Textbook of Cardiorenal Medicine

This textbook provides a practical and board-driven resource to describe and define the emerging field of cardiorenal medicine. Covering all aspects of the topic with depth and relevance, this groundbreaking reference brings... read more

Textbook of Cardiorenal Medicine

Shock Indices as Prognostic Indicators: among Sepsis and Septic Shock Patients with and without Comorbidities Presenting to Emergency Department

Almost 30 million people are affected, and 3 million deaths happen every year because of sepsis. According to WHO's (World Health Organization) Global Report on Epidemiology and Burden of Sepsis report 2020, half of the... read more

Shock Indices as Prognostic Indicators: among Sepsis and Septic Shock Patients with and without Comorbidities Presenting to Emergency Department

Uncommon Diseases in the ICU

This book highlights the practical characteristics of uncommon diseases and presents the most relevant features for the management of intensive care units. It does not aim to provide an exhaustive description of uncommon... read more

Uncommon Diseases in the ICU

ICU Precision Diagnosis with Metagenomic Sequencing

Despite promising results, metagenomics remains underutilized in the ICU. Several factors still limit its inclusion in routine critical care, including the lack of definitive clinical trials testing its utility, few laboratories... read more

ICU Precision Diagnosis with Metagenomic Sequencing

Trauma, Eighth Edition

Hailed by readers and reviewers for its expert authorship and high-yield clinical content, Trauma is unquestionably the field's definitive text. Enhanced by a full-color design and a high-quality atlas of anatomic drawings... read more

Trauma, Eighth Edition

Management of RV-Predominant Heart Failure and Shock in the Cardiac ICU

Cardiogenic shock from left ventricular failure is a common presentation in the intensive care unit. In contrast, right ventricular (RV)-predominant heart failure (HF) causing shock is less well recognized. We review... read more

Management of RV-Predominant Heart Failure and Shock in the Cardiac ICU

ARDS Readmissions: A nationwide Cross-sectional Analysis of Epidemiology

Thirty-day readmission occurred in 18.4% of patients with acute respiratory distress syndrome (ARDS) in this sample, and early readmission is strongly associated with increased mortality compared to late readmission. Further... read more

ARDS Readmissions: A nationwide Cross-sectional Analysis of Epidemiology

Infection Microbiology and Management

Infection: Microbiology and Management provides a core resource for the understanding of medical microbiology and infectious diseases. Content covers microbiological and clinical diagnosis, through to clinical management,... read more

Infection Microbiology and Management

Epidemiology, Outcomes, and Trends of Patients with Sepsis and Opioid-Related Hospitalizations

Sepsis is an important cause of morbidity and mortality in patients with opioid-related hospitalizations, and opioid-related hospitalizations contribute disproportionately to sepsis-associated deaths among younger patients.... read more

Epidemiology, Outcomes, and Trends of Patients with Sepsis and Opioid-Related Hospitalizations

Quantifying the Burden of Viral Sepsis During the COVID-19 Pandemic and Beyond

Coronavirus disease 2019 (COVID-19), the disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has resulted in millions of deaths worldwide and countless more admissions to hospitals and ICUs. Since... read more

Quantifying the Burden of Viral Sepsis During the COVID-19 Pandemic and Beyond

Red Book: Report of the Committee on Infectious Diseases

Extending an 8-decade tradition of excellence, Red Book® provides the most reliable and clinically useful information on the manifestations, etiology, epidemiology, diagnosis and treatment of more than 200 childhood infectious... read more

Red Book: Report of the Committee on Infectious Diseases

Epidemiology of Functional Seizures Among Adults Treated at a University Hospital

This case-control study found evidence to support previously reported associations, discovered new associations between functional seizures and PTSD, anxiety, and depression. An association between cerebrovascular disease... read more

Epidemiology of Functional Seizures Among Adults Treated at a University Hospital

Intracerebral Hemorrhage (ICH)

For most patients, the best treatment seems to be high-quality supportive care. Aggressive interventions (e.g., causing dramatic drops in blood pressure and "prophylactic" hypertonic saline) may cause more harm than good. Cerebellar... read more

Intracerebral Hemorrhage (ICH)

Epidemiology and Costs of Sepsis in the United States

The highest burden of incidence and total costs occurred in the lowest severity sepsis cohort population. Sepsis cases not diagnosed until after admission, and those with increasing severity had a higher economic burden and... read more

Epidemiology and Costs of Sepsis in the United States

Perioperative Kidney Injury: Principles of Risk Assessment, Diagnosis and Treatment

The kidneys participate in all vital processes of the body to maintain overall homeostasis and health. When kidneys are injured during surgical interventions, metabolic and hemodynamic control is disrupted, leading to dysfunction... read more

Perioperative Kidney Injury: Principles of Risk Assessment, Diagnosis and Treatment

Against the Odds – When Statistics Fail the Patient

Do you want to cut the cord? the nurse asked. I watched my husband pick up the scissors, his hand trembling as he cautiously severed the lifeline that once connected our daughter, Anika, to me. The nurse wrapped her in a... read more

Against the Odds – When Statistics Fail the Patient

Natural History of COPD Exacerbations in a General Practice-based Population with COPD

A large proportion of patients with chronic obstructive pulmonary disease (COPD) do not exacerbate over a maximum 10 years of follow-up. AECOPD frequency in a single year predicts long-term AECOPD rate. Increasing frequency... read more

Natural History of COPD Exacerbations in a General Practice-based Population with COPD

Differences in Impact of Definitional Elements on Mortality Precludes International Comparisons of Sepsis Epidemiology

Within a sepsis cohort, we illustrate case-mix heterogeneity using definitional elements (infection source and organ dysfunction). In the context of improving outcomes, we illustrate differential secular trends in impact... read more

Differences in Impact of Definitional Elements on Mortality Precludes International Comparisons of Sepsis Epidemiology