Tag: coronavirus
Risk of Death in Hospitalised COVID‐19 Patients Is Not Reduced by Azithromycin Treatment
The effect of antibiotics with potential antiviral and anti‐inflammatory properties are being investigated in clinical trials as treatment for COVID‐19. We are certain that risk of death in hospitalised COVID‐19... read more
ABCDEF Bundle Implementation for ICU Patients During the COVID-19
Regardless of COVID-19 infection status, implementation rates for the ABCDEF bundle, for each element individually and an ICU diary were extremely low for patients without and with COVID-19 infections during the pandemic.... read more
CAPSID Randomized Trial Results for High-dose Convalescent Plasma in COVID-19 Patients
COVID-19 convalescent plasma (CCP) has been considered a treatment option for COVID-19. This trial assessed the efficacy of a neutralizing antibody containing high-dose CCP in hospitalized adults with COVID-19 requiring respiratory... read more
Impact on Mental, Physical and Cognitive functioning of a Critical care sTay during the COVID-19 pandemic
The ongoing pandemic could affect the duration, variety and severity of the mental, physical, and cognitive impairments intensive care unit (ICU) survivors and their families frequently present. We aim to determine the impact... read more
Neurological Complications After First Dose of COVID-19 Vaccines
Emerging reports of rare neurological complications associated with COVID-19 infection and vaccinations are leading to regulatory, clinical and public health concerns. We undertook a self-controlled case series study to investigate... read more
COVID-19 and Critical Illness Neuropathy
We have described COVID patients in the ICU with critical illness neuropathy (CIP). COVID-related CIP could have implications for the functional recovery and rehabilitation strategies. Nerve conduction studies showed a... read more
Interhospital Transfer of COVID-19 Patients Treated with High-flow Nasal Oxygen Therapy
At the start of the COVID-19 pandemic, early intubation was recommended on the basis of worldwide observations of severe hypoxemia. However, some patients were ultimately able to benefit from high-flow nasal cannula (HFNC)... read more
CCSC Encourage Flu Shots Amid COVID-19 Spread
The members of the Critical Care Societies Collaborative (CCSC), which includes the American Association of Critical-Care Nurses (AACN), American College of Chest Physicians (CHEST), American Thoracic Society (ATS), and Society... read more
COVID-19: Restricted Visitation Policies in Acute Care Settings
Patients, families, and healthcare professionals were impacted by restricted visitation polices in acute care settings during COVID-19. The consequences of this approach on patients and families are understudied and warrant... read more
Short-term and Long-term Rates of Postacute Sequelae of COVID-19 Infection
In this systematic review, we evaluated the temporal progression of clinical abnormalities experienced by patients who recovered from an infection with SARS-CoV-2, starting with a mean of 30 days post–acute illness and... read more
COVID-19 Handbook: Navigating the Future of Healthcare
The COVID-19 Handbook: Navigating the Future of Healthcare provides factual, evidence-based information on the coronavirus disease 2019 (COVID-19) pandemic. Presented in a concise PDF format, this valuable COVID-19 resource... read more
Longitudinal Respiratory Subphenotypes in COVID-19 Patients with ARDS
COVID-19-related ARDS has no consistent respiratory subphenotype. Patients diverged from a fairly homogenous to a more heterogeneous population, with trajectories of ventilatory ratio and mechanical power being the most discriminatory.... read more
Suboptimal COVID-19 Vaccination Coverage Implications in Florida and Texas
In July, 2021, another wave of COVID-19 began in the USA as the highly infectious delta (B.1.617.2) SARS-CoV-2 variant drove outbreaks predominantly affecting states with relatively low vaccination coverage. Some US states... read more
ECMO for COVID-19
Mortality after ECMO for patients with COVID-19 worsened during 2020. These findings inform the role of extracorporeal membrane oxygenation (ECMO) in COVID-19 for patients, clinicians, and policy makers. In 2020, 4,812... read more
Dexamethasone 12 mg vs. 6 mg for COVID-19 Patients with Severe Hypoxia
Among patients with COVID-19 and severe hypoxia, dexamethasone 12 mg did not result in statistically significantly more days alive without life support at 28 days than dexamethasone 6 mg. However, the confidence interval... read more
Therapeutic Anticoagulation vs. Usual Care in Noncritically Ill COVID-19 Patients
Among noncritically ill patients with COVID-19 infection, therapeutic anticoagulation with heparin improved the proportion of patients who survived without need for organ support. Therapeutic anticoagulation was associated... read more
We studied how to reduce airborne COVID spread in hospitals. Here’s what we learnt
Melbourne’s second wave of COVID-19 last year, which led to a lockdown lasting more than 100 days, provided us with many lessons about controlling transmission. Some of these are pertinent as New South Wales endures its... read more
COVID-19 and Anticoagulation: Full Dose or Prophylactic Dose?
In CRITICALLY ILL patients with COVID-19, an initial strategy of therapeutic-dose anticoagulation is not associated with a greater probability of survival to hospital discharge or a greater number of days free of cardiovascular... read more
Convalescent Plasma for COVID-19 in Hospitalised Patients
Convalescent plasma (CP) and standard of care (SOC) did not result in a higher proportion of clinical improvement on at day 28 in hospitalised patients with COVID-19 compared to SOC alone. This is an investigator-initiated,... read more
Predicting Adverse Outcomes in COVID-19 Patients Using BV5%
Evidence suggests that vascular inflammation and thrombosis may be important drivers of poor clinical outcomes in patients with COVID-19. We hypothesized that a significant decrease in the percentage of blood vessels with... read more
COVID-19 Immune Evasion by the B.1.427/B.1.429 Variant of Concern
As battles to contain the COVID-19 pandemic continue, attention is focused on emerging variants of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus that have been deemed variants of concern because they... read more
