Diagnostic Accuracy of Point-of-Care Ultrasound for Shock

In this study, the identification of the etiology of shock by Point-of-Care Ultrasound (POCUS) was characterized by high sensitivity and a positive likelihood ratio, especially for obstructive shock. Hence, these findings... read more

Diagnostic Accuracy of Point-of-Care Ultrasound for Shock

Resuscitative TEE

The use of ED resuscitative transesophageal echocardiography (TEE) is a practical modality that provides useful diagnostic and therapeutic information for critically ill patients in the emergency department, with an excellent... read more

Resuscitative TEE

Heparin-induced Thrombocytopenia in the Intensive Care Setting

Heparin-induced thrombocytopenia (HIT) is a serious iatrogenic complication of heparin treatments. The diagnosis of HIT is difficult in the intensive care setting because thrombocytopenia is a frequent and multifactorial... read more

Heparin-induced Thrombocytopenia in the Intensive Care Setting

Differential Diagnosis and Cause-specific Treatment During OHCA

The cardiopulmonary resuscitation (CPR) guidelines recommend identifying and correcting the underlying reversible causes of out-of-hospital cardiac arrest (OHCA). However, it is uncertain how often these causes can be... read more

Differential Diagnosis and Cause-specific Treatment During OHCA

Clinical Cases in Critical Care

In Clinical Cases in Critical Care, the authors explore core clinical topics and basic sciences in a practical and realistic way, and include comprehensive discussions focusing on critically unwell patients with a variety... read more

Clinical Cases in Critical Care

ICU Precision Diagnosis with Metagenomic Sequencing

Despite promising results, metagenomics remains underutilized in the ICU. Several factors still limit its inclusion in routine critical care, including the lack of definitive clinical trials testing its utility, few laboratories... read more

ICU Precision Diagnosis with Metagenomic Sequencing

Advances in Microbiology, Infectious Diseases and Public Health: Volume 15

This book series focuses on current progress in the broad field of medical microbiology, and covers both basic and applied topics related to the study of microbes, their interactions with human and animals, and emerging issues... read more

Advances in Microbiology, Infectious Diseases and Public Health: Volume 15

Sick Children Identification in Acute Care Settings

At the heart of every pediatric consultation is the clinician’s responsibility to determine ‘is this child sick?’ In pediatrics illustrative language communicates a clinical picture of the child before us. When... read more

Sick Children Identification in Acute Care Settings

Early Identification of Intra-abdominal Infection and Sepsis

This case report illustrates the ability of the novel biomarker pancreatic stone protein (PSP) concentrations to act as a warning sign, allowing the early identification of intra-abdominal infection and post-operative peritonitis... read more

Early Identification of Intra-abdominal Infection and Sepsis

Delphi Approach to 5-level Priority Triage Systems

This study proposes a standard of 49 outcomes divided into two sets tied to red and orange priority respectively, to be used when evaluating 5-level priority triage systems; Lund Outcome Set for Evaluation of Triage (LOSET).... read more

Delphi Approach to 5-level Priority Triage Systems

Early evaluation of heart rate variability can predict the outcome of patients in the ICU

The study evaluated the use of heart rate variability (HRV) to predict the outcome of patients in the ICU. HRV is a way to evaluate the cardiac effects of the autonomic nervous system, and a relation between HRV and outcome... read more

Early evaluation of heart rate variability can predict the outcome of patients in the ICU

Heterogeneity in Pediatric ARDS: Challenges and Complexities in Diagnosis and Treatment

Pediatric intensive care physicians are well-acquainted with the concept of heterogeneity, as the patients, pathologies, and treatments they encounter can vary greatly both within the pediatric intensive care unit and within... read more

Heterogeneity in Pediatric ARDS: Challenges and Complexities in Diagnosis and Treatment

Use of Cardiac POCUS in Diagnosis of HFrEF in a Patient with Ischemic Stroke

Ischemic strokes in younger adults, those 18 to 50 years old, account for approximately 10% to 15% of all ischemic strokes. Risk factors for stroke between younger and older patients tend to be similar. Younger patients... read more

Use of Cardiac POCUS in Diagnosis of HFrEF in a Patient with Ischemic Stroke

Pros and Cons of Disconnecting the Ventilator During Acute Respiratory Decompensation

Disconnecting the ventilator and manual BMV should be performed in cases where device malfunction is the primary cause of decompensation. These instances are quite rare. Disadvantages of switching to BMV include loss of... read more

Pros and Cons of Disconnecting the Ventilator During Acute Respiratory Decompensation

Myocarditis After COVID‐19 mRNA Vaccination in Australia

Myocarditis in adolescents and young adults following the administration of coronavirus disease 2019 (COVID‐19) mRNA vaccines has been reported. Vaccination of 12–16‐year‐old adolescents with Comirnaty (tozinameran,... read more

Myocarditis After COVID‐19 mRNA Vaccination in Australia

Postoperative Sepsis Infection Can Be Identified Using Gene Expression Signatures

Host biomarker signatures may be able to identify postoperative infection or sepsis up to three days in advance of clinical recognition. If validated in future studies, these signatures offer potential diagnostic utility... read more

Postoperative Sepsis Infection Can Be Identified Using Gene Expression Signatures

Pericarditis and Myocarditis in the ED

Chest pain is one of the most common presentations to the emergency department (ED) and includes a wide differential diagnosis. In today’s post, we will review a less common cause of chest pain seen in the ED: pericarditis... read more

Pericarditis and Myocarditis in the ED

Risks and Burdens of Incident Diabetes in Long COVID

In the post-acute phase, we report increased risks and 12-month burdens of incident diabetes and antihyperglycaemic use in people with COVID-19 compared with a contemporary control group of people who were enrolled during... read more

Risks and Burdens of Incident Diabetes in Long COVID

Epidemiology and Outcomes of Critically Ill Children at Risk for PARDS

The Pediatric Acute Lung Injury Consensus Conference “at-risk for pediatric acute respiratory distress syndrome” criteria identify critically ill children at high risk of pediatric acute respiratory distress syndrome... read more

Epidemiology and Outcomes of Critically Ill Children at Risk for PARDS

Therapeutic Hyperthermia Associated with Improved Survival in Afebrile Critically Ill Patients with Sepsis

Participants randomized to external forced-air warming did not have a difference in HLA-DR expression or IFN-γ production. In this pilot study, however, 28-day mortality was lower in the intervention group. Future research... read more

Therapeutic Hyperthermia Associated with Improved Survival in Afebrile Critically Ill Patients with Sepsis

Lung Ultrasonography Beyond the Diagnosis of Pediatrics Pneumonia

Pneumonia is a prevalent disease with considerable morbidity and mortality among the pediatric population. Early diagnosis and swift commencement of the correct treatment are vital for a favorable clinical outcome. Along... read more

Lung Ultrasonography Beyond the Diagnosis of Pediatrics Pneumonia