Difficult Bag-Mask Ventilation in Critically Ill Children Is Independently Associated With Adverse Events

Difficult bag-mask ventilation is reported in approximately one in 10 PICU patients undergoing tracheal intubation. Given its association with adverse procedure–related events and oxygen desaturation, future study is warranted... read more

Difficult Bag-Mask Ventilation in Critically Ill Children Is Independently Associated With Adverse Events

How I Approach Weaning from Venoarterial ECMO

Weaning from VA-ECMO remains a challenging but critically important step in device management. The key is to balance minimizing complications associated with device support with the potential for hemodynamic deterioration... read more

How I Approach Weaning from Venoarterial ECMO

Corticosteroids for Critically Ill COVID-19 Patients with Cytokine Release Syndrome

Approximately 5% of coronavirus disease (COVID-19) patients will require admission to an intensive care unit (ICU). Among these patients, the most severe cases may be mediated by a late-onset systemic inflammatory response... read more

Corticosteroids for Critically Ill COVID-19 Patients with Cytokine Release Syndrome

Effects of Paracentesis on Hemodynamic Parameters and Respiratory Function in Critically Ill Patients

Paracentesis in critically ill patients is safe regarding hemodynamic function, renal function and intervention-related complications. Furthermore, paracentesis in critically ill and mechanically ventilated patients results... read more

Effects of Paracentesis on Hemodynamic Parameters and Respiratory Function in Critically Ill Patients

Clinical Distancing of Patients with Advanced Heart Failure and Cardiac Transplantation During COVID-19

Our hospital system includes a central 825-bed, short term, acute care teaching facility where heart transplantation is performed under regulatory approval. Located 5.5 miles north of this main campus is a 107-bed cardiac... read more

Clinical Distancing of Patients with Advanced Heart Failure and Cardiac Transplantation During COVID-19

The End-expiratory Occlusion Test

There is growing evidence that the end-expiratory occlusion (EEO) test reliably detects preload responsiveness. It is easier to perform than passive leg raising and has less limitations than pulse pressure variations, provided... read more

The End-expiratory Occlusion Test

Fast Facts for the Critical Care Nurse

This newly updated, quick-access guide for critical care nurses covers the most common admitting diagnoses and reviews their causes, signs and symptoms, and interventions. Critical care nursing requires astute assessment,... read more

Fast Facts for the Critical Care Nurse

Comparison of Echocardiographic and Invasive Measures of Volaemia and Cardiac Performance in Critically Ill Patients

Static echocardiographic variables did not reliably reflect the volume state as defined by estimates of mean systemic filling pressure. There was no statistical or clinically robust relationship between static echocardiographic... read more

Comparison of Echocardiographic and Invasive Measures of Volaemia and Cardiac Performance in Critically Ill Patients

Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children

A large cohort of international experts was able to achieve consensus regarding many recommendations for the best care of children with sepsis, acknowledging that most aspects of care had relatively low quality of evidence... read more

Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children

Artificial Intelligence or Merely a Symptom of a Broken Healthcare System?

We are constantly hunting for newer and better sources of information. This leads to a perpetual generation of newer lab tests, different hemodynamic gizmos, and fresh decision tools. Some of these pan out. Most don't. Why... read more

Artificial Intelligence or Merely a Symptom of a Broken Healthcare System?

Microcirculation Evolution in Patients on VA-ECMO for Refractory Cardiogenic Shock

Microcirculation is severely impaired in patients with refractory cardiogenic shock requiring venoarterial extracorporeal membrane oxygenation (VA-ECMO). Inability to rapidly restore microcirculation during the first... read more

Microcirculation Evolution in Patients on VA-ECMO for Refractory Cardiogenic Shock

Vasopressin for Acute Hemorrhage?

Vasoactive medications are one of the pillars of management of shock in Emergency Departments. Inopressors, namely Norepinephrine and Epinephrine, are the two most commonly used pressors in US Emergency Departments, used... read more

Vasopressin for Acute Hemorrhage?

Predicting Adverse Hemodynamic Events in Critically Ill Patients

The art of predicting future hemodynamic instability in the critically ill has rapidly become a science with the advent of advanced analytical processed based on computer-driven machine learning techniques. How these... read more

Predicting Adverse Hemodynamic Events in Critically Ill Patients

The Neurohormonal Basis of Pulmonary Hypertension in HFpEF

Subjects with heart failure with preserved ejection fraction (HFpEF) display activation of the endothelin and adrenomedullin neurohormonal pathways, the magnitude of which is associated with pulmonary hemodynamic derangements,... read more

The Neurohormonal Basis of Pulmonary Hypertension in HFpEF

Nonoperative Management of Splenic Injury of Patients with Reduced Consciousness is Safe and Feasible in Well-equipped Institutions

This study shows that NOM for blunt splenic trauma is a viable treatment modality in well-equipped institutions, regardless of the patients mental status. However, the presence of neurologic impairment is associated with... read more

Nonoperative Management of Splenic Injury of Patients with Reduced Consciousness is Safe and Feasible in Well-equipped Institutions

Ultrasound-based Clinical Profiles for Predicting the Risk of Intradialytic Hypotension in Critically Ill Patients on Intermittent Dialysis

In critically ill patients on intermittent hemodialysis, the absence of hypervolemia as assessed by lung and vena cava ultrasound predisposes to intradialytic hypotension and suggests alternative techniques of hemodialysis... read more

Ultrasound-based Clinical Profiles for Predicting the Risk of Intradialytic Hypotension in Critically Ill Patients on Intermittent Dialysis

Adaptive Mechanical Ventilation with Automated Minimization of Mechanical Power

Adaptive mechanical ventilation with automated minimization of inspiratory power may lead to more lung-protective ventilator settings when compared with adaptive mechanical ventilation according to Otis' equation. Comparing... read more

Adaptive Mechanical Ventilation with Automated Minimization of Mechanical Power

Pulmonary Artery Catheters for Adult Patients in ICU

Pulmonary Artery Catheters (PAC) is a diagnostic and haemodynamic monitoring tool but not a therapeutic intervention. Our review concluded that use of a PAC did not alter the mortality, general ICU or hospital LOS, or cost... read more

Pulmonary Artery Catheters for Adult Patients in ICU

Practical Trends in Anesthesia and Intensive Care 2018

This book offers an essential guide to managing the most-debated hot topics of practical interest in anesthesia and intensive care. It reviews the state of the art in issues concerning both intensive care medicine and anesthesia,... read more

Practical Trends in Anesthesia and Intensive Care 2018

Using Additional Pressure Control Lines When Connecting a Continuous RRT Device to an ECMO Circuit

The present study suggests that the use of additional tubing can be considered a simple and safe method for pressure control and improvement of filter survival when connecting a continuous renal replacement therapy (CRRT)... read more

Using Additional Pressure Control Lines When Connecting a Continuous RRT Device to an ECMO Circuit

Snapshots of Hemodynamics

This new edition reviews recent developments in genetics and molecular biology and new noninvasive measurement techniques that have enabled vast improvements in the measurement and understanding of cardiovascular hemodynamics.... read more

Snapshots of Hemodynamics