Tag: COVID-19
Management of Refractory COPD
Chronic obstructive pulmonary disease (COPD) is a common condition with an estimated global prevalence of almost 12 percent in adults over age 30 years [1-3]. Prior to the onset of the COVID-19 (coronavirus disease 2019)... read more
Invasive Fungal Infections in Non-neutropenic Patients
Critically ill patients, particularly those with features of immunosuppression, are susceptible to invasive fungal infections (IFI), which pose significant diagnostic and therapeutic challenges. Candida and Aspergillus,... read more
Microbial Dynamics and Pulmonary Immune Responses in COVID-19 Secondary Bacterial Pneumonia
Secondary bacterial pneumonia (2°BP) is associated with significant morbidity following respiratory viral infection, yet remains incompletely understood. In a prospective cohort of 112 critically ill adults intubated... read more
Outcomes and inflammation changes in different types of immunocompromised patients with critically ill COVID-19 admitted to ICU
Critically ill COVID-19 patients admitted to the ICU exhibit distinct clinical outcomes based on their immunosuppression status, with cancer patients facing the highest mortality rate due to variations in inflammatory responses... read more
Pulmonary Barotrauma in COVID-19 Patients: Experience From a Tertiary University Hospital
Mechanical ventilation (MV) in COVID-19 patients is often complicated with pulmonary barotrauma. The aim of this study was to determine the incidence and risk factors associated with the development of pulmonary barotrauma... read more
COVID-19 Leaves Lasting Impact on Nursing Practices and Job Satisfaction
The COVID-19 pandemic exacerbated the difficulties nurses experience, especially in emergency departments, requiring adjustments in practice care settings and continuing to impact their overall job satisfaction. Nursing... read more
COVID-19 and the Cardiovascular System: From Pathophysiology to Clinical Management
COVID-19 and the Cardiovascular System: From Pathophysiology to Clinical Management comprehensively covers COVID-19's impact on the cardiovascular system. Coverage includes the pathophysiology, clinical manifestations, diagnostic... read more
Ethics in Intensive Care Medicine (Lessons from the ICU)
In this book, part of the European Society of Intensive Care Medicine (ESICM) textbook series, experts in the field of clinical ethics describe basic principles of clinical ethics and ethical reasoning, the fundamental pillars... read more
Thrombocytopenia and COVID-19 pairing in the ICU: Prognostic influence of thrombocytopenia in resuscitated CoViD-19 patients
CoViD-19 is a viral zoonosis caused by the coronavirus strain (SARS-CoV-2), with acute respiratory failure being its most severe manifestation. Our aim was to determine the influence of thrombocytopenia on the severity and... read more
Blood Eosinophils Matter in Post-COVID-19 Pneumonia
Preliminary results showed that a eosinophil increase during hospitalization could be a potential predictor of pulmonary sequelae in surviving patients after COVID-19 pneumonia. Despite the protective role of eosinophils,... read more
Ineffectiveness of Therapeutic Plasma Exchange – Last Resort in Severe COVID-19
Patients severely infected with SARS-CoV-2 showed fluctuations in inflammatory parameters despite TPE treatment; CRS was not suppressed by TPE; and this treatment did not confer survival benefit in this patient group. A... read more
COVID-19 Pneumonia: Different Respiratory Treatments for Different Phenotypes?
Type L and Type H patients are best identified by CT scan and are affected by different pathophysiological mechanisms. If not available, signs which are implicit in Type L and Type H definition could be used as surrogates:... read more
Oxygen Therapy and Noninvasive Respiratory Supports in Acute Hypoxemic Respiratory Failure
Whereas oxygen supplementation should be initiated for patients with acute hypoxemic respiratory failure defined as PaO2 below 60 mm Hg or SpO2 ... read more
Disease Progression Associated Cytokines in COVID-19 Patients with Deteriorating and Recovering Health Conditions
Understanding the immune response to COVID-19 is challenging due to its high variability among individuals. To identify differentially expressed cytokines between the deteriorating and recovering phases, we analyzed the Electronic... read more
The Impact of COVID-19 Pandemic on Respiratory Syncytial Virus Infection in Children
We observed a lower incidence of RSV infection and a lower rate of hospitalization for RSV during the COVID-19 pandemic. The second RSV season during the COVID-19 pandemic began earlier, lasted longer, and had a lower frequency.... read more
Prediction Model for Safe Early Discharge of Patients with an Infection
By combining readily available parameters, we developed and internally validated a prediction model for safe, early discharge among patients. Further research, preferably in a multi-center setting, is warranted to externally... read more
Predictive Value of Diaphragm and Lung Ultrasonography for Weaning Failure in Critically Ill Patients with ARF Due to COVID-19 Pneumonia
Patients undergoing mechanical ventilation due to respiratory failure require a comprehensive approach to determine the optimal timing for weaning from ventilatory support. Evaluating respiratory mechanics, maximal muscle... read more
Plasma Bioactive Adrenomedullin Predicts Mortality and Need for Dialysis in Critical COVID-19
In this study, serial bio-ADM samples in the ICU had limited predictive power for mortality in critically ill COVID-19 patients when looking at absolute values. Still, relative changes over time showed a much better prediction.... read more
Aspirin Reduces the Need for Mechanical Ventilation by Nearly Half For COVID-19 Patients
Patients hospitalized with COVID-19 and taking aspirin were nearly half as likely to require mechanical ventilation as those with COVID-19 not taking the drug, according to a study of adult patients. The patients were... read more
Sex Differences in the Outcome of Critically Ill COVID-19 Patients
Among patients admitted to ICU for severe COVID-19, males experienced higher severity of illness and more frequent intervention than females. Ultimately, the hazard of death was moderately elevated in males compared to females... read more
Functional Dependence Following ICU-treated Sepsis
Sepsis survivorship was associated with a broad range of new impairments and led to functional dependence in around one quarter of patients. Targeted measures are needed to mitigate the burden of this Post-Sepsis-Syndrome... read more
Veno-Arterial-Venous ECMO in a Patient Undergoing Dialysis and Having Cardiopulmonary Failure Due to COVID-19
COVID-19 can cause cardiomyopathy, a rare cardiovascular disorder that can lead to cardiogenic shock. The cardiac and respiratory symptoms may not occur simultaneously, and it is possible to switch to veno-arterial-venous... read more
