Marburg Virus Disease Outbreaks in Equatorial Guinea and Tanzania

The Centers for Disease Control and Prevention (CDC) is issuing this Health Alert Network (HAN) Health Advisory to inform clinicians and public health departments in the United States about two confirmed outbreaks of Marburg... read more

Marburg Virus Disease Outbreaks in Equatorial Guinea and Tanzania

Antifungal Stewardship in Critically Ill Patients

Antifungal stewardship (AFS) can improve performance measures and decrease antifungal consumption, with no negative impact on outcomes. β-D-glucan (BDG) are helpful to stop unnecessary treatment in patients with IC,... read more

Antifungal Stewardship in Critically Ill Patients

Regular Old Pneumonia Treatment Just Got Better

In 2020, COVID-19 pneumonia became so common that "old-fashioned" bacterial pneumonia suddenly seemed rare. They look very different on x-ray. See if you can spot the differences. A new study from France tipped the scales... read more

Regular Old Pneumonia Treatment Just Got Better

Optimal Bundle of Recommendations for Sepsis

The aim of this retrospective cohort study was to identify among the Surviving Sepsis Campaign (SSC) guidelines the optimal bundle of recommendations that minimize 28-day mortality. The bundle of six recommendations is... read more

Optimal Bundle of Recommendations for Sepsis

PLASMIC Score Role in the Management of Thrombotic Thrombocytopenic Purpura

At centers that are resource-limited and where ADAMTS-13 testing is not readily available, it is imminent that treatment is started immediately based on the clinical presentation and PLASMIC score. A PLASMIC score can... read more

PLASMIC Score Role in the Management of Thrombotic Thrombocytopenic Purpura

Advances in Microbiology, Infectious Diseases and Public Health: Volume 15

This book series focuses on current progress in the broad field of medical microbiology, and covers both basic and applied topics related to the study of microbes, their interactions with human and animals, and emerging issues... read more

Advances in Microbiology, Infectious Diseases and Public Health: Volume 15

Hospital Acquired Infections, Multidrug Resistant (MDR) Bacteria, Alternative Approaches to Antibiotic Therapy

Bacterial resistance to known and currently used antibiotics represents a growing issue worldwide. It poses a major problem in the treatment of infectious diseases in general and hospital-acquired infections in particular.... read more

Hospital Acquired Infections, Multidrug Resistant (MDR) Bacteria, Alternative Approaches to Antibiotic Therapy

COVID-19 Treatment Guidelines New Version Published

The COVID-19 Treatment Guidelines Panel (the Panel) is pleased to announce the publication of an updated version of the Coronavirus Disease 2019 (COVID-19) Treatment Guidelines. In the United States, the prevalence of... read more

COVID-19 Treatment Guidelines New Version Published

Early Identification of Intra-abdominal Infection and Sepsis

This case report illustrates the ability of the novel biomarker pancreatic stone protein (PSP) concentrations to act as a warning sign, allowing the early identification of intra-abdominal infection and post-operative peritonitis... read more

Early Identification of Intra-abdominal Infection and Sepsis

China: Nearly 250 million people might be infected with COVID-19

According to a leaked government document that has been circulating on social media, it is estimated that up to 248 million people in China may have been infected with COVID-19 since control measures were lifted. This... read more

China: Nearly 250 million people might be infected with COVID-19

Clarifying the Fictions Surrounding Sepsis: Strategies for Improved Management and Outcomes

It is important to clarify the myths surrounding sepsis and to provide a clear understanding of the condition. This can help set realistic expectations about outcomes and inform effective strategies for managing sepsis, including... read more

Clarifying the Fictions Surrounding Sepsis: Strategies for Improved Management and Outcomes

Algorithm that Detects Sepsis Cut Deaths by 18%

Hospital patients are at risk of a number of life-threatening complications, especially sepsis—a condition that can kill within hours and contributes to one out of three in-hospital deaths in the U.S. Overworked doctors... read more

Algorithm that Detects Sepsis Cut Deaths by 18%

Septic Shock Developing Later During Hospital Stay Associated with Higher Mortality

In-hospital mortality continued to rise as admission-shock-onset-time increased in patients with septic shock. No clear dichotomization between early and late septic shock could be ascertained, and this categorization may... read more

Septic Shock Developing Later During Hospital Stay Associated with Higher Mortality

Care Step Pathway an Effective Tool For Clinicians Caring for Mechanical Ventilated COVID-19 Patients

The Care Step Pathway (CSP) described in this article was developed to increase awareness of the potential association of SARS-CoV-2 infection with invasive fungal infections, particularly pulmonary aspergillosis. The... read more

Care Step Pathway an Effective Tool For Clinicians Caring for Mechanical Ventilated COVID-19 Patients

Co-infection and ICU-acquired Infection in COVID-19 ICU Patients

In patients with severe COVID-19 in the first wave, co-infection at admission to ICU was relatively rare but antibiotic use was in substantial excess to that indication. ICU-AI were common and were significantly associated... read more

Co-infection and ICU-acquired Infection in COVID-19 ICU Patients

Trauma, Eighth Edition

Hailed by readers and reviewers for its expert authorship and high-yield clinical content, Trauma is unquestionably the field's definitive text. Enhanced by a full-color design and a high-quality atlas of anatomic drawings... read more

Trauma, Eighth Edition

Postoperative Sepsis Infection Can Be Identified Using Gene Expression Signatures

Host biomarker signatures may be able to identify postoperative infection or sepsis up to three days in advance of clinical recognition. If validated in future studies, these signatures offer potential diagnostic utility... read more

Postoperative Sepsis Infection Can Be Identified Using Gene Expression Signatures