Nurses’ knowledge and practices of physical restraints in ICU

The mean scores of nurses' knowledge and practices were 61.5 (SD = 12.1) and 57.4 (SD = 9.7), respectively. More than half of nurses had poor knowledge of PR use and incorrect practice of implementing PR (51.5% and 60.5%,... read more

Clinical characteristics of critically ill patients with COVID-19

In this study of critical patients infected by SARS-CoV-2 in a high-complexity hospital, the majority were comorbid elderly men, a large percentage required invasive mechanical ventilation, and ICU mortality was 25%. Design... read more

ECG Pointers: Cocaine and ST Elevation

This ECG comes from a 21-year-old male with a history of cocaine abuse.  When I say ‘history’, I mean that he just snorted some cocaine and now he has chest pain.  He looks uncomfortable and sweaty, and keeps... read more

Risk factors and events in the adult ICU associated with pain as self-reported at the end of the intensive care unit stay

The short-term and long-term consequences of the most frequent painful procedures performed in the ICU are unclear. This study aimed to identify the risk factors associated with pain-related discomfort perceived by critically... read more

Will the asthma revolution fostered by biologics also benefit adult ICU patients?

Asthma exacerbations are inflammatory events that rarely result in full hospitalization following an ER visit. Unfortunately, certain patients require prolonged support, including occasional external lung support through... read more

Caring for the Sickest COVID-19 Patients: An ICU Story

In an article for the latest issue of Stanford Medicine magazine, I provide a glimpse into the journey Free and his front-line Stanford Health Care colleagues took -- from Day 1 through the following weeks and months -- to... read more

Fishman’s Pulmonary Diseases and Disorders

Since 1980, Fishman's Pulmonary Diseases and Disorders has delivered unparalleled coverage of pulmonary medicine and the underlying basic and applied science upon which clinical practice is based. The Fifth Edition, with... read more

Fishman’s Pulmonary Diseases and Disorders

Surgery guidance updated for hospitals struggling with capacity constraints

Four healthcare groups again updated their guidance for hospitals to maintain essential surgeries during the COVID-19 pandemic. The American Hospital Association, American College of Surgeons, American Society of Anesthesiologists... read more

Epidemiology of Invasive Pulmonary Aspergillosis Among COVID-19 Intubated Patients

We found a high incidence of CAPA among critically ill COVID-19 patients and that its occurrence seems to change the natural history of disease. A total of 108 patients were enrolled. Prospective, multicentre study... read more

Increased Dead Space Ventilation and Refractory Hypercapnia in Patients with COVID-19

We speculate that thromboinflammation with pulmonary microvasculature occlusion leads to a sudden increase in dead space and shunt resulting in severe hypercapnia and hypoxemia in coronavirus disease 2019 patients. Early... read more

The Use of Venous Doppler to Predict Adverse Kidney Events in a General ICU Cohort

This study indicates that portal and hepatic flows may be clinical useful tools to help identify patients at risk for renal injury. It is likely that they are indicative of elevated right atrial pressure causing venous congestion,... read more

Critical Care Beds Are No Use Without Enough Specialist Staff

In 2020 there have been announcements of the expansion of critical care capacity across the NHS, while at the same time headlines have detailed stories of hospitals running out of critical care beds. And this week dire warnings... read more

Practical Guidance for Evidence-Based ICU Family Conferences

Because most critically ill patients lack decision-making capacity, physicians often ask family members to act as surrogates for the patient in discussions about the goals of care. Therefore, clinician-family communication... read more

Balancing Intervention and Inaction During the COVID-19 Pandemic

More than 38 million people worldwide have been infected with the severe acute respiratory syndrome (SARS) coronavirus 2, creating intense pressure on clinicians to offer state-of-the-art, life-saving treatment to patients. The... read more

Factors Associated to ICU Mortality in Critically Ill Patients Infected with COVID-19 in Spain

Older COVID-19 patients with higher APACHE II scores on admission, those who developed AKI grades II or III and/or septic shock during ICU stay had an increased risk-of-death. ICU mortality was 31%. A total of 663 patients... read more

Critical Care Medicine: Principles of Diagnosis and Management in the Adult

Now completely revised to bring you up to date with the latest advances in the field, Critical Care Medicine: Principles of Diagnosis and Management in the Adult, 5th Edition, delivers expert, practical guidance on virtually... read more

Critical Care Medicine: Principles of Diagnosis and Management in the Adult

Clinical Communication with Families in the Age of COVID-19

The admission of a critically ill patient to an intensive care unit (ICU) is a distressing event for the patient, their family and friends, which has been amplified by the impact of the covid-19 pandemic. Many hospitals... read more

Effect of Early Activity Combined with Early Nutrition on Acquired Weakness in ICU Patients

This trial has the potential to identify a novel strategy for preventing or managing ICU-AW. The findings may increase the clinical knowledge about nutrition and mobilization interventions for people with ICU-AW, and contribute... read more

Stress Hyperglycemia and Mortality in Subjects With Diabetes and Sepsis

Stress-induced hyperglycemia is a relevant prognostic factor also in the presence of diabetes. Mild-to-moderate stress hyperglycemia is considered a protective reaction to providing fuel for the immune system and brain at... read more

Gastrointestinal Complications in Critically Ill Patients With and Without COVID-19

This study found a higher rate of gastrointestinal complications, including mesenteric ischemia, in critically ill patients with COVID-19 compared with propensity score–matched patients without COVID-19, suggesting a distinct... read more

Fibrin-derived Peptide as Salvage Treatment in Critically Ill Patients with COVID-19-associated ARDS

After SARS-CoV-2 first occurred in China in December of 2019, it set out to become a global pandemic. Critically ill patients constitute about 2–9% of all infected patients and progress from pneumonia and hypoxemia to multi-organ... read more

Advances In ICU Care Are Saving More Patients Who Have COVID-19

One thing that has improved a lot over the course of the pandemic is treatment of seriously ill COVID-19 patients in intensive care units. Here's one man's success story. If you think all the coronavirus news is bad, consider... read more