Checklist for Early Recognition and Treatment of Acute Illness and Injury

A quality-improvement intervention with remote simulation training to implement a decision support tool was associated with decreased nonadherence to daily care processes, shorter length of stay, and decreased mortality. The... read more

Sedation, Analgesia, and Paralysis in COVID-19 Patients in the Setting of Drug Shortages

The rapid spread of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has led to a global pandemic. The 2019 coronavirus disease (COVID-19) presents with a spectrum of symptoms ranging from mild to critical... read more

Virtual Reality Tailored to the Needs of Post-ICU Patients

ICU-specific virtual reality appears safe and more immersive than 2D, implicating that ICU-specific virtual reality is feasible for clinical use. One should however be aware of simulator sickness-related symptoms. Future... read more

Randomised controlled trials in pre-hospital trauma

This mapping review has highlighted that evidence from trials in prehospital trauma is sparse and where trials have been completed, the reporting is generally poor and study designs sub-optimal. There is a continued need,... read more

Rapid Sequence Induction: Where Did the Consensus Go?

The conduct of Rapid Sequence Induction (RSI) in current emergency practice is far removed from the original descriptions of the procedure. Despite this, the principles – rapid delivery of a definitive airway and avoiding... read more

Safety of Arterial Catheterization Using the Distal Radial Approach in ICU Management

Distal radial approach (DRA) may be a safe option for insertion of a new A-line in the ICU. The study included 20 patients with a median age of 70 (interquartile range (IQR): 58.5–77) years: 10 patients with traumas,... read more

Low Technology, Mild Controlled Hypothermia for Necrotizing Enterocolitis Treatment

Low technology, mild controlled hypothermia was feasible, not related to adverse effects, and effective treatment for NEC Modified Bell's Stage II/III. It avoided surgery, bowel perforation, and extensive intestinal resection;... read more

Oral Midodrine Feasibility in Early Sepsis

This study proved the feasibility of clinical trial to use oral midodrine in early sepsis. The study was not powered to detect statistically significant differences between the two groups, and therefore, the results from... read more

Association Between Premorbid Beta-Blocker Exposure and Sepsis Outcomes

This study suggests that β-blocker exposure prior to sepsis, especially to noncardioselective β blockers, may be associated with better outcome. The findings suggest prospective evaluation of β-blocker use in the management... read more

Bodily Pain in Survivors of ARDS

Nearly half of acute respiratory distress syndrome (ARDS) survivors reported bodily pain at 6- and 12-month follow-up; one-third reported pain at both time points. Pre-ARDS unemployment, smoking history, and in-ICU opioid... read more

Trend and Pattern of 100 ARDS Patients Teferred for VV ECMO Treatment

Referral to specialized center for venovenous (VV) ECMO treatment should be considered expeditiously in case of refractory ARDS, which is often lethal. Transport of unstable patients, although challenging, is feasible and... read more

Ultrasound Grayscale Analysis in ARDS COVID-19

Recent evidence regarding the novel coronavirus disease 2019 (COVID19) is growing in describing the characteristics of this disease, with main focus on lung morphology. Few data are available regarding the peripheral and... read more

Promoting Evidence-Based Practice in ARDS

There is a dearth of literature addressing interventions to improve implementation of evidence-based practices in acute respiratory distress syndrome (ARDS). Existing interventions to improve clinician knowledge and facilitate... read more

Prone Positioning in Spontaneously Breathing Subjects With Moderate or Severe ARDS During Invasive Ventilation

In a retrospective analysis of consecutive intubated subjects with moderate or severe ARDS, related or not to COVID-19, spontaneous breathing during prone positioning (PP) was well tolerated and achieved significant improvement... read more

Effect of Neuromuscular Electrical Stimulation on the Recovery of COVID-19 Patients

The rehabilitation of patients with COVID-19 after prolonged treatment in the intensive care unit is often complex and challenging. Patients may develop a myriad of long-term multiorgan impairments, affecting the respiratory,... read more

Critical Care Emergency Medicine

The groundbreaking text on critical care emergency medicine – updated with the latest evidence and recommendations. Critical Care Emergency Medicine has become the standard reference for all clinicians who wish to understand... read more

Critical Care Emergency Medicine

Association Between Pre-Existing Respiratory Disease and COVID-19

Previous studies suggested that the prevalence of chronic respiratory disease in patients hospitalised with COVID-19 was lower than its prevalence in the general population. The aim of this study was to assess whether... read more

Addressing Hospital-Acquired Hypoglycemia

Findings suggest that ensuring a consistent 30-minute window between POC BG measurement and meal delivery enabled nursing staff to perform timely POC BG measurements and administer a more optimal mealtime insulin dose. Increasing... read more

Cardiac Markers Implication in Risk-stratification and Management for COVID-19 Patients

COVID-19 patients with pre-existing coronary artery disease represented a higher abnormal percentage of cardiac markers, accompanied by high mortality and ICU admission rate. BNP together with hs-TNI, α- HBDH, CK-MB and... read more

Bedside Voluntary and Evoked Forces Evaluation in ICU Patients

Around one third of intensive care unit (ICU) patients will develop severe neuromuscular alterations, known as intensive care unit-acquired weakness (ICUAW), during their stay. The diagnosis of ICUAW is difficult and often... read more

Escalation and Withdrawal of Treatment for Patients on ECMO

Discussion between clinicians and families about prognosis and goals was frequent but did not occasion decision-making moments. This study helps explain why communication interventions intended to maintain patient autonomy... read more

Host Endothelial, Epithelial and Inflammatory Response in ICU COVID-19 Patients

These studies demonstrate that, unlike other well-studied causes of critical illness, endothelial dysfunction may not be characteristic of severe COVID-19 early after ICU admission. Pathways resulting in elaboration of acute... read more