Tight Blood-Glucose Control without Early Parenteral Nutrition in the ICU

In critically ill patients who were not receiving early parenteral nutrition, tight glucose control did not affect the length of time that ICU care was needed or mortality. Of 9,230 patients who underwent randomization,... read more

A Beginner’s Guide to Vasopressors: Inodilators, Inopressors, Methylene Blue, Midodrine: An Essential Manual to Understanding Cardiac Medications and Cardiovascular Hemodynamic Mechanics

The use of pressors and dilators are common in intensive care units, especially concerning the heart. With different mechanisms of action and titrations, it is essential to know how each of the drugs perform and the potential... read more

A Beginner’s Guide to Vasopressors: Inodilators, Inopressors, Methylene Blue, Midodrine: An Essential Manual to Understanding Cardiac Medications and Cardiovascular Hemodynamic Mechanics

Epidemiology of Surgery Associated Acute Kidney Injury (EPIS-AKI)

In a comprehensive multinational study, approximately one in five patients develop PO-AKI after major surgery. Increasing severity of PO-AKI is associated with a progressive increase in adverse outcomes. Our findings indicate... read more

Tracheal Intubation of Critically Ill Adults: Video vs. Direct Laryngoscopy

Successful intubation on the first attempt occurred in 600 out of 705 patients (85.1%) in the video-laryngoscope group and 504 out of 712 (70.8%) in the direct-laryngoscope group (ARR, 14.3%; 95% CI, 9.9 to 18.7; p... read more

Hematologic Challenges in the Critically Ill

This volume provides a comprehensive overview of hematologic issues that clinicians regularly encounter in the critical care environment. The text features hematologic scenarios that affect the adult ICU patient, outlines... read more

Hematologic Challenges in the Critically Ill

Delirium in Critically Ill Patients – Haloperidol Treatment

Haloperidol may reduce mortality and likely result in little to no change in the occurrence of SAEs/SARs compared with placebo in critically ill patients with delirium. However, the results were not statistically significant... read more

Nursing in Critical Care Setting: An Overview from Basic to Sensitive Outcomes

This book provides essential insights into how the approach to nursing care in ICU patients has markedly changed over recent years. It shows how the focus has progressively moved away from the technical approach that characterized... read more

Nursing in Critical Care Setting: An Overview from Basic to Sensitive Outcomes

Ferroptosis and Pyroptosis Signatures in Critical COVID-19 Patients

Critical COVID-19 patients admitted to the intensive care unit (ICU) frequently suffer from severe multiple organ dysfunction with underlying widespread cell death. Ferroptosis and pyroptosis are two detrimental forms... read more

Staphylococcus Epidermidis Infections Linked to ICU Septic Shocks

Bloodstream infections caused by Staphylococcus epidermidis (SE-BSI) may lead to septic shock in patients admitted to intensive care unit (ICU), according to a study. For the study, researchers looked at a retrospective... read more

Hypercalcemia of Immobility in Critically Ill Patients

Significant hypercalcemia can occur in intensive care unit (ICU) patients. Immobilization hypercalcemia has been infrequently reported after ICU admission. Patients, therefore, usually require extensive workup to rule out... read more

Cluster of Carbapenemase-Producing Carbapenem-Resistant Pseudomonas Aeruginosa Among ICU Patients

Treatment of carbapenemase-producing carbapenem-resistant Pseudomonas aeruginosa (CP-CRPA) infections is challenging because of antibiotic resistance. CP-CRPA infections are highly transmissible in health care settings because... read more

Nasotracheal vs. Orotracheal Intubation for Sedation in Critically Ill Patients

Nasotracheal intubation (NTI) may be used for long term ventilation in critically ill patients. Although tracheostomy is often favored, NTI may exhibit potential benefits. Compared to orotracheal intubation (OTI), patients... read more

Effect of Antimicrobial De-escalation Strategy on 14-day Mortality Among ICU Patients

The prevalence of antimicrobial de-escalation (ADE) strategy was low among intensive care unit patients. The ADE strategy demonstrated a protective effect or no adverse effect on 14-day mortality compared to the No Change... read more

Inhaled Epoprostenol Compared With Nitric Oxide for Right Ventricular Support After Major Cardiac Surgery

Right ventricular failure (RVF) is a leading driver of morbidity and mortality after major cardiac surgery for advanced heart failure, including orthotopic heart transplantation and left ventricular assist device implantation.... read more

Outcomes and Characteristics of Cardiac Arrest in Children with Pulmonary Hypertension

In this prospective study of children who received CPR in intensive care units, a pre-existing diagnosis pulmonary hypertension was present in 16% of children but was not associated with statistically significant differences... read more

Optimal Fluid Therapy for Sepsis Management in Critically Ill Adults

For a study, researchers aimed to analyze the fluid treatment in septic critically ill adults. About 20% to 30% of patients were admitted to an ICU with sepsis. In sepsis patients, investigators observed intravenous fluid... read more

Propofol in ICU Settings: Understanding and Managing Anti-Arrhythmic, Pro-Arrhythmic Effects, and Propofol Infusion Syndrome

Propofol has revolutionized anesthesia and intensive care medicine owing to its favorable pharmacokinetic characteristics, fast onset, and short duration of action. This drug has been shown to be remarkably effective in numerous... read more

Severe Hypertriglyceridemia: A 10-Year Review

This study shows the morbidity profile associated with severe hypertriglyceridemia (SHTG), with a high level of ICU admissions and also a high level of the use of plasmapheresis. In our population, this approach had good... read more

Every Deep-Drawn Breath: A Critical Care Doctor on Healing, Recovery, and Transforming Medicine in the ICU

A world-renowned critical care doctor offers hope for ICU patients and their families in this timely, urgent, and compassionate narrative. Over the next ten years, 40 to 60 million people in this country will be admitted... read more

Every Deep-Drawn Breath: A Critical Care Doctor on Healing, Recovery, and Transforming Medicine in the ICU

ICU Delirium – A Decade of Learning

Think of delirium as the phenotypic manifestation of global, acute brain dysfunction that can deprive patients of their dignity. This syndrome of acute changes in awareness, attention, and cognition is an independent... read more

Pulmonary Artery Catheter Use and Mortality in the Cardiac ICU

The appropriate use of pulmonary artery catheters (PACs) in critically ill cardiac patients remains debated. There is wide variation in the use of PACs that is not fully explained by patient level-factors and appears driven... read more

Acute Kidney Injury in ICU Patients

Patients admitted to the intensive care unit are prone to various complications, one of which is acute kidney injury (AKI). The etiology of acute kidney injury can be multifactorial. Among the various causes, sepsis remains... read more