS-C). MIS-C is a rare but serious condition where children with COVID-19 develop inflammation... read more

WHO Issues Guidelines on the Treatment of Children with MIS Associated with COVID-19

No Extra Risk For Transferring ECMO COVID-19 Patients

Previous experience has shown that transporting patients on extracorporeal membrane oxygenation (ECMO) is a safe and effective mode of transferring critically ill patients requiring maximum mechanical ventilator support to... read more

No Extra Risk For Transferring ECMO COVID-19 Patients

Post COVID-19 and Patients with and without Pre-existing ILD

A lot remains to be learned about the long-term effects of patients with interstitial lung disease (ILD) who survive COVID-19 infections. Clinicians need to better understand and recognize the effects of post-COVID 19 lung... read more

Post COVID-19 and Patients with and without Pre-existing ILD