Resumption of Cardiac Activity after Withdrawal of Life-Sustaining Measures

Resumption of Cardiac Activity after Withdrawal of Life-Sustaining Measures

After withdrawal of life-sustaining measures, transient resumption of at least one cycle of cardiac activity after pulselessness occurred in 14% of patients according to retrospective analysis of waveforms; only 1% of such... read more

Association of Convalescent Plasma Treatment With Clinical Outcomes in Patients With COVID-19

Association of Convalescent Plasma Treatment With Clinical Outcomes in Patients With COVID-19

Treatment with convalescent plasma compared with placebo or standard of care was not significantly associated with a decrease in all-cause mortality or with any benefit for other clinical outcomes. The certainty of the evidence... read more

COVID-19 and VILI: Mechanical Power Measurement

COVID-19 and VILI: Mechanical Power Measurement

The COVID-19 pandemic has increased the need for a bedside tool for lung mechanics assessment and ventilator-induced lung injury (VILI) monitoring. Mechanical power is a unifying concept including all the components which... read more

The Risk of False Negative Results with the Curative COVID-19 Test

The Risk of False Negative Results with the Curative COVID-19 Test

The U.S. Food and Drug Administration (FDA) is alerting patients and health care providers of the risk of false results, particularly false negative results, with the Curative SARS-Cov-2 test. Risks to a patient of a... read more

Estimate Death Probabilities of Hospitalized Patients with COVID-19

Estimate Death Probabilities of Hospitalized Patients with COVID-19

The Covid-19 pandemic has become a global public health crisis and providing optimal patient care while preventing a collapse of the healthcare system is a principal objective worldwide. Here we describe a formula, requiring... read more

Evidence-Based Critical Care

Evidence-Based Critical Care

This is the premier evidence-based textbook in critical care medicine. The Third Edition features updated and revised chapters, numerous new references, streamlined content, and new chapters on key topics such as the new... read more

Mechanical Ventilators for Non-invasive Ventilation

Mechanical Ventilators for Non-invasive Ventilation

This book analyzes and describes the whole spectrum of technical elements related with non-invasive mechanical ventilators technologies, ventilator modes and complementary technologies for correct interpretation and clinical... read more

Evidence-Based Practice of Critical Care

Evidence-Based Practice of Critical Care

Objective data and expert guidance on managing critically ill patients in unique question-based chapters that focus on best practices. Now thoroughly updated by Drs. Clifford S. Deutschman, Patrick J. Neligan, and nearly... read more

Cancer Biomarker Measurement using a Smartphone

Cancer Biomarker Measurement using a Smartphone

Canadian researchers create technology that reads cancer biomarker like a blood-sugar monitor. Researchers at the Canadian McMaster and Brock universities have created the prototype for a smartphone device to measure a biomarker... read more

Viscoelastic Hemostatic Assay Augmented Protocols for Major Trauma Hemorrhage

Our international randomized trial has evaluated the role of VHAs to individualize care and augment empiric hemostatic resuscitation in the challenging and time-critical environment of trauma care. Empiric haemostatic therapy... read more

Brain Injury Is More Common in vv-ECMO Than VA-ECMO

Brain Injury Is More Common in vv-ECMO Than VA-ECMO

Brain injury was more common in venoarterial extracorporeal membrane oxygenation (VA-ECMO) compared with venovenous extracorporeal membrane oxygenation (vv-ECMO). While ischemic brain injury was more common in venoarterial... read more

Pulse Wave Analysis to Estimate Cardiac Output

Pulse Wave Analysis to Estimate Cardiac Output

Cardiac output (CO)–guided therapy is a promising approach to hemodynamic management in high-risk patients having major surgery and in critically ill patients with circulatory shock. Pulmonary artery thermodilution remains... read more

LV Overloading Identified by Critical Care Echocardiography is Key in Weaning‑induced Pulmonary Edema

LV Overloading Identified by Critical Care Echocardiography is Key in Weaning‑induced Pulmonary Edema

Spontaneous breathing trial (SBT) failure due to WIPO appears related to overloaded LV, including the worsening or development of mitral regurgitation, associated with excessive accumulated fluid balance. SBT-induced central... read more

Pragmatic Approach to Inpatient Diabetes Management During COVID-19

Pragmatic Approach to Inpatient Diabetes Management During COVID-19

The pandemic of COVID-19 has presented new challenges to hospital personnel providing care for infected patients with diabetes who represent more than 20% of critically ill patients in ICUs. Appropriate glycemic management... read more