Tag: pneumonia
Non-invasive Respiratory Support and P-SILI in COVID-19
Coronavirus disease 2019 (COVID-19) pneumonia is associated with hypoxemic respiratory failure, ranging from mild to severe. Due to the worldwide shortage of intensive care unit beds, a relatively high number of patients... read more
The Clinical Utility of MRSA Nasal Screening to Rule Out MRSA Pneumonia
Nares screening for methicillin-resistant Staphylococcus aureus (MRSA) had a high specificity and NPV for ruling out MRSA pneumonia, particularly in cases of CAP/HCAP. Based on the NPV, MRSA nares screening is a valuable... read more
POCUS of the Heart and Lungs in Patients with Respiratory Failure
Point-of-care ultrasound (POCUS) is a focus oriented tool for differentiating among cardiopulmonary diseases. Its value in the hands of emergency physicians, with various ultrasound experience, remains uncertain. We tested... read more
Host Endothelial, Epithelial and Inflammatory Response in ICU COVID-19 Patients
These studies demonstrate that, unlike other well-studied causes of critical illness, endothelial dysfunction may not be characteristic of severe COVID-19 early after ICU admission. Pathways resulting in elaboration of acute... read more
Validation of Sputum Gram Stain for Treatment of CAP and HCAP
The usefulness of sputum Gram stain in patients with community-acquired pneumonia (CAP) is controversial. There has been no study to evaluate the diagnostic value of this method in patients with healthcare-associated pneumonia... read more
Post‑COVID‑19 Syndrome in Outpatients
Background Some patients experience long-term symptoms after COVID-19, but data on outpatients with mild-to-moderate COVID-19 are scarce. Objective To describe persisting symptoms more than 3 months after infection in PCR-confirmed... read more
Optimal Needle Position for Decompression of Tension Pneumothorax
Tension Pneumothorax (TP) can occur as a potentially life-threatening complication of chest trauma. With the risk of respiratory and cardiac arrest, an immediate temporizing intervention for this condition is required by... read more
Outcomes of Patients with COVID-19 and Relationship with Lung Ultrasound Signs
In patients with COVID-19 pneumonia, Lung Ultrasound Signs (LUS) signs, including the aeration score, were related to respiratory and systemic symptoms 1 month after ultrasound screening examination. In these patients, a... read more
A Controlled Trial of Methylprednisolone in COVID-19 Pneumonia
The use of corticosteroids in patients with pneumonia secondary to COVID-19 has been a controversially hot topic, particularly early on in the pandemic. Prior evidence seen in Severe Acute Respiratory Syndrome (SARS) and... read more
Virus-Induced Changes of the Respiratory Tract Environment Promote Secondary Infections
Secondary bacterial infections enhance the disease burden of influenza infections substantially. Streptococcus pneumoniae (the pneumococcus) plays a major role in the synergism between bacterial and viral pathogens, which... read more
24-Hour Esophageal pH Measurement in Mechanically Ventilated Children
The current study shows high incidence of gastroesophageal reflux on 24-hour esophageal pH-metry in mechanically ventilated children with medical diagnoses. The significance of this finding and its impact on ventilator-associated... read more
Early Tracheotomy Shortens ICU Stay and Lowers Risk of VAP
Compared with late tracheotomy, early intervention was associated with lower ventilator-associated pneumonia (VAP) rates and shorter durations of mechanical ventilation and ICU stay, but not with reduced short-term, all-cause... read more
Can Ultrasound Predict Histologic Pattern of Lung Injury in COVID‑19 patient?
We have read with great interest the study by de Almeida Monteiro et al. recently published in Intensive Care Medicine, where authors studied the relationship between histopathological data and lung ultrasonographic (LUS)... read more
Endemic COVID-19 Needs Novel, Prognostic Tests to Predict Severity and Progression
COVID-19 has evolved into a long-term population health problem that requires new types of diagnostics. Diagnostic developers, therefore, are called on to expand their developmental focus to include novel tests to predict... read more
Prophylaxis for Pneumocystis Pneumonia in non‐HIV Immunocompromised Patients
Our review shows that TMP/SMX prophylaxis is highly effective for prevention of Prophylaxis for Pneumocystis Pneumonia (PCP) in patients with hematological malignancies, bone marrow transplantation and solid organ transplantation,... read more
Medical oxygen crisis: a belated COVID-19 response
More than a year into the pandemic, global health agencies have set up a taskforce to address the vast unmet demand for medical oxygen. The global pandemic response mechanism, the Access to COVID-19 Tools Accelerator (ACT-A),... read more
Efficacy of Serum Angiotensin II Levels in Prognosis of Patients with COVID-19
The serum angiotensin II levels decrease significantly in patients with coronavirus disease 2019, and this decrease is correlated with lung damage. There was no statistical significance between the serum angiotensin II... read more
Point-of-Care Ultrasound (POCUS) and COVID-19
COVID-19 is a disease caused by infection with SARS-CoV-2, a virus that affects multiple organ systems with numerous disease manifestations. COVID-19 has a specific tropism for the lower respiratory tract, and the most common... read more
No Significant Difference between Tocilizumab and Placebo in Severe COVID-19 Pneumonia Patients
In this randomized trial involving hospitalized patients with severe COVID-19 pneumonia, the use of tocilizumab did not result in significantly better clinical status or lower mortality than placebo at 28 days. In this... read more
Interleukin-6 Receptor Antagonists in Critically Ill Patients with COVID-19
In critically ill patients with COVID-19 receiving organ support in ICUs, treatment with the interleukin-6 receptor antagonists tocilizumab and sarilumab improved outcomes, including survival. Both tocilizumab and sarilumab... read more
