Risks and Burdens of Incident Diabetes in Long COVID

Risks and Burdens of Incident Diabetes in Long COVID

In the post-acute phase, we report increased risks and 12-month burdens of incident diabetes and antihyperglycaemic use in people with COVID-19 compared with a contemporary control group of people who were enrolled during... read more

ICM White Paper Proposes Infection Prevention Roadmap Integrating AMR and Sepsis

ICM White Paper Proposes Infection Prevention Roadmap Integrating AMR and Sepsis

The COVID-19 pandemic has put a spotlight on the devastating global health and societal implications an infection can have when there are no preventative interventions or treatment options available. Many countries and most... read more

Comparative analysis of the risks of hospitalisation and death associated with COVID-19 variants in England

Comparative analysis of the risks of hospitalisation and death associated with COVID-19 variants in England

The risk of severe outcomes following SARS-CoV-2 infection is substantially lower for omicron than for delta, with higher reductions for more severe endpoints and significant variation with age. Underlying the observed risks... read more

Electronic Pneumonia Decision Support Helps Reduce Mortality by 38% in Community Hospitals

Electronic Pneumonia Decision Support Helps Reduce Mortality by 38% in Community Hospitals

Pneumonia was the leading cause of death from infectious diseases in the United States, even before the COVID-19 pandemic, and continues to be a leading cause of death. In the study, researchers at Intermountain Healthcare... read more

Critically Ill Pregnant Women with COVID-19: Management and Outcome

Critically Ill Pregnant Women with COVID-19: Management and Outcome

Coronavirus disease 2019 (COVID-19)-infected pregnant women are at higher risk of intensive care unit (ICU) admission and mechanical ventilation. Because reports describing the clinical course and management of critically... read more

Clinical, Biological and Molecular Aspects of COVID-19

Clinical, Biological and Molecular Aspects of COVID-19

The novel coronavirus 2019 (COVID-19) has caused a serious global pandemic in just eight months. Nearly every country and territory in the world has been affected by the virus. The virulence and infection rate of the... read more

Indicators for Monitoring COVID-19 Community Levels and Making Public Health Recommendations

Indicators for Monitoring COVID-19 Community Levels and Making Public Health Recommendations

Widespread uptake of COVID-19 vaccines that are highly effective against severe illness and death, the accrual of high rates of vaccine- and infection-induced immunity at the population level, and the availability of effective... read more

Lung Ultrasonography Beyond the Diagnosis of Pediatrics Pneumonia

Lung Ultrasonography Beyond the Diagnosis of Pediatrics Pneumonia

Pneumonia is a prevalent disease with considerable morbidity and mortality among the pediatric population. Early diagnosis and swift commencement of the correct treatment are vital for a favorable clinical outcome. Along... read more

Anticoagulation in COVID-19 Patients

Anticoagulation in COVID-19 Patients

Clinical, laboratory, and autopsy findings support an association between COVID-19 and thromboembolic disease. Acute COVID-19 infection is characterized by mononuclear cell reactivity and pan-endothelialitis, contributing... read more

Infection Microbiology and Management

Infection Microbiology and Management

Infection: Microbiology and Management provides a core resource for the understanding of medical microbiology and infectious diseases. Content covers microbiological and clinical diagnosis, through to clinical management,... read more

Ascending Aortic Thrombus After COVID-19 Infection

Ascending Aortic Thrombus After COVID-19 Infection

SARS-CoV-2 predisposes patients to both venous and arterial thromboembolism, including ascending aortic thrombus. The current guidelines for anticoagulation recommend three to six months of continuous anticoagulation... read more

Cancer Treatments Not Associated with Inferior COVID-19 Outcomes

Cancer Treatments Not Associated with Inferior COVID-19 Outcomes

The findings of this study of patients with active cancer suggest that recent systemic anticancer treatments (SACTs) is not associated with inferior outcomes from COVID-19 infection. This has relevance for the care of... read more

Antiviral Drug Discovery and Development

Antiviral Drug Discovery and Development

This book summarizes state-of-the-art antiviral drug design and discovery approaches starting from natural products to de novo design, and provides a timely update on recently approved antiviral drugs and compounds in advanced... read more

Procalcitonin in the ED: The evidence

Procalcitonin in the ED: The evidence

Is procalcitonin of any value in the emergency department? Considering that procalcitonin testing is not available in any of my hospitals, I have never been all that interested in this question. But Swami requested a procalcitonin... read more

Adult Sepsis Hospitalization and Risk of Subsequent Cardiovascular Events

Adult Sepsis Hospitalization and Risk of Subsequent Cardiovascular Events

Adult sepsis survivors experience an increased hazard of major cardiovascular events compared to survivors of a non-sepsis hospitalization. 254,241 adult sepsis survivors were matched to adult survivors of non-sepsis hospitalization... read more

Percutaneous vs. Surgical Cannulation for Femoro-Femoral VA-ECMO in Cardiogenic Shock Patients

Percutaneous vs. Surgical Cannulation for Femoro-Femoral VA-ECMO in Cardiogenic Shock Patients

Compared with surgical cannulation, percutaneous cannulation was independently associated with lower in-hospital mortality and fewer complications. Among 12,592 patients meeting study inclusion, 9,249 (73%) underwent percutaneous... read more

Defining COVID-19 Associated Pulmonary Aspergillosis

Defining COVID-19 Associated Pulmonary Aspergillosis

The reported prevalence of CAPA in ICU patients with COVID-19 varies greatly by study and may be related to surveillance protocols and inconsistent definitions which may inflate the prevalence of this complication. Further... read more