Tag: recovery
Effect of High vs. Low Dose of Dexamethasone on COVID-19 Pneumonia Patients
Among hospitalised COVID-19 patients needing oxygen therapy, high dose of dexamethasone reduced clinical worsening within 11 days after randomisation as compared with low dose of dexamethasone. Further studies are necessary... read more
High-Flow Oxygen Therapy vs. Conventional Oxygen Therapy on Invasive Mechanical Ventilation in COVID-19 Patients
Among patients with severe COVID-19, use of high-flow oxygen through a nasal cannula significantly decreased need for mechanical ventilation support and time to clinical recovery compared with conventional low-flow oxygen... read more
Recovery, Rehabilitation and Follow-up Services After Critical Illness
Overall, these data demonstrate a proliferation of recovery, follow-up and rehabilitation services for critically ill adults in the past decade across the UK, although service gaps remain suggesting further work is required... read more
Higher CRP Rise Not Related To Cytokine Response
The higher C-reactive protein (CRP) rise with late parenteral nutrition (PN), explained by the early macronutrient deficits, did not relate to cytokine responses and thus did not reflect more systemic inflammation. Instead... read more
Optimizing Critical Illness Recovery: Perspectives and Solutions From the Caregivers of ICU Survivors
This qualitative, multicenter, international study of caregivers of critical illness survivors identified consistently unmet needs, means by which caregivers accessed support post ICU, and several care mechanisms identified... read more
Multicomponent Sepsis Transition Effect and Recovery Program After Sepsis
In a multisite randomized clinical trial of patients hospitalized with sepsis, patients provided with a 30-day program using a nurse navigator to provide best practices for postsepsis care experienced a lower proportion of... read more
ARDS vs. PseudoARDS – Failure of the Berlin Definition
True ARDS might be defined as a histological diagnosis involving diffuse alveolar damage throughout the lungs (characterized by hyaline membrane formation and thickening of the alveolar walls). PseudoARDS refers to patients... read more
Changes in Barriers to Implementing Early Mobilization in the ICU
This study was undertaken to investigate the rate of mobilization, defined as a rehabilitation level of sitting on the edge of a bed or higher, and its association with changes in barriers in the intensive care unit (ICU).... read more
Inhaled Budesonide Improves Time to COVID-19 Recovery
Inhaled budesonide improves time to recovery, with a chance of also reducing hospital admissions or deaths (although our results did not meet the superiority threshold), in people with COVID-19 in the community who are at... read more
Should We Prolong the Observation Period for Neurological Recovery After Cardiac Arrest?
Up to 9.6% of cardiac arrest patients with favorable outcomes recover consciousness after the recommended 7 days of observation, indicating the observation time of 7 days seems justified but longer duration may be needed.... read more
RRT in Critically Ill Patients with AKI
Recent evidence has shown that pre-emptive or earlier renal-replacement therapy (RRT) in patients with severe acute kidney injury (AKI) and no urgent indications does not confer clinical benefit. By default, this would imply... read more
Bodily Pain in Survivors of ARDS
Nearly half of acute respiratory distress syndrome (ARDS) survivors reported bodily pain at 6- and 12-month follow-up; one-third reported pain at both time points. Pre-ARDS unemployment, smoking history, and in-ICU opioid... read more
Effect of Neuromuscular Electrical Stimulation on the Recovery of COVID-19 Patients
The rehabilitation of patients with COVID-19 after prolonged treatment in the intensive care unit is often complex and challenging. Patients may develop a myriad of long-term multiorgan impairments, affecting the respiratory,... read more
Discharged IMV COVID-19 Survivors Not Functionally Independent
The majority of invasive mechanical ventilation (IMV) COVID-19 survivors were not functionally independent at discharge and required significant follow-up medical care. The COVID-19 circumstance has placed constraints on... read more
Confirming a Pulse during Resuscitation
Much has been written about using ultrasound in cardiac arrest. The REASON study found that identification of cardiac standstill in PEA or asystole is correlated with almost no chance of meaningful recovery and can assist... read more
Could Physical Therapy Interventions Be Adopted in the Management of Critically Ill Patients with COVID-19?
As part of COVID-19 consequences, it has been estimated that 5% of patients affected by this disease will require admission to the intensive care unit (ICU), and physical therapy techniques have been implemented in patients... read more
NeuroRx Announced Completion of Data Analysis for COVID-19 Treatment Respiratory Failure
NeuroRx, Inc. announced completion of top line data analysis of the 60-day results in its phase 2b/3 clinical trial, conducted under FDA Fast Track Designation, of ZYESAMI™ (aviptadil acetate) for the treatment of critically-ill... read more
Apremilast Not Likely to Reduce Time to Recovery or Mortality in Critically Ill Patients in I-SPY COVID-19 Trial
Quantum Leap Healthcare Collaborative (QLHC), the sponsor of the I-SPY COVID Trial, announced that apremilast (Otezla), made by Amgen, has been dropped for futility. Apremilast was chosen for testing in the I-SPY COVID Trial... read more
Effect of a Single High Dose of Vitamin D3 on Hospital LOS in Patients with COVID-19
Among hospitalized patients with COVID-19, a single high dose of vitamin D3, compared with placebo, did not significantly reduce hospital length of stay. The findings do not support the use of a high dose of vitamin D3 for... read more
Consequences of COVID-19 in discharged patients
At 6 months after acute infection, COVID-19 survivors were mainly troubled with fatigue or muscle weakness, sleep difficulties, and anxiety or depression. Patients who were more severely ill during their hospital stay... read more
Meralgia Paresthetica: COVID-19-associated ARDS treated with prone positioning
Prone positioning is one of the few interventions in acute respiratory distress syndrome (ARDS) which has a proven mortality reduction. Due to the coronavirus disease 2019 (COVID-19) pandemic, severe ARDS cases have sharply... read more
Tocilizumorelikeit? The latest data on Tocilizumab
Our hats were then blown away when the REMAP-CAP team and the UK government fired an evidence-based carpet bomb in our direction. We saw a trial press release, a preprint article, an alert letter from the MHRA/DHSC, national... read more
