Tag: CRRT
Integration Equals Separation for CRRT Filter Lifespan in ECMO Patients (E-CRRT Trial)
The multicenter randomized controlled E-CRRT Trial, conducted from May 2021 to March 2025 at King Chulalongkorn Memorial Hospital (KCMH) and Central Chest Institute of Thailand (CCIT), compared two strategies for combining... read more
The Falling Count: Platelet Trajectory Post-CRRT Predicts Mortality in AKI
This retrospective cohort study examined the dynamic changes in platelet counts—the platelet trajectory—around the initiation of Continuous Renal Replacement Therapy (CRRT) in over 2,200 critically ill adults with Acute... read more
VA-ECMO in Septic Shock: A High-Stakes, High-Uncertainty Rescue
The use of Veno-Arterial Extracorporeal Membrane Oxygenation (VA-ECMO) as a rescue therapy for refractory septic shock remains a challenging, context-dependent, and uncertain strategy in adults. Current evidence shows... read more
Sepsis Danger: High Ferritin Levels Flag Risk of Acute Liver Injury
This study used data from the MIMIC-IV database (training group) and an external hospital dataset (clinical validation group) to develop and validate a prediction model for sepsis-associated acute liver injury (SALI). The... read more
Sepsis, Hemoglobin, and Harm: Transfusions Hurt When Hemoglobin Hits 10g/dL
Red Blood Cell (RBC) transfusions are common in septic patients, but this study highlights the potential for harm at higher hemoglobin (Hgb) levels. Although they may be physiologically guided up to an Hgb of 9-10g/dL, the... read more
Hemolysis in Septic Patients with Acute Respiratory Failure: Prognostic Implications
This study highlights the critical role of hemolysis in sepsis and acute respiratory failure, showing a strong association with organ dysfunction. Hemolysis is notably frequent, especially in patients with septic shock... read more
Hemodynamic Stabilization Using CRRT and cIVNa Combination Therapy
Compared with conventional continuous renal replacement therapy (CRRT), combination therapy of CRRT and continuous intravenous sodium infusion therapy (cIVNa) increased blood pressure, enhanced urinary volume, and reduced... read more
Management of ARDS COVID-19 Patients Using Hemoperfusion and CRRT
Combined hemoperfusion (HP) and continuous renal replacement therapy (CRRT) hold promise as a potential intervention for severe COVID-19 cases with multiple organ dysfunction, leading to improved clinical outcomes. Fifty-six... read more
Fluid Management Impact on Outcomes in Sequential Extracorporeal Support
Sepsis is a life-threatening condition characterized by dysregulated inflammatory responses, often leading to multiple organ dysfunction and high mortality rates. Continuous renal replacement therapy (CRRT) and extracorporeal... read more
TyG Index And Short-term Mortality in Patients with Cardiogenic Shock
The triglyceride-glucose (TyG) index is significantly associated with short-term mortality in patients with cardiogenic shock (CS) and may serve as a useful biomarker for risk stratification. This retrospective cohort... read more
Clinical Efficacy of Nafamostat Mesylate-assisted CRRT Therapy in SA-AKI Patients
Nafamostat Mesylate (NM)-assisted continuous renal replacement therapy (CRRT) therapy significantly improves the therapeutic efficacy of patients with sepsis-associated acute kidney injury (SA-AKI). This combined approach... read more
Cumulative Fluid Balance During the First Three ICU Days in Septic Patients with Heart Failure
In septic patients with HFpEF, positive fluid balance of CFB-day1 might improve the prognosis of patients. However, from the second day, fluid overload was associated with poor prognosis. Therefore, we propose that on... read more
Favorable Outcomes When Using Prolonged CPR Combined with ECPR
Extracorporeal CPR (ECPR) combined with continuous renal replacement therapy (CRRT) successfully rescues a patient who experienced sudden cardiac arrest for 152 minutes. ECPR is an effective and advanced form of extracorporeal... read more
Managing Recurrent Septic Shock – Dual Blood Purification with CytoSorb and oXiris
This case report presents a patient with recurrent septic shock who experienced significant clinical improvement after receiving adjunctive treatment with a combination of continuous renal replacement therapy (CRRT) using... read more
Developing a Rapid Screening Tool for High-risk ICU Sepsis Patients
This study demonstrates that machine learning-based prediction models for sepsis can enhance clinical outcomes through accurate risk assessment during the critical first 24h of ICU admission. Despite healthcare system... read more
New Insights on CRRT for ARDS
In recent times, the applications of continuous renal replacement therapy (CRRT) beyond kidney‐related conditions have been progressively increasing, and its implementation in randomized controlled trials (RCTs) specifically... read more
Protocolized Fluid Balance Neutralization During CRRT
Bitker et al. report the GO NEUTRAL randomized clinical trial results, which investigated fluid balance neutralization guided by functional hemodynamic monitoring (FHM) protocol versus a standard of care in critically ill... read more
UFNET Fluid Removal Strategy Secured by Hemodynamic Monitoring vs. Standard of Care in patients with CRRT
An early and active UFNET strategy secured by an advanced hemodynamic protocol using dynamic indices of preload dependence had the capacity to control H72 FB in an ICU population of patients with acute circulatory failure,... read more
Advances in Critical Care Pediatric Nephrology: Point of Care Ultrasound and Diagnostics
The book covers advances in critical care pediatric nephrology, including care of sick children with acute kidney injury. The book contains detailed guidance on point of care ultrasound in children with acute kidney injury... read more
Endothelial Activation and Microcirculatory Disorders in Sepsis and Critical Illness
The endothelium is one of the largest organs in the human body and lines the blood vessels and microcirculation of all the vital organs. As such, it functions as a massive and critical surveillance system to orchestrate recognition... read more
Citrate Anticoagulation for CRRT
Regional citrate anticoagulation (RCA) is a viable option for liver failure patients. The pro-posed inducible metabolic pathway hypothesis challenges the belief in hepatic dominance over citrate metabolism during RCA-CRRT.... read more
A nomogram predicting pneumonia after cardiac surgery
Three preoperative indicators (age, preoperative malnutrition, diabetes mellitus), one intraoperative indicator (CPB > 135 min) and three postoperative indicators (moderate to severe ARDS, use of ECMO or IABP or CRRT, MV>... read more
