Tag: ICU
Fluid boluses and infusions in the early phase of resuscitation from septic shock and sepsis-induced hypotension
Fluid administration is the first line treatment in intensive care unit (ICU) patients with sepsis and septic shock. While fluid boluses administration can be titrated by predicting preload dependency, the amount of other... read more
Longitudinal Vasoactive Inotrope Score Trajectories and Their Prognostic Significance in Critically Ill Sepsis Patients
This study offers significant insights into the prognostic value of VIS trajectories in sepsis patients. The identification of distinct trajectory patterns not only underscores the heterogeneity in sepsis but also emphasizes... read more
Factors Affecting the Duration of Hospitalization in Urology and Nephrology Patients in the ICU
Factors affecting ICU stay length in Urology and Nephrology patients who required close monitoring and specialized medical staff were investigated. The study found a positive association between prolonged ICU stays and elevated... read more
Ventilator-associated Pneumonia Risk Factors in Patients with Severe COVID-19
Patients with COVID-19 are at high risk of VAP, which may be related to issues other than prolonged mechanical ventilation (MV) time. Multiple factors increase the chances of these patients developing VAP, including:... read more
Prevalence and Risk Factors of ICU-acquired Weakness in COVID-19 Patients
The prevalence of ICUAW in patients with COVID-19 was considered relatively high. Older age, pre-existing hypertension, medical intervention of prone position, NMBA use, needed tracheostomy and RRT were likely risk factors.... read more
Pressure Support Ventilation During ECMO Support in Patients with ARDS
In the initial phases of veno-venous extracorporeal membrane oxygenation (VV ECMO) support for severe acute respiratory distress syndrome (ARDS), ultraprotective controlled mechanical ventilation (CMV) is typically employed... read more
Outcomes for Mechanically Ventilated Patients with Acute Myocardial Infarction Admitted to Medical vs Cardiac ICUs
In this multicenter, national analysis of ICU admission for critically ill patients with AMI, we found that admission to the Cardiac Intensive Care Unit (CICU) was associated with lower in-hospital mortality than patients... read more
Emergency and Prophylactic ECMO for Patients Undergoing Valve-in-Valve Transcatheter Aortic Valve Implantation with Small Surgical Bioprosthesis
Mechanical circulatory support (MCS) using veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is widely implemented as a rescue device in transcatheter aortic valve implantation (TAVI). Although prophylactic... read more
Device Associated Complications in the ICU
Although mortality in the intensive care unit (ICU) has declined over time, ICU associated complications remain common, affecting up to a half of critically ill patients and resulting in increased mortality, longer hospital... read more
How to end quiet suffering in the ICU? Identifying and treating hypoactive delirium
The duration of time a person spends in hypoactive delirium predicts higher rates of death, longer length of stay, higher costs of care, and higher rates of acquired dementia in the months and years following critical illness.... read more
Risk Factors for Mortality in Patients with Sepsis or Sepsis-associated Delirium Based on the MIMIC-IV Database
Research on the severity and prognosis of sepsis with or without progressive delirium is relatively insufficient. We constructed a prediction model of the risk factors for 28-day mortality in patients who developed sepsis... read more
Withholding Early Parenteral Nutrition on 2-year Mortality in Critically Ill Adults
Late-PN did not alter 2-year survival and physical functioning in adult critically ill patients, independent of anticipated nutritional risk. In this prospective follow-up study of the multicenter EPaNIC randomized controlled... read more
BPRI and Clinical Outcomes in Patients with Septic Shock
Use of the novel dose-effect index, Blood Pressure Response Index (BPRI) was proposed to allow rapid bedside assessment of the reactivity of septic shock patients to vasoactive drugs, as isolated MAP or VIS cannot reflect... read more
AI to Predicting Mortality Risk in ICU Patients with AKI
To address the limitations of early acute kidney injury (AKI) prediction, researchers have increasingly turned to machine learning methods. However, the success of these models hinges on the selection of relevant features.... read more
Fluid Accumulation Syndrome in Sepsis and Septic Shock
In this review, we aimed to comprehensively summarize current literature on pathophysiology, relevance, diagnosis and treatment of fluid accumulation in patients with sepsis/septic shock. Fluid accumulation syndrome (FAS)... read more
Lower or Higher Oxygenation Targets in the ICU
This study reported no overall differences comparing a PaO2 target of 8–12 kPa on mortality or days alive without life support in 90 days. Subgroup analyses suggested heterogeneity of treatment effects (HTE) in patients... read more
The Hidden Value of MRI: Modifying Treatment Decisions in C-spine Injuries
This study provides a critical evaluation of the implications of additional magnetic resonance imaging (MRI) use in the diagnosis of c-spine injuries. We have demonstrated that an adjunctive MRI extends patients' ED stays,... read more
Neurocritical Care for the Advanced Practice Clinician
By utilizing a review of case-based studies and providing concise management recommendations from leaders in the field, this book provides essential knowledge for those practicing in a dynamic specialty. In the rapidly... read more
Complex Infusion Volumes Interaction and Confounding Factors with Lactate Clearance in Septic Shock
A recent article by Ahlstedt et al. published in Intensive Care Medicine examining the impact of restrictive fluid management on lactate clearance in septic shock patients within the intensive care unit (ICU) piqued our interest.... read more
Sepsis Alert Systems, Mortality, and Adherence in Emergency Departments
This systematic review and meta-analysis demonstrated the significant association of implementing sepsis alert systems in the Emergency Departments (ED) with patient outcomes. These findings indicate that sepsis alert... read more
Treatment of Refractory Cardiac Arrest by Controlled Reperfusion of the Whole Body
This multicenter, prospective, all-comers observational study has provided preliminary data on a new approach to treat patients with prolonged refractory CA and CCPR by applying an advanced extracorporeal perfusion circuit,... read more
Antifungal Prophylaxis of COVID-19 Associated Pulmonary Aspergillosis in Ventilated Patients
This study investigated the impact of POSA prophylaxis on risk of CAPA development in mechanically ventilated COVID-19 patients receiving corticosteroids. We observed a significant variation in CAPA incidence rates among... read more





