The Family in Preventing Delirium in the ICU

The Family in Preventing Delirium in the ICU

Extended visits, development of family-mediated activities, and redirection are non-pharmacological strategies that reduce the incidence of delirium in the ICU and offer multiple benefits to the patient and family/caregiver. The... read more

Melatonin in ICU Delirium: Shining Light on the Hormone of Darkness

Melatonin in ICU Delirium: Shining Light on the Hormone of Darkness

Delirium represents a form of acute brain dysfunction predictive of excess death and long-term cognitive impairment in critically ill patients. For many years, we have wondered whether pharmacological doses of melatonin would... read more

Incidence of Delirium in ICU Inpatients After Cognitive Exercise Intervention

Incidence of Delirium in ICU Inpatients After Cognitive Exercise Intervention

In this study, the relevant RCTs on cognitive exercise in ICU inpatients with delirium were screened for systematic evaluation and meta-analysis, aiming to explore the impact of cognitive exercises and routine nursing on... read more

Processed Electroencephalography-guided General Anaesthesia to Reduce Postoperative Delirium

Processed Electroencephalography-guided General Anaesthesia to Reduce Postoperative Delirium

Our primary analysis demonstrated a highly sensitive result with a pooled analysis of trials in which the intervention group adhered to manufacturer's recommended guidelines showing reduced incidence of postoperative delirium... read more

Prophylactic Melatonin for Delirium in Intensive Care (Pro-MEDIC)

Prophylactic Melatonin for Delirium in Intensive Care (Pro-MEDIC)

Enteral melatonin initiated within 48 h of ICU admission did not reduce the prevalence of delirium compared to placebo. These findings do not support the routine early use of melatonin in the critically ill. A total of... read more

Physiological Assessment of Delirium Severity: The Electroencephalographic Confusion Assessment Method Severity Score

Physiological Assessment of Delirium Severity: The Electroencephalographic Confusion Assessment Method Severity Score

The Electroencephalographic Confusion Assessment Method Severity Score (E-CAM-S) is an automated, physiologic measure of delirium severity that predicts clinical outcomes with a level of performance comparable to conventional... read more

Association Between Incident Delirium Treatment with Haloperidol and Mortality in Critically Ill Adults

Association Between Incident Delirium Treatment with Haloperidol and Mortality in Critically Ill Adults

Treatment of incident delirium and its symptoms with haloperidol may be associated with a dose-dependent improvement in survival. Future randomized trials need to confirm these results. Patients were evaluated tid for... read more

Post-acute Neurological Consequences of COVID-19

Post-acute Neurological Consequences of COVID-19

COVID-19 and its neurological consequences particularly burden marginalized communities, and so can only be effectively treated by advancing health equity. Our world has witnessed over 275 million confirmed cases of COVID-19... read more

Preoperative POCUS to Identify Frailty and Predict Postoperative Outcomes

Preoperative POCUS to Identify Frailty and Predict Postoperative Outcomes

Similar to computed tomography measurements of psoas muscle area, preoperative ultrasound measurements of quadriceps depth shows promise in discriminating between frail and not-frail patients before surgery. It was also associated... read more

Dynamic Delirium Severity Trajectories and Healthcare Utilization

Dynamic Delirium Severity Trajectories and Healthcare Utilization

This secondary analysis did not identify a significant relationship between delirium severity trajectories and healthcare utilization or mortality within 2 years of hospital discharge. The overall sample (n = 431) had... read more

Point of Care Venous Doppler Ultrasound

Point of Care Venous Doppler Ultrasound

Accurate assessment of the hemodynamic status is vital for appropriate management of patients with critical illness. As such, there has been a constant quest for reliable and non-invasive bedside tools to assess and monitor... read more

The Nexus Between Sleep Disturbance and Delirium Among Intensive Care Patients

The Nexus Between Sleep Disturbance and Delirium Among Intensive Care Patients

Sleep in intensive care is hampered due to many factors; the clinical environment itself exacerbates sleep disturbance. Research suggests that interventions aimed at improving sleep quality have produced positive effects... read more

Perioperative Dexmedetomidine on the Incidence of Postoperative Delirium

Perioperative Dexmedetomidine on the Incidence of Postoperative Delirium

Delirium occurs commonly following major non-cardiac and cardiac surgery and is associated with: postoperative mortality; postoperative neurocognitive dysfunction; increased length of hospital stay; and major postoperative... read more

Impact of ABCDE Bundle Implementation in the ICU on Specific Patient Costs

Impact of ABCDE Bundle Implementation in the ICU on Specific Patient Costs

Full ABCDE bundle implementation resulted in a decrease in total hospital laboratory costs and total hospital laboratory and diagnostic resource utilization while leading to an increase in physical therapy costs. The full... read more