Breadth of Antibiotics Trumps Dose and Duration in Driving ICU Superbugs

In a large prospective cohort study across four ICUs (422 patients enrolled from March 2024 to January 2025), 35.8% of patients acquired carbapenem-resistant Gram-negative bacteria (CR-GNB) during their stay. Using sophisticated... read more

Superbugs Are Winning – Time to Fight Back with the Four-Pillar Plan

The relentless global surge in multidrug-resistant (MDR) infections, vividly illustrated by high rates of carbapenem-resistant Acinetobacter in Western Romania and echoed worldwide, is outpacing outdated diagnostic and treatment... read more

Norepinephrine Usage Tips in Perioperative Medicine

Tip 1. Looking beyond vasodilatation: use norepinephrine as first-line vasopressor but reassess the cause of hypotension before escalation. Tip 2. Set a goal of mean arterial blood pressure above 60 mmHg, and individualize... read more

Predicting Sepsis Mortality: The Power of NLR and PCT Clearance

A retrospective cohort study analyzed the dynamic changes of several inflammatory biomarkers to predict mortality in 64 Intensive Care Unit (ICU) patients diagnosed with sepsis. The study, which collected clinical and... read more

Less Sedation, Shorter Stays: The Benefit of Analgesia-Based Protocols

A retrospective study conducted in a 24-bed medical Intensive Care Unit (ICU) compared patient outcomes before and after implementing a new analgesia-based sedation protocol. The research included 79 patients managed... read more

RealMIP: The AI That Sees Death Coming in Real Time

A groundbreaking new framework called RealMIP finally cracks the long-standing problem of real-time mortality prediction in chaotic ICU data streams riddled with missing values and irregular sampling. By combining cutting-edge... read more

Why the 7-Day IV Change Policy Could Cost Lives and Millions

A new economic evaluation of the landmark RSVP trial reveals that adopting 7-day routine IV replacement (deemed “non-inferior” to every-3-day changes based on acute catheter infection rates) may actually be harmful and... read more

Filling the Gap: Non-Drug Interventions After Critical Care

A comprehensive scoping review sought to summarize the current landscape of non-pharmacological interventions aimed at improving patient outcomes following discharge from critical care. From over 41,000 reports screened,... read more

The Pharmacist’s Expanded Role in Critical Care Medicine: A Comprehensive Guide for Practitioners and Trainees

This new book will serve as a useful resource for all pharmacists involved in the management of critically ill patients, whatever their level of experience and training. There are few textbooks aimed specifically at critical... read more

The Pharmacist’s Expanded Role in Critical Care Medicine: A Comprehensive Guide for Practitioners and Trainees

Move Early, Recover Faster: Early Mobilization Slashes ICU Stays Without Adding Risk

An updated systematic review and meta-analysis of 16 high-quality randomized trials (2,385 ICU patients) delivers a clear verdict: starting mobilization within 72 hours of admission is not only safe but powerfully effective.... read more

Steroids Save Lives in Severe Pneumonia and ARDS – Without Spiking Superbug Risk

A rigorous new systematic review and meta-analysis of 20 high-quality trials (3,459 patients) confirms that low-dose, short-course systemic corticosteroids significantly reduce short-term mortality in both severe pneumonia... read more

Master the CCRN Exam Without Guesswork: The Proven Study System with 1200+ Questions, 7 Full-Length Tests & Step-by-Step Strategies to Build ICU Confidence, Save Study Time, and Feel Fully Prepared

What If You Could Stop Second-Guessing and Start Walking into the CCRN Exam Fully Prepared and Confident? Are you overwhelmed by the amount of content to memorize—and unsure where to even begin? Does your mind go blank... read more

Master the CCRN Exam Without Guesswork: The Proven Study System with 1200+ Questions, 7 Full-Length Tests & Step-by-Step Strategies to Build ICU Confidence, Save Study Time, and Feel Fully Prepared

Optimizing Sedation & Analgesia in the ICU, An Issue of Critical Care Clinics, E-Book (The Clinics: Internal Medicine)

In this issue of Critical Care Clinics, guest editors Drs. Yahya Shehabi, Joanna L. Stollings, and Timothy D. Gerard bring their considerable expertise to the topic of Optimizing Sedation and Analgesia in the ICU. Top... read more

Optimizing Sedation & Analgesia in the ICU, An Issue of Critical Care Clinics, E-Book (The Clinics: Internal Medicine)

Mastering ICU Care: Algorithms and Clinical Decision-Making for Residents

This book covers all aspects of ICU care, from diagnostics and treatment modalities to patient management. It features real-world case studies and provides step-by-step guidance on critical care. Additionally, it discusses... read more

Mastering ICU Care: Algorithms and Clinical Decision-Making for Residents

ICU Protocols: A Step-wise Approach, Vol II

The second edition of this highly successful book includes up-to-date notes on the step-wise management of clinical emergencies encountered in everyday intensive care units (ICU). Each thoroughly revised chapter provides... read more

ICU Protocols: A Step-wise Approach, Vol II

ICU Protocols: A Step-wise Approach, Vol I

The second edition of this highly successful book includes up-to-date notes on the step-wise management of clinical emergencies encountered in everyday intensive care units (ICU). Each thoroughly revised chapter provides... read more

ICU Protocols: A Step-wise Approach, Vol I

Echocardiography and Ultrasonography in the ICU: A Comprehensive Text (Respiratory Medicine)

This is a comprehensive textbook on the emerging field of critical care ultrasound and echocardiography. These imaging modalities are being used increasingly in the ICU, and this book contains more detail than any other book... read more

Echocardiography and Ultrasonography in the ICU: A Comprehensive Text (Respiratory Medicine)

Critical Care Pearls: ICU Q&A Handbook for Critical Care Medicine: A Board Review and Daily Clinical Practice. Rapid Reference for Physicians, Fellows & Nurses

In the fast-paced world of intensive care medicine, every second counts and every question matters. Critical Care Pearls – Third Edition delivers over a thousand carefully curated ICU questions and evidence-based answers... read more

Critical Care Pearls: ICU Q&A Handbook for Critical Care Medicine: A Board Review and Daily Clinical Practice. Rapid Reference for Physicians, Fellows & Nurses

Critical Care Nursing Mnemonics: A Fast Recall Guide for ICU and Emergency Nurses

In the world of critical care and emergency nursing, seconds matter—and knowledge must be ready on demand. Critical Care Nursing Mnemonics is your compact, clinical companion designed to help ICU and ER nurses recall essential... read more

Critical Care Nursing Mnemonics: A Fast Recall Guide for ICU and Emergency Nurses

Nutrition in ICU Patients

This book discusses practical topics in critical care nutrition including basic principles and practices in nutrition support in the ICU. Tailoring nutrition solutions is crucial for the development and prognosis of critical... read more

Nutrition in ICU Patients

Critical Care & ICU Made Simple: The Illustrated Bedside Manual for Fast Decision-Making and Real-World Patient Management

Are you overwhelmed by complex ICU textbooks that make critical care harder, not easier? Do you wish you had a practical critical care handbook that helps you make the right call in seconds, not hours? You’ve just found... read more

Critical Care & ICU Made Simple: The Illustrated Bedside Manual for Fast Decision-Making and Real-World Patient Management

AI Spots Deadly Sepsis Clotting Crisis Hours Earlier – Now Live as a Free Web Tool

In a large multi-center retrospective study using the MIMIC-IV and eICU-CRD databases, researchers developed an interpretable machine learning model to predict sepsis-induced coagulopathy (SIC) within 7 days of ICU admission.... read more