The impact of physical medicine and rehabilitation consultation on clinical outcomes in the SICU

The impact of a physical medicine and rehabilitation (PM&R) consultation on clinical outcomes in critically ill surgical patients remains unclear. The aim of this study is to examine whether the patients who received PM&R... read more

Probiotics for the Prevention of Ventilator-Associated Pneumonia

Presently, there is conflicting evidence regarding the efficacy of probiotics in the prevention of ventilator-associated pneumonia (VAP). This meta-analysis was conducted to update current clinical evidence and evaluate the... read more

Physiological Responses to In-Bed Cycle Ergometry Treatment in ICU Patients with External Ventricular Drainage

These data suggest that supine CE in a heterogeneous cohort of neurocritical care patients with EVDs is safe and tolerable. Larger prospective studies are needed to determine the efficacy and optimal dose and timing of supine... read more

Long-term Outcomes of Hospital Survivors Following an ICU Stay

Australian patients admitted to ICU who survive to discharge have worse long-term survival than the general population, except for the elderly admitted to ICU following cardiac surgery. These findings may assist during goal-of-care... read more

Principles of Critical Care

Quickly and accurately diagnose and treat the critically ill patient with guidance from the field's definitive text. Considered the field's definitive text, Principles of Critical Care offers unmatched coverage of the diagnosis... read more

Principles of Critical Care

Hemodynamic Management Challenges of Septic Shock

Sepsis is one of the main causes of admission to the Intensive Care Unit (ICU). It is defined as a life-threatening organ dysfunction, caused by dysregulated host response to infection (Singer et al. 2016). Septic shock... read more

Vasopressor Choice and Timing in Vasodilatory Shock

Vasodilatory shock is the most common form of circulatory shock encountered in patients admitted to the intensive care unit (ICU). Sepsis is the predominant etiology, but other causes of vasodilatory shock include postoperative... read more

Hemodynamic Monitoring (Lessons from the ICU)

This book, part of the European Society of Intensive Care Medicine textbook series, teaches readers how to use hemodynamic monitoring, an essential skill for today's intensivists. It offers a valuable guide for beginners,... read more

Hemodynamic Monitoring (Lessons from the ICU)

The Family in Preventing Delirium in the ICU

Extended visits, development of family-mediated activities, and redirection are non-pharmacological strategies that reduce the incidence of delirium in the ICU and offer multiple benefits to the patient and family/caregiver. The... read more

Critically Ill Pregnant Women with COVID-19: Management and Outcome

Coronavirus disease 2019 (COVID-19)-infected pregnant women are at higher risk of intensive care unit (ICU) admission and mechanical ventilation. Because reports describing the clinical course and management of critically... read more

Melatonin in ICU Delirium: Shining Light on the Hormone of Darkness

Delirium represents a form of acute brain dysfunction predictive of excess death and long-term cognitive impairment in critically ill patients. For many years, we have wondered whether pharmacological doses of melatonin would... read more

Essentials of Shock Management: A Scenario-Based Approach

This book is designed to offer the reader first-rate guidance on shock management in the real world. Comprehensive, evidence-based, and up-to-date instruction is provided on optimal care of patients with different types of... read more

Essentials of Shock Management: A Scenario-Based Approach

Incidence of Delirium in ICU Inpatients After Cognitive Exercise Intervention

In this study, the relevant RCTs on cognitive exercise in ICU inpatients with delirium were screened for systematic evaluation and meta-analysis, aiming to explore the impact of cognitive exercises and routine nursing on... read more

Interventional Critical Care: A Manual for Advanced Care Practitioners

This book provides a comprehensive, state-of-the art review of the interventional procedures that can be performed in intensive care settings. The book addresses fundamentals of the indications and technical aspects of procedures,... read more

Interventional Critical Care: A Manual for Advanced Care Practitioners

Balanced Crystalloids Probably Reduce Mortality in the Critically-Ill

As remarked by the authors of the recent PLUS trial, a systematic review and meta-analysis of randomized controlled trials comparing balanced resuscitation fluid to 0.9% saline was reported in the New England Journal of Medicine... read more

Ventriculo-Arterial Coupling Analysis Predicts the Hemodynamic Response to Norepinephrine in Hypotensive Postoperative Patients

In patients with arterial hypotension norepinephrine increased end-systolic ventricular elastance and arterial elastance. The effects of norepinephrine on stroke volume depend on baseline ventriculo-arterial coupling. Although... read more

Prophylactic Melatonin for Delirium in Intensive Care (Pro-MEDIC)

Enteral melatonin initiated within 48 h of ICU admission did not reduce the prevalence of delirium compared to placebo. These findings do not support the routine early use of melatonin in the critically ill. A total of... read more

Balanced Fluid Resuscitation for the Critically-Ill: the PLUS study mirrors the BaSICS

Intravenous fluid therapy is one of the most commonly-performed interventions in all of critical care medicine. Numerous trials over the last 20 years have attempted to identify the ideal fluid for those in the intensive... read more

Information Transfer as a Strategy to Improve Safety in ICU

In an Intensive Care Unit (ICU), we attend people with a wide range of pathologies. All the information obtained from monitoring our critical patients, diagnostic and therapeutic techniques, responses to treatments, action... read more

Clinical Profile and Recovery Pattern of Dysphagia in COVID-19 Patients

COVID-19 considerably impacted swallowing function in the current study. Although many patients recovered within an acceptable timeframe, some experienced persistent severe dysphagia and a protracted recovery with dependence... read more

Cognitive Dysfunction, Psychiatric Distress, and Functional Decline After COVID-19

At approximately 4 months after acute illness, cognitive dysfunction, emotional distress, and functional decline were common among a diverse clinical sample of COVID-19 survivors varying in acute illness severity. Patients... read more

Procalcitonin in the ED: The evidence

Is procalcitonin of any value in the emergency department? Considering that procalcitonin testing is not available in any of my hospitals, I have never been all that interested in this question. But Swami requested a procalcitonin... read more