Temporal Trends of RSV-Associated US ICU Admissions

Wide variations in regional and seasonal patterns in hospital and ICU admissions were noted in children with respiratory syncytial virus–associated acute respiratory illness across the United States. Results from our... read more

Non-invasive Mechanical Ventilation in Critical Care, Anesthesiology and Palliative Care

This book provides an easy, modern and practical way for physicians to approach the world of noninvasive mechanical ventilation (NIMV). Noninvasive ventilation is well-established and increasingly used in routine clinical... read more

Non-invasive Mechanical Ventilation in Critical Care, Anesthesiology and Palliative Care

The ICU Survival Book

The ICU Survival Book is a guide for residents, students, advanced practice providers, and critical care nurses who want to learn the basics of critical care medicine. This reference is designed to follow the systems-based... read more

The ICU Survival Book

Intubating the Critically Ill Patient: A Step-by-Step Guide for Success in the ED and ICU

Intubating critically ill patients is a process that requires a well-thought-out, step-by-step plan, specific to each patient. This book teaches the steps necessary to predict, prepare, perform, and provide pre and post-intubation... read more

Intubating the Critically Ill Patient: A Step-by-Step Guide for Success in the ED and ICU

IFG vs. CBG in Patients with Multiple Organ Failure Requiring Vasopressor Infusion

Interstitial flash glucose (IFG) does not demonstrate either analytical or clinical accuracy to be considered equivalent to capillary blood glucose (CBG) in patients with multiple organ failure who require vasopressor infusion. This... read more

Prediction of AKI in ICU Patients Based on Interpretable Machine Learning

The machine learning model described in this study is capable of accurately predicting the onset of AKI in ICU patients up to 24 hours in advance. Validated within the MIMIC-IV and MIMIC-III databases, the model demonstrates... read more

Intubate Patients with Sepsis Before Midnight or When the Time Comes?

The ever-recurring decision for every clinician is to act or not to act and when to act. The balance of benefit or harm of an intervention and the optimal timing of treatment is not always clear. Intervening or not and... read more

Does AI Close Gaps in Clinical Pharmacology in the ICU?

Artificial intelligence (AI) has the potential to close significant gaps in clinical pharmacology in the ICU. Its applications range from personalized dosing and predictive analytics to clinical trial optimization and education.... read more

Leveraging the Power of Routinely Collected ICU Data

With the steady advent of electronic health records, the abundance of routinely recorded data related to the treatment and care of intensive care unit (ICU) patients can be nothing short of overwhelming. Over tens of... read more

Fluid Bolus Therapy with 20% Albumin vs. Crystalloid-based Regimen

In this trial involving adult patients undergoing cardiac surgery with cardiopulmonary bypass, 20% albumin fluid bolus therapy (FBT) compared to crystalloid FBT did not decrease the occurrence of acute kidney injury (AKI).... read more

New Insights on CRRT for ARDS

In recent times, the applications of continuous renal replacement therapy (CRRT) beyond kidney‐related conditions have been progressively increasing, and its implementation in randomized controlled trials (RCTs) specifically... read more

Single-use vs. Multiple-use Endotracheal Suction Catheters Flushed with Chlorhexidine in Mechanically Ventilated ICU Patients

The aim of this feasibility randomized controlled trial (fRCT) is to assess the practicality and impact of using single-use versus multiple-use endotracheal suction catheters flushed with chlorhexidine on the incidence of... read more

Immune Cell-Based vs. Albumin-Based Ratios as Outcome Predictors in Critically Ill COVID-19 Patients

This study aimed to assess the prognostic value of an array of biomarkers regarding the likelihood of a lethal outcome in critically ill COVID-19 patients. We took advantage of the opportunity to classify them into immune... read more

Invasive Mechanical Ventilation Strategies For ICU Patients with COVID-19

Lung protective ventilation and prone positioning were used in many of the Danish ICU patients with COVID-19, but barotrauma, prolonged ventilation and death occurred frequently. A total of 774 patients were invasively... read more

Passport to Successful Outcomes for Patients Admitted to ICU: Meeting Patient Goals of Care

The second edition builds upon the previous content, exploring new and emerging evidence to enhance the structure and content of rehabilitation provided. It considers the additional impact of COVID-19 throughout each chapter.... read more

Passport to Successful Outcomes for Patients Admitted to ICU: Meeting Patient Goals of Care

7-day Fluid Balance Associated with Poor Outcomes

The net fluid balance in patients with sepsis 7 days following ICU administration was significantly related to mortality during hospitalization. Specifically, a 7-day fluid balance > 5,240 mL was associated with poor... read more

Establishment and Validation of a Risk Prediction Model for Sepsis-Associated Liver Injury in ICU Patients

This novel nomogram effectively predicts SALI risk in sepsis patients by integrating readily available clinical parameters. While external validation is needed, the model shows promise as a practical tool for early risk stratification,... read more

Lactic Acidosis with Metformin Accumulation in the ICU

Metformin-associated lactic acidosis (MALA) in ICUs often follow acute dehydration or infection, and these high-risk situations must be signals to prevent this serious ADR. Specific education programs for physicians and... read more

Increased Lactate Dehydrogenase to Albumin Ratio Associated with Short-term Mortality in Septic ICU Patients

Elevated lactate dehydrogenase to albumin ratio (LAR) was found to be significantly associated with an increased risk of all-cause mortality at 28 and 90 days in septic patients. LAR was suggested to be promising biomarker... read more