Should We Prolong the Observation Period for Neurological Recovery After Cardiac Arrest?

Up to 9.6% of cardiac arrest patients with favorable outcomes recover consciousness after the recommended 7 days of observation, indicating the observation time of 7 days seems justified but longer duration may be needed.... read more

Diaphragm Ultrasonography in ICU: Why, How, and When To Use It?

An overview of the principles and current applications of diaphragm ultrasound and innovative ultrasound-based techniques. In the ICU, ultrasound is starting to be acknowledged as a useful tool for studying the diaphragm.... read more

ICP Monitoring in Patients with Acute Brain Injury

The use of intracranial pressure (ICP) monitoring and ICP management varies greatly across centres and countries. The use of ICP monitoring might be associated with a more intensive therapeutic approach and with lower 6-month... read more

Standardized post-resuscitation damage assessment of two mechanical chest compression devices

The LUCAS 2 device shows superior resuscitation outcomes and less thoracic injuries compared to Corpuls cpr when used for experimental CPR in juvenile pigs. Researchers should be aware that different mCCDs for experimental... read more

Health Systems Successfully Leverage Tele-ICU During Pandemic and Intend to Continue

Help during the pandemic for overwhelmed, overworked intensive care unit (ICU) nurses at some health systems came in the form of experienced tele-ICU nurses working remotely to support on-site colleagues as they cared for... read more

Clinical strategies for implementing lung and diaphragm-protective ventilation

Mechanical ventilation may have adverse effects on both the lung and the diaphragm. Injury to the lung is mediated by excessive mechanical stress and strain, whereas the diaphragm develops atrophy as a consequence of low... read more

Virtual Reality Tailored to the Needs of Post-ICU Patients

ICU-specific virtual reality appears safe and more immersive than 2D, implicating that ICU-specific virtual reality is feasible for clinical use. One should however be aware of simulator sickness-related symptoms. Future... read more

A Practical Integrated Radiomics Model Predicting COVID-19 Hospitalization

It has been widely demonstrated that radiological imaging significantly contributes to diagnosing and monitoring pulmonary and systemic involvement of patients affected by COVID-19 using different techniques like chest X-ray... read more

A novel, hands-free ultrasound patch for continuous monitoring of quantitative Doppler in the carotid artery

Quantitative Doppler ultrasound of the carotid artery has been proposed as an instantaneous surrogate for monitoring rapid changes in left ventricular output. Tracking immediate changes in the arterial Doppler spectrogram... read more

Technical Aspects and Clinical Applications in Lung Ultrasound

Lung ultrasound is increasingly used in emergency departments, medical wards, and critical care units—adult, pediatric, and neonatal. In vitro and in vivo studies show that the number and type of artifacts visualized change... read more

Outcomes and Risk Factors Associated with COVID-19 Infection of Patients with Multiple Sclerosis

In this registry-based cross-sectional study, increased disability was independently associated with worse clinical severity including death from COVID-19. Other risk factors for worse outcomes included older age, Black race,... read more

Cardiorespiratory Compromise in the Perioperative Environment

Perioperative cardiorespiratory compromise is common and goes largely undetected. Predictive cardiorespiratory indices can help in early detection of harmful deviations and guide preemptive treatment. Using continuous... read more

Resumption of Cardiac Activity after Withdrawal of Life-Sustaining Measures

After withdrawal of life-sustaining measures, transient resumption of at least one cycle of cardiac activity after pulselessness occurred in 14% of patients according to retrospective analysis of waveforms; only 1% of such... read more

Association of Convalescent Plasma Treatment With Clinical Outcomes in Patients With COVID-19

Treatment with convalescent plasma compared with placebo or standard of care was not significantly associated with a decrease in all-cause mortality or with any benefit for other clinical outcomes. The certainty of the evidence... read more

COVID-19 and VILI: Mechanical Power Measurement

The COVID-19 pandemic has increased the need for a bedside tool for lung mechanics assessment and ventilator-induced lung injury (VILI) monitoring. Mechanical power is a unifying concept including all the components which... read more

The Risk of False Negative Results with the Curative COVID-19 Test

The U.S. Food and Drug Administration (FDA) is alerting patients and health care providers of the risk of false results, particularly false negative results, with the Curative SARS-Cov-2 test. Risks to a patient of a... read more

Estimate Death Probabilities of Hospitalized Patients with COVID-19

The Covid-19 pandemic has become a global public health crisis and providing optimal patient care while preventing a collapse of the healthcare system is a principal objective worldwide. Here we describe a formula, requiring... read more

Mechanical Ventilators for Non-invasive Ventilation

This book analyzes and describes the whole spectrum of technical elements related with non-invasive mechanical ventilators technologies, ventilator modes and complementary technologies for correct interpretation and clinical... read more

Mechanical Ventilators for Non-invasive Ventilation

Evidence-Based Practice of Critical Care

Objective data and expert guidance on managing critically ill patients in unique question-based chapters that focus on best practices. Now thoroughly updated by Drs. Clifford S. Deutschman, Patrick J. Neligan, and nearly... read more

Evidence-Based Practice of Critical Care

Cancer Biomarker Measurement using a Smartphone

Canadian researchers create technology that reads cancer biomarker like a blood-sugar monitor. Researchers at the Canadian McMaster and Brock universities have created the prototype for a smartphone device to measure a biomarker... read more

Viscoelastic Hemostatic Assay Augmented Protocols for Major Trauma Hemorrhage

Our international randomized trial has evaluated the role of VHAs to individualize care and augment empiric hemostatic resuscitation in the challenging and time-critical environment of trauma care. Empiric haemostatic therapy... read more

Brain Injury Is More Common in vv-ECMO Than VA-ECMO

Brain injury was more common in venoarterial extracorporeal membrane oxygenation (VA-ECMO) compared with venovenous extracorporeal membrane oxygenation (vv-ECMO). While ischemic brain injury was more common in venoarterial... read more