Sotrovimab Effect Among High-risk COVID-19 Patients

Sotrovimab Effect Among High-risk COVID-19 Patients

Among nonhospitalized patients with mild to moderate COVID-19 and at risk of disease progression, a single intravenous dose of sotrovimab, compared with placebo, significantly reduced the risk of a composite end point of... read more

Critically Ill Pregnant Women with COVID-19: Management and Outcome

Critically Ill Pregnant Women with COVID-19: Management and Outcome

Coronavirus disease 2019 (COVID-19)-infected pregnant women are at higher risk of intensive care unit (ICU) admission and mechanical ventilation. Because reports describing the clinical course and management of critically... read more

Clinical, Biological and Molecular Aspects of COVID-19

Clinical, Biological and Molecular Aspects of COVID-19

The novel coronavirus 2019 (COVID-19) has caused a serious global pandemic in just eight months. Nearly every country and territory in the world has been affected by the virus. The virulence and infection rate of the... read more

Indicators for Monitoring COVID-19 Community Levels and Making Public Health Recommendations

Indicators for Monitoring COVID-19 Community Levels and Making Public Health Recommendations

Widespread uptake of COVID-19 vaccines that are highly effective against severe illness and death, the accrual of high rates of vaccine- and infection-induced immunity at the population level, and the availability of effective... read more

Balanced Crystalloids Probably Reduce Mortality in the Critically-Ill

Balanced Crystalloids Probably Reduce Mortality in the Critically-Ill

As remarked by the authors of the recent PLUS trial, a systematic review and meta-analysis of randomized controlled trials comparing balanced resuscitation fluid to 0.9% saline was reported in the New England Journal of Medicine... read more

Palliative Care Consultation and End-of-life Outcomes in Hospitalized COVID-19 Patients

Palliative Care Consultation and End-of-life Outcomes in Hospitalized COVID-19 Patients

Palliative care consultation was not associated with CPR performed at the end-of-life but was associated with increased incidence of comfort care being utilized. These results suggest that utilizing palliative care consultation... read more

Anticoagulation in COVID-19 Patients

Anticoagulation in COVID-19 Patients

Clinical, laboratory, and autopsy findings support an association between COVID-19 and thromboembolic disease. Acute COVID-19 infection is characterized by mononuclear cell reactivity and pan-endothelialitis, contributing... read more

Pediatric Pneumonia Research Priorities in the Context of COVID-19

Pediatric Pneumonia Research Priorities in the Context of COVID-19

Operational research on health system capacities, and evaluating optimized delivery of existing treatments, diagnostics and case management approaches are needed. This list should act as a catalyst for collaborative research,... read more

90% of ECMO-eligible COVID-19 Patients Died Amid Rationing

90% of ECMO-eligible COVID-19 Patients Died Amid Rationing

Nearly 90% of adult COVID-19 patients who were eligible for—but didn't receive—extracorporeal membrane oxygenation (ECMO) during the height of the pandemic died in the hospital owing to a lack of resources, even though... read more

3D Printing PPE During COVID-19 Pandemic

3D Printing PPE During COVID-19 Pandemic

Supply chain disruption during the COVID-19 pandemic has forced healthcare systems to look for alternative ways to meet dramatically increased demand for personal protective equipment (PPE). One potential solution to this... read more

POCUS and Digital Tomosynthesis Correlation When Used with COVID-19 Pneumonia Patients

POCUS and Digital Tomosynthesis Correlation When Used with COVID-19 Pneumonia Patients

Point-of-care ultrasound (POCUS) in primary care has good sensitivity and specificity when compared to digital tomosynthesis as regards the diagnosis of COVID-19 pneumonia in patients with the clinical suspicion of pulmonary... read more

Clinical Profile and Recovery Pattern of Dysphagia in COVID-19 Patients

Clinical Profile and Recovery Pattern of Dysphagia in COVID-19 Patients

COVID-19 considerably impacted swallowing function in the current study. Although many patients recovered within an acceptable timeframe, some experienced persistent severe dysphagia and a protracted recovery with dependence... read more

Cardiovascular Complications of COVID-19: Risk, Pathogenesis and Outcomes

Cardiovascular Complications of COVID-19: Risk, Pathogenesis and Outcomes

This book discusses the evidence behind the relationship between COVID-19 and heart disease based on emerging state-of-the-art data. The rapid and unexpected global spread of the COVID-19 has revealed proportional levels... read more

Ascending Aortic Thrombus After COVID-19 Infection

Ascending Aortic Thrombus After COVID-19 Infection

SARS-CoV-2 predisposes patients to both venous and arterial thromboembolism, including ascending aortic thrombus. The current guidelines for anticoagulation recommend three to six months of continuous anticoagulation... read more