Tag: ICU
Prone vs. Supine Position Ventilation in Intubated COVID-19 Patients
Whether prone positioning of patients undergoing mechanical ventilation for COVID-19 pneumonia has benefits over supine positioning is not clear. We conducted a systematic review with meta-analysis to determine whether prone... read more
The ICU Book
A fundamental and respected resource book in critical care, The ICU Book, continues to provide the current and practical guidance that have made it the best-selling text in critical care. The text addresses both the medical... read more
Significant Persistent Pain Symptoms After Critical Care Illness
Persistent pain could be a common health problem after critical illness care. Our data also suggest that there is a lack of specific follow-up after ICU discharge. Given the major consequences on patient quality of life,... read more
Cardiovascular Subphenotypes in ARDS
Latent class analysis (LCA) of transthoracic echocardiography (TTE) parameters identified four cardiovascular subphenotypes in acute respiratory distress syndrome (ARDS) that more closely aligned with circulatory failure... read more
Heparin-induced Thrombocytopenia in the Intensive Care Setting
Heparin-induced thrombocytopenia (HIT) is a serious iatrogenic complication of heparin treatments. The diagnosis of HIT is difficult in the intensive care setting because thrombocytopenia is a frequent and multifactorial... read more
Heterogeneous Treatment Effects of Therapeutic-Dose Heparin in Patients Hospitalized for COVID-19
Randomized clinical trials (RCTs) of therapeutic-dose heparin in patients hospitalized with COVID-19 produced conflicting results, possibly due to heterogeneity of treatment effect (HTE) across individuals. Better understanding... read more
Family Centered Care At The EOL in the ICU
In the context of end-of-life (EOL) care in the intensive care unit (ICU), recent research has often focussed on patients' families. Studies have shown the importance of communication between ICU clinicians and families,... read more
Predicting Deterioration of Sepsis Patients Using Continuous HVR Analysis
We showed that continuous electrocardiograms (ECG) recordings can be automatically analyzed and used to extract heart rate variability (HRV) features associated with clinical deterioration in sepsis. The predictive accuracy... read more
High-risk Pulmonary Embolism in the ICU
According to the European guidelines, high-risk pulmonary embolism (PE) is defined as PE associated with hemodynamic instability, including sustained hypotension, cardiogenic shock and/or cardiac arrest. High-risk PE... read more
Positive or Negative Prognostic Factor for Epidural Hematoma?
To our best knowledge, a typical epidural hematoma (EDP) prognosis is good if it is discovered quickly and managed. Therefore the presence of EDH is considered a positive prognostic sign in the Rotterdam, Stockholm, and the... read more
Postextubation Complications vs. Positive-Pressure Suctioning Techniques
Currently available studies that compared post-extubation complications in subjects managed with the positive-pressure and suctioning techniques were summarized. Further high-quality studies with a robust study design and... read more
Emergency Department Crowding Impact on Lung Protective Ventilation
Obtaining definitive control of the airway, when indicated, is the responsibility of the emergency medicine physician. Traditionally patients were managed on the ventilator with lung volumes of 10 – 15 ml/kg. However,... read more
Haloperidol vs. Placebo for Delirium Treatment in ICU Patients
We found high probabilities of benefits and low probabilities of harm with haloperidol treatment compared with placebo in acutely admitted, adult ICU patients with delirium for the primary and most secondary outcomes. The... read more
Antifungal Stewardship in Critically Ill Patients
Antifungal stewardship (AFS) can improve performance measures and decrease antifungal consumption, with no negative impact on outcomes. β-D-glucan (BDG) are helpful to stop unnecessary treatment in patients with IC,... read more
Regular Old Pneumonia Treatment Just Got Better
In 2020, COVID-19 pneumonia became so common that "old-fashioned" bacterial pneumonia suddenly seemed rare. They look very different on x-ray. See if you can spot the differences. A new study from France tipped the scales... read more
Early Calorie and Protein Restriction Associated with Faster Recovery in Ventilated Patients
Compared with standard calorie and protein targets, early calorie and protein restriction did not decrease mortality but was associated with faster recovery and fewer complications. Of 3,044 patients randomly assigned... read more
ICU Precision Diagnosis with Metagenomic Sequencing
Despite promising results, metagenomics remains underutilized in the ICU. Several factors still limit its inclusion in routine critical care, including the lack of definitive clinical trials testing its utility, few laboratories... read more
Effect of ICU Quality Control Indicators on VAP Incidence Rate and Mortality
This study highlights the association between the ICU quality control (QC) factors and ventilator-associated pneumonia (VAP) incidence rate and mortality. The process factors rather than the structural factors need to be... read more
IHCA Variation Throughout the Day
We observed higher rates of hospital cardiac arrest (IHCA), and poorer outcomes at night. However, in those admitted to ICU, this variation was absent. This suggests patient factors and processes of care issues contribute... read more
Methylene Blue Reduced Length of Stay in ICU
In patients with septic shock, methylene blue (MB) initiated within 24 h reduced time to vasopressor discontinuation and increased vasopressor-free days at 28 days. It also reduced length of stay in ICU and hospital without... read more
Is It Time to Abandon Routine Mask Ventilation Before Intubation?
Mask ventilation in the period between induction and intubation has traditionally been used to confirm the ability to ventilate the patient while awaiting the onset of adequate neuromuscular blockade. However, recent studies... read more
Intensive Care in Nephrology
The field of intensive care in nephrology is a rapidly evolving one, with research starting to translate into clinical guidelines and standards. Encompassing core subjects in critical care and nephrology, as well as specific... read more
