Predictors of High-flow Nasal Cannula Failure in COVID-19 Patients

A retrospective cohort study was conducted during the months of March and May 2021. Data collection was based on a follow-up of 156 hospitalized patients with a diagnosis of COVID-19 who were users of high-flow nasal cannula... read more

Hematological, Inflammatory and Serological Responses Among COVID-19 ICU Patients

A significant association between serum IgG/IgM and ICU admission was observed. Although serum ferritin and LDH can offer information about the extent of inflammation, they are exclusive factors for ICU admission. Significant... read more

Influenza and COVID-19 Vaccination Rates Among Children Receiving Long-Term Ventilation

Children with tracheostomy and HV are at high risk of morbidity and mortality from viral ARIs. Among MyTRaCh enrollees, we found significant discrepancy between influenza and COVID-19 vaccination status. Compared with... read more

Cardiovascular Complications of COVID-19: Acute and Long-Term Impacts

Cardiovascular Complications of COVID-19: Acute and Long-Term Impacts

This book is the first comprehensive approach on COVID-19 cardiac complications, both during the acute phase as well as in the long-COVID period. It provides an up-to-date and highly illustrated summary of the biology... read more

COVID-19 ARDS Patients vs. Patients with ARDS

Ventilation management may differ between COVID–19 ARDS (COVID–ARDS) patients and patients with pre–COVID ARDS (CLASSIC–ARDS); it is uncertain whether associations of ventilation management with outcomes for CLASSIC–ARDS... read more

Early Reapplication of Prone Position During VV-ECMO for ARDS

A combination of prone positioning (PP) and venovenous extracorporeal membrane oxygenation (VV-ECMO) is safe, feasible, and associated with potentially improved survival for severe acute respiratory distress syndrome (ARDS).... read more

Outcomes of Different Steroid Dosing Regimens in Critical Covid-19 Pneumonia

The study found that high-dose steroids in the treatment of critically ill patients with COVID-19 pneumonia did not confer any mortality benefit and were associated with an increased risk of dysglycemia and superimposed infections. A... read more

Glucose Metabolism Disorders: Pre-hospital Oxygen Therapy and Saturation Variability in COVID-19 Patients

The COVID-19 pandemic has revealed that viruses can have multiple receptor properties, penetrating various tissues and causing mutations in various genes, thus promoting a range of metabolic disorders. The purpose of... read more

Ventilator-associated Pneumonia Risk Factors in Patients with Severe COVID-19

Patients with COVID-19 are at high risk of VAP, which may be related to issues other than prolonged mechanical ventilation (MV) time. Multiple factors increase the chances of these patients developing VAP, including:... read more

Prevalence and Risk Factors of ICU-acquired Weakness in COVID-19 Patients

The prevalence of ICUAW in patients with COVID-19 was considered relatively high. Older age, pre-existing hypertension, medical intervention of prone position, NMBA use, needed tracheostomy and RRT were likely risk factors.... read more

Hospitalizations for Multisystem Inflammatory Syndrome in Children (MIS-C) in US

Multisystem inflammatory syndrome in children (MIS-C) is a rare, serious condition characterized by fever and multiorgan involvement that occurs after SARS-CoV-2 infection. US Centers for Disease Control and Prevention... read more

Lower or Higher Oxygenation Targets in the ICU

This study reported no overall differences comparing a PaO2 target of 8–12 kPa on mortality or days alive without life support in 90 days. Subgroup analyses suggested heterogeneity of treatment effects (HTE) in patients... read more

Antifungal Prophylaxis of COVID-19 Associated Pulmonary Aspergillosis in Ventilated Patients

This study investigated the impact of POSA prophylaxis on risk of CAPA development in mechanically ventilated COVID-19 patients receiving corticosteroids. We observed a significant variation in CAPA incidence rates among... read more

Secretomic Approach Value in COVID-19 Viral Pneumonia Among Patients With Respiratory Distress

this article presents an innovative and promising secretomic analysis to distinguish VPP patients from NV-ICU patients using combinations of protein markers. Among the identified proteins, ficolin-3 and proteoglycan-4 appear... read more

Prevalence and Survival of Prolonged VV ECMO for ARDS

The understanding of prolonged venovenous extracorporeal membrane oxygenation (VV ECMO) in the setting of acute respiratory distress syndrome (ARDS) is evolving and durations of support once considered extreme are now commonplace.... read more

The Existence of Adrenal Insufficiency in COVID-19 Patients with Pneumonia

Patients with a history of COVID-19 pneumonia who present with clinical symptoms such as shock, nausea, vomiting, and fatigue should have hypocortisolism included in the differential diagnosis. These patients should also... read more

COVID-19 Infections Are Growing

Large areas of the US are experiencing a significant spread of COVID-19, with the pandemic reaching alarming levels. Data from the Centers for Disease Control and Prevention indicates that the spread of the disease has officially... read more