Evolution of Inexpensive Videolaryngoscopy

Evolution of Inexpensive Videolaryngoscopy

Not many procedures in Medicine have received the attention and focus of medical practice, especially in critical care, as laryngoscopy. A secure airway serves as a lifeline to the critically ill, yet the process of securing... read more

Serum Sodium and In-Hospital Mortality in Critically Ill Patients

Serum Sodium and In-Hospital Mortality in Critically Ill Patients

In this large multicenter observational cohort study of ICU patients, we aimed to assess the independent association of changes in serum sodium in the first 48 hours of ICU admission with in-hospital mortality for patients... read more

Mortality and Clinical Characteristics of MIS-C Associated with COVID-19

Mortality and Clinical Characteristics of MIS-C Associated with COVID-19

The clinical presentation and severity of Multisystem Inflammatory Syndrome in Children associated with COVID-19 (MIS-C) is widespread and presents a very low mortality rate in high-income countries. This research describes... read more

Dynamic Delirium Severity Trajectories and Healthcare Utilization

Dynamic Delirium Severity Trajectories and Healthcare Utilization

This secondary analysis did not identify a significant relationship between delirium severity trajectories and healthcare utilization or mortality within 2 years of hospital discharge. The overall sample (n = 431) had... read more

Critical Illness in Patients with Hematologic Malignancy

Critical Illness in Patients with Hematologic Malignancy

Critical illness in patients with a newly diagnosed hematologic malignancy is frequent, occurring early after diagnosis. Certain baseline characteristics can help identify those patients at the highest risk. A total of... read more

COVID-19-related Death in Fully Vaccinated People in Scotland – Characteristics and Risk

COVID-19-related Death in Fully Vaccinated People in Scotland – Characteristics and Risk

Vaccines are highly effective in preventing COVID-19 hospitalisations and deaths. COVID-19-related deaths in fully vaccinated individuals have, however, been reported. To inform public health strategy and vaccination... read more

The Use of Different Sepsis Risk Stratification Tools Uncovers Different Mortality Risks

The Use of Different Sepsis Risk Stratification Tools Uncovers Different Mortality Risks

Our data suggest that the sepsis risk stratification tools currently utilized in emergency departments and on the general wards do not predict mortality adequately. This is illustrated by the disparity in mortality risk... read more

Effect of Moderate vs Mild Therapeutic Hypothermia on Mortality and Neurologic Outcomes in Comatose Survivors of Out-of-Hospital Cardiac Arrest

Effect of Moderate vs Mild Therapeutic Hypothermia on Mortality and Neurologic Outcomes in Comatose Survivors of Out-of-Hospital Cardiac Arrest

In comatose survivors of out-of-hospital cardiac arrest, a target temperature of 31 °C did not significantly reduce the rate of death or poor neurologic outcome at 180 days compared with a target temperature of 34 °C. However,... read more

Time Course of Risk Factors Associated with COVID-19 Mortality

Time Course of Risk Factors Associated with COVID-19 Mortality

The present multicentric study describes 1,260 critically ill patients with COVID-19-associated acute respiratory failure consecutively admitted to 24 Italian ICUs during the first pandemic wave. This study specifically... read more

COVID-19 Surges Increased Patient Mortality

COVID-19 Surges Increased Patient Mortality

A recent study by scientists at the National Institutes of Health suggests that one in every four COVID-19 deaths in the United States may be attributed to hospitals strained by surging caseloads. Published in the Annals... read more

Effects of 5% Albumin Plus Saline vs. Saline Alone on Outcomes From Large-Volume Resuscitation in Critically Ill Patients

Effects of 5% Albumin Plus Saline vs. Saline Alone on Outcomes From Large-Volume Resuscitation in Critically Ill Patients

During large-volume resuscitation, 5% albumin was associated with reduced mortality and major adverse kidney event at 30, 90, and 365 days. However, a higher rate of acute kidney injury of any stage was observed that did... read more

Evolving Changes in Mortality of Critically Ill with COVID-19 Over 8 Months

Evolving Changes in Mortality of Critically Ill with COVID-19 Over 8 Months

Age and mortality rates have declined over the first 8 months of the pandemic. The use of non-invasive respiratory support (NIRS) as the first respiratory support measure was associated with survival, but causal inference... read more

Protecting The Injured RV in COVID-19 ARDS

Protecting The Injured RV in COVID-19 ARDS

The abnormal interaction between the right ventricle (RV) and pulmonary vasculature in various disease states is associated with adverse clinical outcomes. Impaired RV physiology in acute respiratory distress syndrome (ARDS)... read more

Tocilizumab Use May Be Associated with a Short-term Mortality Benefit

Tocilizumab Use May Be Associated with a Short-term Mortality Benefit

For hospitalized COVID-19 patients, there is some evidence that tocilizumab use may be associated with a short-term mortality benefit, but further high-quality data are required. Its benefits may also lie in reducing the... read more