Another Perspective on Tidal Volume: From Statistics to Uncertainty

We have read with great interest the recent editorial by Pellegrini et al. Undoubtedly, now more than ever, we have begun to question the true role of tidal volume (VT) in acute respiratory distress syndrome (ARDS). As... read more

Secretomic Approach Value in COVID-19 Viral Pneumonia Among Patients With Respiratory Distress

this article presents an innovative and promising secretomic analysis to distinguish VPP patients from NV-ICU patients using combinations of protein markers. Among the identified proteins, ficolin-3 and proteoglycan-4 appear... read more

Critical Care Companion: Your Guide To ICU Nursing

Step into the dynamic and demanding world of Intensive Care Unit (ICU) nursing with Critical Care Companion: Your Guide to ICU Nursing by Alysha Edwards. This indispensable guide is crafted to support both novice and experienced... read more

Critical Care Companion: Your Guide To ICU Nursing

Emergency Department Disposition and Mortality in COVID‐19 Patients with ARDS

Compared to direct ICU admission, admission from the ED to the ward is associated with increased mortality in patients who meet COVID‐19 ARDS criteria during their hospitalization, despite lower 4C and similar SAPS‐III... read more

Endothelial Dysfunction and Persistent Inflammation in Severe Post-COVID-19 Patients

Six months after ICU discharge from severe ARDS secondary to COVID-19, patients with gas exchange impairment exhibit evidence of systemic inflammation, along with elevated ICAM-1 levels, ultimately resulting in increased... read more

Cardiac Arrest During a Ferric Derisomaltose Infusion Followed by Complete Heart Block

Bradycardia and heart block are rarely reported in the parenteral iron literature. Although rare, it may be reasonable to consider parenteral iron as a toxicological etiology for patients presenting with complete heart block... read more

Weaning From Mechanical Ventilation in ICUs Across 50 Countries

Current management practices and outcomes in weaning from invasive mechanical ventilation are poorly understood. We aimed to describe the epidemiology, management, timings, risk for failure, and outcomes of weaning in patients... read more

Early In-Bed Cycle Ergometry in Mechanically Ventilated Patients

Among adults receiving mechanical ventilation in the ICU, adding early in-bed Cycling to usual physiotherapy did not improve physical function at 3 days after discharge from the ICU compared with Usual physiotherapy alone.... read more

Secretomic Approach Value for Distinguishing Patients with COVID-19 Viral Pneumonia Among ICU Patients with Respiratory Distress

In intensive care units, COVID-19 viral pneumonia patients (VPP) present symptoms similar to those of other patients with Nonviral infection (NV-ICU). To better manage VPP, it is therefore interesting to better understand... read more

Early vs. Delayed Enteral Nutrition in ICU Sepsis Patients

Early enteral nutrition may not affect mortality rates when analyzed using propensity score matching. However, our findings indicate that early enteral nutrition is associated with shorter ICU stays and a lower incidence... read more

Immunosuppression Not Associated with a Higher Incidence of ICU-acquired Bacterial Bloodstream Infections

In this monocentric, retrospective observational cohort study, the incidence of ICU-acquired bacterial BSI was not different between immunocompromised and non-immunocompromised patients. This suggests that the clinical... read more

Incidence of AKI and attributive mortality in ARDS randomized trials

The development of acute kidney injury (AKI) after the acute respiratory distress syndrome (ARDS) reduces the chance of organ recovery and survival. The purpose of this study was to examine the AKI rate and attributable mortality... read more

Improving Spontaneous Breathing Trials With a Respiratory Therapist-Driven Protocol

This quality improvement (QI) project aimed to standardize and re-establish RT-driven protocol for screening patients for SBT readiness and administering SBTs to appropriate patients. Endotracheally intubated and mechanically... read more

Hepatorenal Syndrome in the ICU

Patients with cirrhosis are susceptible to develop acute kidney injury (AKI), a complication that occurs in up to 50% of hospitalized patients [80% in the intensive care unit (ICU)], and has been associated with increased... read more

Sepsis Mortality Among ICU Patients with Hematological Malignancy

Over the past two decades, there have been substantial improvements in mortality in hematological malignancy patients with sepsis, including across all levels of illness severity and in patients requiring mechanical ventilation.... read more

Impact of a Rounding Checklist Implementation in the Trauma ICU on Clinical Outcomes

We aimed to evaluate the effectiveness of an intensive care unit (ICU) round checklist, FAST HUGS BID (Feeding, Analgesia, Sedation, Thromboembolic prophylaxis, Head-of-bed elevation, Ulcer prophylaxis, Glycemic control,... read more

Cardiac Index and Heart Rate as Prognostic Indicators for Mortality in Septic Shock

Our retrospective study shows that monitoring cardiac index and heart rate in patients with septic shock may help predict the organismal response and hemodynamic consequences, as well as the prognosis. Thus, healthcare providers... read more

Scientific Study Validates Usability of Post-ICU Digital Diary for Families of ICU Patients

In a groundbreaking pilot study, "The usability of a digital diary from the perspectives of intensive care patients’ relatives", researchers have unequivocally confirmed the practicality and effectiveness of Post-ICU for... read more

AKI Risk Factors in ICU Patients Using Colistin

Colistin, an antibiotic of polymyxin group, has recently been increasingly used in the treatment of multidrug resistant gram-negative bacteria. However, it has serious adverse effects such as acute kidney injury (AKI). We... read more

COVID-19 Airway Management and Ventilation Strategy for Critically Ill Older Patients

This book describes the issues and challenges that clinicians encountered in the management of older critically ill patients during the COVID-19 pandemic, and offers practical information on how to manage them. Older... read more

COVID-19 Airway Management and Ventilation Strategy for Critically Ill Older Patients

VTE in Critically Ill Adult Patients with Hematologic Malignancy

Among patients with hematologic malignancy, critical illness and certain baseline characteristics were associated with a higher incidence of venous thromboembolism (VTE). Among 76,803 eligible patients (mean age 67 years... read more

Haloperidol vs. Placebo in ICU Patients with Delirium

We assessed long-term outcomes in acutely admitted adult patients with delirium treated in intensive care unit (ICU) with haloperidol versus placebo. In acutely admitted adult ICU patients with delirium, haloperidol treatment... read more