CRRT for Sepsis-induced Acute Kidney Injury

CRRT for Sepsis-induced Acute Kidney Injury

Sepsis-induced acute kidney injury (SI-AKI) represents the first cause of AKI in ICUs, and renal replacement therapy (RRT) is frequently applied in advanced AKI stages. The debate between 'rescue' indications for RRT start... read more

A modified Delphi process to identify, rank and prioritize quality indicators for CRRT care in critically ill patients

A modified Delphi process to identify, rank and prioritize quality indicators for CRRT care in critically ill patients

We developed a prioritized list of 13 QIs for continuous renal replacement therapy (CRRT) care. Future work should focus on developing validated benchmarks for these QIs and implementing them into CRRT programs. We conducted... read more

Choice of Catheter Size for Infants in Continuous Renal Replacement Therapy

Choice of Catheter Size for Infants in Continuous Renal Replacement Therapy

Small size central vascular catheters display optimal rheologic performances in terms of pressures and flows particularly when the renal replacement therapy (RRT) device is equipped with pumps proportional to central vascular... read more

Complications of Regional Citrate Anticoagulation: Accumulation or Overload?

Complications of Regional Citrate Anticoagulation: Accumulation or Overload?

Based on recent recommendations, the use of Regional Citrate Anticoagulation (RCA) is likely to increase dramatically throughout the world. RCA protocols should aim to minimize the amount of net citrate load delivered to... read more

Dosing Adjuvant Vitamin C in Critically Ill Patients Undergoing CRRT

Dosing Adjuvant Vitamin C in Critically Ill Patients Undergoing CRRT

We read with great interest the recent letter to Critical Care by Marik and Hooper. Vitamin C is increasingly recognized as a crucial compound to alleviate morbidity in critically ill patients. Vitamin C concentrations, however,... read more

Tigecycline in Critically Ill Patients on Continuous RRT

Tigecycline in Critically Ill Patients on Continuous RRT

Despite high dialysability, dialysis clearance displayed only a minor contribution to tigecycline elimination, being in the range of renal elimination in patients without AKI. No dose adjustment of tigecycline seems necessary... read more

Being New in the ICU

Being New in the ICU

Being new in the ICU is not easy. You need to have the passion for critical care so much that you really don’t care how difficult it is. That passion is what gets you through the newbie stress. I was a new grad in the ICU,... read more

Baxter initiates late-stage study of novel therapy for acute kidney injury

Baxter initiates late-stage study of novel therapy for acute kidney injury

Baxter International commences a Phase 3 clinical trial assessing an investigational drug, Prismocitrate 18, that combines a citrate anticoagulant and renal replacement solution.... read more