Guidelines for the Management of Tracheal Intubation in Critically Ill Adults

These guidelines describe a comprehensive strategy to optimize oxygenation, airway management, and tracheal intubation in critically ill patients, in all hospital locations. They are a direct response to the 4th National... read more

Guidelines for the Management of Tracheal Intubation in Critically Ill Adults

Predictors of In-Hospital Mortality After RRT Calls

Despite wide adoption of rapid response teams across the United States, predictors of in-hospital mortality for patients receiving rapid response team calls are poorly characterized. Identification of patients at high risk... read more

Predictors of In-Hospital Mortality After RRT Calls

Very high intact-protein formula successfully provides protein intake according to nutritional recommendations in overweight critically ill patients

Enteral feeding with VHPF (8 g/100 kcal) resulted in higher protein intake and plasma amino acid concentrations than an isocaloric SHPF (5 g/100 kcal), without an increase in energy intake. This VHPF facilitates feeding according... read more

Very high intact-protein formula successfully provides protein intake according to nutritional recommendations in overweight critically ill patients

Sepsis Guidelines Spark EM Petition

It took all of one day for emergency physicians to organize opposition after an update to the Surviving Sepsis Campaign Bundle was released online. The day after the new version was released, Scott D. Weingart, MD, the editor-in-chief... read more

Sepsis Guidelines Spark EM Petition

The Relationship Between ICU Hypotension and In-hospital Mortality and Morbidity in Septic Patients

Current guidelines recommend maintaining a mean arterial pressure (MAP)≥ 65 mmHg in septic patients. However, the relationship between hypotension and major complications in septic patients remains unclear. We, therefore,... read more

The Relationship Between ICU Hypotension and In-hospital Mortality and Morbidity in Septic Patients

Sepsis patients treated and released from emergency departments do well with outpatient follow-up

National guidelines assume that all patients who're diagnosed with clinical sepsis in an emergency department will be admitted to the hospital for additional care, but new research has found that many more patients are being... read more

Sepsis patients treated and released from emergency departments do well with outpatient follow-up

Petition to Retire the Surviving Sepsis Campaign Guidelines

Concern regarding the Surviving Sepsis Campaign (SSC) guidelines dates back to their inception. Guideline development was sponsored by Eli Lilly and Edwards Life Sciences as part of a commercial marketing campaign. Throughout... read more

Petition to Retire the Surviving Sepsis Campaign Guidelines

Mechanical Ventilation: Physiological and Clinical Applications

Known for its simple explanations and in-depth coverage of patient-ventilator management, this evidence-based text walks readers through the most fundamental and advanced concepts surrounding mechanical ventilation and guides... read more

Mechanical Ventilation: Physiological and Clinical Applications

Guideline for Reversal of Antithrombotics in Intracranial Hemorrhage

This guideline provides timely, evidence-based reversal strategies to assist practitioners in the care of patients with antithrombotic-associated intracranial hemorrhage. Utilizing the GRADE methodology, the committee developed... read more

Guideline for Reversal of Antithrombotics in Intracranial Hemorrhage

What’s Your Doctor Reading? How Social Media is Disrupting Medical Education

Traditionally, research would be presented at conferences, discussed at meetings, and gradually incorporated into international guidelines and textbooks. It would then filter down into clinical practice, years after its original... read more

Early Mobilization of Patients in ICU

Currently there is a divide between ICU clinicians who wish to implement early mobilization based on current evidence and clinicians who believe that early mobilization is an intervention that should be tested in a large... read more

Early Mobilization of Patients in ICU

How to Run Successful Rounds in the ICU

Rounds in the intensive care unit (ICU) allow for scheduled discussions in which healthcare providers review clinical information and develop care plans for critically ill patients. Despite this straightforward concept, there... read more

How to Run Successful Rounds in the ICU

Tracheotomy in the ICU: Guidelines from a French Expert Panel

Tracheotomy is widely used in intensive care units (ICUs), albeit with great disparities between medical teams in terms of frequency and modality. Indications and techniques are, however, associated with variable levels of... read more

Tracheotomy in the ICU: Guidelines from a French Expert Panel

Noninvasive Ventilation in Patients With Do-Not-Intubate and Comfort-Measures-Only Orders

A large proportion of patients with do-not-intubate orders who received noninvasive ventilation survived to hospital discharge and at 1 year, with limited data showing no decrease in quality of life in survivors. Provision... read more

Noninvasive Ventilation in Patients With Do-Not-Intubate and Comfort-Measures-Only Orders

Comparison of Self-Reported and Behavioral Pain Assessment Tools in Critically Ill Patients

Self-reported and behavioral pain assessment scales are often used interchangeably in critically ill patients due to fluctuations in mental status. The correlation between scales is not well elucidated. The purpose of this... read more

Comparison of Self-Reported and Behavioral Pain Assessment Tools in Critically Ill Patients

Tracheal Intubation During Adult In-Hospital Cardiac Arrest and Survival

This cohort study uses data from the Get With The Guidelines-Resuscitation registry to investigate the association between tracheal intubation during adult in-hospital cardiac arrest and survival to hospital discharge. In... read more

Tracheal Intubation During Adult In-Hospital Cardiac Arrest and Survival

Guidelines for Tracheal Intubation in Critically Ill Adults

The Intensive Care Society, Faculty of Intensive Care Medicine, Difficult Airway Society and the Royal College of Anesthetists have combined to provide the "Guidelines for the management of tracheal intubation in critically... read more

R.E.B.E.L. EM – Fluid Responsiveness and the Six Guiding Principles of Fluid Resuscitation

Fluid resuscitation is a crucial aspect of emergency and critical care. Since the advent of the concept of early goal-directed therapy, we have placed a huge emphasis on aggressive fluid resuscitation in patients with severe... read more

R.E.B.E.L. EM – Fluid Responsiveness and the Six Guiding Principles of Fluid Resuscitation

Managing Sepsis and Septic Shock Current Guidelines and Definitions

While sepsis defies simple definition, it's generally understood to be a clinical syndrome caused by infection that may have profound adverse physiologic consequences. Although its precise incidence is unknown, sepsis is... read more

Managing Sepsis and Septic Shock Current Guidelines and Definitions

Factors Associated with Life-Sustaining Treatment Restriction in the ICU

Few previous studies have investigated associations between clinical variables available after 24 hours in the ICU and decisions to restrict life-sustaining treatment. The aim of this study was to identify factors associated... read more

Factors Associated with Life-Sustaining Treatment Restriction in the ICU

Ultrasonography in Trauma: a Nation-wide Cross-Sectional Investigation

The Focused Assessment with Sonography in Trauma (FAST) protocol is considered beneficial in emergent evaluation of trauma patients with blunt or penetrating injury and has become integrated into the Advanced Trauma Life... read more

Ultrasonography in Trauma: a Nation-wide Cross-Sectional Investigation

The ADRENAL Trial: Steroids in Septic Shock

Randomized clinical trials evaluating the efficacy of adjunctive corticosteroids in septic shock have shown conflicting evidence of clinical relevance. Two trials in particular looked at lower dose hydrocortisone (200mg/day)... read more

The ADRENAL Trial: Steroids in Septic Shock