High-Sensitivity Troponin T in a Secondary Care Setting

High-Sensitivity Troponin T in a Secondary Care Setting

High-sensitivity troponin (hs-cTn) assays play a crucial role in the early detection and management of patients with suspected acute coronary syndrome (ACS). This study supports evidence that serial troponin measurements... read more

Noninvasive Ventilation in Sleep Medicine and Pulmonary Critical Care

Noninvasive Ventilation in Sleep Medicine and Pulmonary Critical Care

This book is an introduction to a comprehensive analysis of recent advances and clinical research in noninvasive mechanical ventilation (NIV) in Pulmonary, Critical Care, and Sleep Medicine. The objective of the book is to... read more

Noninvasive Mechanical Ventilation and Difficult Weaning in Critical Care

Noninvasive Mechanical Ventilation and Difficult Weaning in Critical Care

This book establishes the indications for the use of NIV in the context of weaning from invasive mechanical ventilation. It provides a comprehensive overview of key topics relevant for correct practical application, including... read more

The ICU Book

The ICU Book

A fundamental and respected resource book in critical care, The ICU Book, continues to provide the current and practical guidance that have made it the best-selling text in critical care. The text addresses both the medical... read more

Differential Diagnosis and Cause-specific Treatment During OHCA

Differential Diagnosis and Cause-specific Treatment During OHCA

The cardiopulmonary resuscitation (CPR) guidelines recommend identifying and correcting the underlying reversible causes of out-of-hospital cardiac arrest (OHCA). However, it is uncertain how often these causes can be... read more

High-risk Pulmonary Embolism in the ICU

High-risk Pulmonary Embolism in the ICU

According to the European guidelines, high-risk pulmonary embolism (PE) is defined as PE associated with hemodynamic instability, including sustained hypotension, cardiogenic shock and/or cardiac arrest. High-risk PE... read more

Optimal Bundle of Recommendations for Sepsis

Optimal Bundle of Recommendations for Sepsis

The aim of this retrospective cohort study was to identify among the Surviving Sepsis Campaign (SSC) guidelines the optimal bundle of recommendations that minimize 28-day mortality. The bundle of six recommendations is... read more

Impact of Variations in the Nursing Care Supply-Demand Ratio on Postoperative Outcomes and Costs

Impact of Variations in the Nursing Care Supply-Demand Ratio on Postoperative Outcomes and Costs

Improving surgical outcomes is a priority during the last decades because of the rising economic health care burden. The adoption of enhanced recovery programs has been proven to be part of the solution. In this context,... read more

Spotlight on Aortic Stenosis and Dissection

Spotlight on Aortic Stenosis and Dissection

This Focus Issue on valvular heart disease contains the State of the Art Review article "ESC/EACTS vs. ACC/AHA guidelines for the management of severe aortic stenosis" by Grace Lee from the Temerty Faculty of Medicine in... read more

COVID-19 Treatment Guidelines New Version Published

COVID-19 Treatment Guidelines New Version Published

The COVID-19 Treatment Guidelines Panel (the Panel) is pleased to announce the publication of an updated version of the Coronavirus Disease 2019 (COVID-19) Treatment Guidelines. In the United States, the prevalence of... read more

Acute Effects of Ketamine on ICP in Children With Severe TBI

Acute Effects of Ketamine on ICP in Children With Severe TBI

In this retrospective, exploratory study, intracranial pressure (ICP) did not increase following ketamine administration. In the setting of a guidelines-based protocol, ketamine was associated with a reduction in ICP during... read more

House Officer’s Guide to ICU Care

House Officer’s Guide to ICU Care

Your Must-Have Guide for Navigating the ICU The House Officer's Guide to ICU Care is an eminently practical handbook for junior house officers, medical students, PAs, and nurses that offers nuts-and-bolts guidelines for optimal... read more

Perioperative Management of Antithrombotic Therapy

Perioperative Management of Antithrombotic Therapy

Substantial new evidence has emerged since the 2012 iteration of these guidelines, especially to inform best practices for the perioperative management of patients who are receiving a VKA and may require heparin bridging,... read more

Advanced Bleeding Control in Combat Casualty Care

Advanced Bleeding Control in Combat Casualty Care

Consensus was reached on the contents of a standard bleeding control toolbox, where it should be available, providers and training requirements, international registries and guidelines, and potential indications for REBOA... read more

Sedation Management Evolution in the ICU

Sedation Management Evolution in the ICU

This paper provided an overview of how ICU sedation practices have evolved over the last 20 years. Contemporary ICU sedation practices include light levels of sedation, SAT, and use of non-benzodiazepines. The current... read more

Setting up a Rescue ECLS Program

Setting up a Rescue ECLS Program

Extracorporeal life support (ECLS) is a high-risk, lifesaving medical treatment that is typically limited to centers that can support a comprehensive ECLS program. Rescue programs can bridge the gap in care between ECLS centers... read more

Damage Control in Trauma Care: An Evolving Comprehensive Team Approach

Damage Control in Trauma Care: An Evolving Comprehensive Team Approach

This book describes current, evidence-based guidelines for damage control interventions across the field of trauma care with the aim of enabling clinicians to apply them to best effect in daily clinical practice. Emphasis... read more