Tag: ischemia
Workbook on Hemodynamic Management
This workbook focuses on hemodynamics management. Hemodynamic management should be aimed at minimizing the ischemic injury. Cerebral ischemia impairs the brain's ability to autoregulate its circulation through vasoconstriction... read more
Atrial Fibrillation Status and Associations with Adverse Clinical Outcomes in COVID-19 Patients
COVID-19 patients with atrial fibrillation (AF) are at high risk of adverse clinical outcomes. Such patients may need increased surveillance and consideration for early anticoagulation. Patients admitted with COVID-19... read more
Lactated Ringer’s a Clear Winner for Pancreatitis Resuscitation
Pancreatitis, a common and challenging condition, presents frequently in emergency departments across the country, affecting around 34 of every 100,000 adults annually. This often-severe disease is marked by inflammation... read more
A Perspective on Post-Cardiac Arrest Syndrome
This book presents a valuable new perspective on Post-Cardiac Arrest Syndrome (PCAS), which was defined as system failure following whole-body ischemia-reperfusion injuries by the 2008 International Liaison Committee on Resuscitation.... read more
Feeding Challenges in the ICU
For critically ill patients, timely nutritional support can aid recovery and reduce mortality risk. But what about a patient in septic shock who is receiving vasopressor therapy, or one who requires prone positioning or extracorporeal... read more
Troponin Role in the Diagnosis and Treatment of Acute Pulmonary Embolism
Acute pulmonary embolism (APE) is a cardiovascular disease with severe consequences, wherein cardiac troponin (Tn) plays a pivotal role in diagnosis and treatment. This article reviews the various roles of Tn in managing... read more
EKG/ECG Interpretation Made Easy
In this guide, you will understand how ECGs are performed, what they represent about the heart, and what it means to see something you don't think is normal. Before you get into the hard stuff—the actual interpretation... read more
Revisiting VA-ECMO in Infarct-related Cardiogenic Shock
Despite advances in medical therapies and coronary revascularization, infarct-related cardiogenic shock remains a life-threatening emergency with high death rates. Temporary mechanical circulatory support, including peripheral... read more
A Case of Chronic Mesenteric Ischemia Due to Celiac and Mesenteric Artery Thrombosis
Chronic mesenteric ischemia (CMI) is uncommon and accounts for approximately 5% of cases. CMI presents with non-specific symptoms, making it difficult to diagnose, and requires complex management involving interprofessional... read more
The Vasopressin Loading for Refractory Septic Shock Study
Vasopressin loading may be safely introduced for septic shock. Vasopressin loading may be used to predict responses to its continuous infusion and select appropriate strategies to increase blood pressure. 92 patients were... read more
Hemodialysis as an Effective Treatment for Combined Amlodipine and Metformin Overdose
Introducing emergency dialysis will lead to significant outcomes in mortality and morbidity in patients with combined toxicity of amlodipine and metformin. Moreover, non-ST elevation myocardial infarction is also expected... read more
Atrial Fibrillation and Ischemic Stroke Patients While on Oral Anticoagulation
Patients with Atrial Fibrillation (AF) and ischemic stroke while on oral anticoagulation are at increased risk of recurrent ischemic stroke and death. These patients currently have an unmet medical need. Individual participant... read more
Acute Ischemic Stroke: Recent Advances in Reperfusion Treatment
Stroke is a major clinical challenge. The authors note that during the last 5–7 years, tremendous progress was achieved in the reperfusion treatment of acute ischemic stroke during its first few hours from symptom onset.... read more
Use of Cardiac POCUS in Diagnosis of HFrEF in a Patient with Ischemic Stroke
Ischemic strokes in younger adults, those 18 to 50 years old, account for approximately 10% to 15% of all ischemic strokes. Risk factors for stroke between younger and older patients tend to be similar. Younger patients... read more
Intravenous Tenecteplase vs. Alteplase for Acute Ischemic Stroke
Between Dec 10, 2019, and Jan 25, 2022, 1,600 patients were enrolled and randomly assigned to tenecteplase (n=816) or alteplase (n=784), of whom 1577 were included in the intention-to-treat (ITT) population (n=806 tenecteplase;... read more
Hemodynamic Status During Endovascular Stroke Treatment
In our protocol-based setting, intraprocedural pre-recanalization BP reductions during endovascular therapy were not associated with functional outcome. However, higher intraprocedural pre-recanalization SBP and MAP were... read more
Percutaneous vs. Surgical Cannulation for Femoro-Femoral VA-ECMO in Cardiogenic Shock Patients
Compared with surgical cannulation, percutaneous cannulation was independently associated with lower in-hospital mortality and fewer complications. Among 12,592 patients meeting study inclusion, 9,249 (73%) underwent percutaneous... read more
Troponin Elevation in Non-cardiac Critical Illness
This article is about how to approach ischemia evaluation for the "non-cardiac" critically ill patient (someone admitted for a problem such as sepsis, stroke, or DKA). This is tough. We want to be thorough enough not to miss... read more
Systematic Approach to the Peripheral Vascular Exam: Pearls & Pitfalls
A 62-year-old male with a history of hypertension, congestive heart failure, type II diabetes mellitus, and tobacco use presents to the emergency department (ED) with severe left lower leg pain that started six hours ago.... read more
Lipid Mediators in Critically Ill Patients: A Step Towards Precision Medicine
In this review, we provide an overview of the role of fatty acid-derived lipid mediators as endogenous regulators of the inflammatory, anti-inflammatory and pro-resolving response and future directions for use of clinical... read more
Impact of implantation time on early function of cardiac transplant
Data on out-of-ice implantation ischemia in heart transplant are scarce. We examined implantation time's impact on allograft dysfunction.METHODS: We conducted a single-site retrospective review of all primary adult heart... read more
