Leading EHR System Adopts Bundle to Prevent ICU Delirium

Seminal studies at Vanderbilt University Medical Center over the past two decades by pulmonary and critical care specialist Wes Ely, M.D. and colleagues have spurred ICU delirium research, and the resulting body of evidence... read more

Leading EHR System Adopts Bundle to Prevent ICU Delirium

Cannula and Circuit Management in Peripheral ECMO

Variable practices regarding extracorporeal membrane oxygenation (ECMO) line management exist worldwide based on recommendations lacking specific ECMO content and context. This survey identified evidence gaps regarding... read more

Cannula and Circuit Management in Peripheral ECMO

Early Identification of Patients at High Risk of Streptococcus-associated Necrotizing Infections

Two simple and available upon admission clinical predictors of group A streptococcus (GAS) documentation identified among a large cohort of surgically proven necrotizing soft tissue infections (NSTIs). The results show... read more

Early Identification of Patients at High Risk of Streptococcus-associated Necrotizing Infections

Association of Severe Hyperoxemia Events and Mortality Among Patients Admitted to a PICU

Greater numbers of severe hyperoxemia events appeared to be associated with increased mortality in this large, diverse cohort of critically ill children, supporting a possible exposure-response association between severe... read more

Association of Severe Hyperoxemia Events and Mortality Among Patients Admitted to a PICU

Guidelines for the Management of Severe TBI

Often, the available evidence is not sufficient to generate guidelines addressing the most critical questions faced by clinicians and patients. Although there have been some major developments in severe traumatic brain... read more

Guidelines for the Management of Severe TBI

Ethical Considerations About Artificial Intelligence for Prognostication in Intensive Care

New Artificial Intelligence (AI) and machine learning techniques have the potential to improve prognostication in intensive care. However, they require further refinement before they can be introduced into daily practice.... read more

Ethical Considerations About Artificial Intelligence for Prognostication in Intensive Care

Cardiac Intensive Care

Using a multidisciplinary, team-oriented approach, this unique title expertly covers all the latest approaches to the assessment, diagnosis, and treatment of patients with critical cardiac illness. Led by Dr David L. Brown,... read more

Cardiac Intensive Care

Healthcare Provider Perceptions of Cardiopulmonary Resuscitation Quality During Simulation Training

Cardiopulmonary resuscitation performance during mock codes does not meet the American Heart Association's quality recommendations. Healthcare providers have poor insight into the quality of cardiopulmonary resuscitation... read more

Healthcare Provider Perceptions of Cardiopulmonary Resuscitation Quality During Simulation Training

What Should You Know About Evidence-Based Guidelines?

As healthcare professionals we want to provide patients the best possible medical care. Prehospital care, like the rest of medicine, is constantly changing, since the research performed today will shape the medical care we... read more

Impact of Delayed Admission to ICUs on Mortality of Critically Ill Patients

When the number of patients who require intensive care is greater than the number of beds available, intensive care unit (ICU) entry flow is obstructed. This phenomenon has been associated with higher mortality rates... read more

Impact of Delayed Admission to ICUs on Mortality of Critically Ill Patients

Myocardial Ischemia During Ventilator Weaning

This observational study showed the pulmonary edema (WiPO) occurred in a significant number of critically ill patients who failed a first spontaneous breathing trial (SBT), while cardiac ischemia (WiCI) was less frequent.... read more

Myocardial Ischemia During Ventilator Weaning

Sedation is Necessary to Minimize Patients’ Discomfort During Mechanical Ventilation

More than half of critical care nurses believe sedation is needed to minimize discomfort and distress among patients receiving mechanical ventilation, according to survey results published recently in the American Journal... read more

Sedation is Necessary to Minimize Patients’ Discomfort During Mechanical Ventilation

Adjunctive Corticosteroid Treatment in Septic Shock

Interest in the role of the adrenal cortex in the recovery from an infection dates back nearly 100 yr. More than six decades of research on the role of corticosteroid supplementation as an adjunctive treatment for sepsis... read more

Adjunctive Corticosteroid Treatment in Septic Shock

How to Optimize the Use of Blood Cultures for the Diagnosis of Bloodstream Infections?

Bloodstream infection (BSI) is a major cause of death in developed countries and the detection of microorganisms is essential in managing patients. Despite major progress has been made to improve identification of microorganisms,... read more

How to Optimize the Use of Blood Cultures for the Diagnosis of Bloodstream Infections?

Sedation Practices of Neonates Receiving ECMO

Neonatal sedation practices during extracorporeal membrane oxygenation (ECMO) are not well described and no universal guidelines exist. Current literature describes types of medications used in adult and pediatric ECMO... read more

Sedation Practices of Neonates Receiving ECMO

Outcome After Out-of-Hospital Ventricular Fibrillation or Pulseless Ventricular Tachycardia

Survival was found to be at the upper range of the results retrieved by the systematic literature review. However, we found no significant improvements over time. The neurological outcomes of the survivors were favorable.... read more

Outcome After Out-of-Hospital Ventricular Fibrillation or Pulseless Ventricular Tachycardia

The Role of Central Venous Oxygen Saturation (ScvO2) as an Indicator of Blood Transfusion in the Critically Ill

Transfusion of red blood cells is an everyday practice in critical care with the primary aim of restoring adequate tissue oxygenation. However, blood transfusion may also be harmful and costly, therefore a so called restrictive... read more

The Role of Central Venous Oxygen Saturation (ScvO2) as an Indicator of Blood Transfusion in the Critically Ill

Essentials of Mechanical Ventilation

The acclaimed application-based guide to adult mechanical ventilation, updated to reflect the latest topics and practice guidelines. This practical guide is written from the perspective of authors who have nearly 100 years'... read more

Essentials of Mechanical Ventilation