Effect of a Single High Dose of Vitamin D3 on Hospital LOS in Patients with COVID-19

Effect of a Single High Dose of Vitamin D3 on Hospital LOS in Patients with COVID-19

Among hospitalized patients with COVID-19, a single high dose of vitamin D3, compared with placebo, did not significantly reduce hospital length of stay. The findings do not support the use of a high dose of vitamin D3 for... read more

Consequences of COVID-19 in discharged patients

Consequences of COVID-19 in discharged patients

At 6 months after acute infection, COVID-19 survivors were mainly troubled with fatigue or muscle weakness, sleep difficulties, and anxiety or depression. Patients who were more severely ill during their hospital stay... read more

Meralgia Paresthetica: COVID-19-associated ARDS treated with prone positioning

Meralgia Paresthetica: COVID-19-associated ARDS treated with prone positioning

Prone positioning is one of the few interventions in acute respiratory distress syndrome (ARDS) which has a proven mortality reduction. Due to the coronavirus disease 2019 (COVID-19) pandemic, severe ARDS cases have sharply... read more

Tocilizumorelikeit? The latest data on Tocilizumab

Tocilizumorelikeit? The latest data on Tocilizumab

Our hats were then blown away when the REMAP-CAP team and the UK government fired an evidence-based carpet bomb in our direction. We saw a trial press release, a preprint article, an alert letter from the MHRA/DHSC, national... read more

Artificial Intelligence in Telemetry: What Clinicians Should Know

Artificial Intelligence in Telemetry: What Clinicians Should Know

Advances in artificial intelligence are beginning to unlock the potential of telemetry data to directly inform diagnosis and personalized treatment. We can see hints of this in considering the case above. Is a second... read more

Venoarterial ECMO in Elderly Patients with Refractory Cardiogenic Shock

Venoarterial ECMO in Elderly Patients with Refractory Cardiogenic Shock

The clinical utilization of extracorporeal membrane oxygenation (ECMO) has seen remarkable expansion since its inception in the early 1970s, including a period of exponential growth in the United States. Venoarterial... read more

Caring for the Sickest COVID-19 Patients: An ICU Story

Caring for the Sickest COVID-19 Patients: An ICU Story

In an article for the latest issue of Stanford Medicine magazine, I provide a glimpse into the journey Free and his front-line Stanford Health Care colleagues took -- from Day 1 through the following weeks and months -- to... read more

Artificial Neural Networks Improve Prediction and Risk Classification in ICU Patients

Artificial Neural Networks Improve Prediction and Risk Classification in ICU Patients

A supervised machine learning model using artificial neural networks (ANN) predicted neurological recovery, including survival excellently, and outperformed a conventional model based on logistic regression. Among the data... read more

Turn the Lights On!: A Physician’s Personal Journey from the Darkness of Traumatic Brain Injury (TBI) to Hope, Healing, and Recovery

Turn the Lights On!: A Physician’s Personal Journey from the Darkness of Traumatic Brain Injury (TBI) to Hope, Healing, and Recovery

Often misdiagnosed and misunderstood, traumatic brain injury (TBI) may be a life-altering event which can produce a wide range of symptoms affecting physical as well as psychological health. Indeed, all senses can be affected,... read more

Massive PE with Intra-hospital Cardiac Arrest and Full Recovery of RV Function after vaECMO

Massive PE with Intra-hospital Cardiac Arrest and Full Recovery of RV Function after vaECMO

The concept of vaECMO treatment alone might be a valuable alternative in selected patients with massive PE and cardiogenic shock, in whom thrombolytic therapy might not unload the RV fast enough. We present a case of a... read more

COVID-19: How to Quantify and Interpret Treatment Effects in Comparative Clinical Studies

COVID-19: How to Quantify and Interpret Treatment Effects in Comparative Clinical Studies

Clinical trials of treatments for coronavirus disease 2019 (COVID-19) draw intense public attention. More than ever, valid, transparent, and intuitive summaries of the treatment effects, including efficacy and harm, are needed.... read more

Lenzilumab Showed Rapid Clinical Improvement in 12 COVID-19 Patients

Lenzilumab Showed Rapid Clinical Improvement in 12 COVID-19 Patients

Humanigen, the clinical stage biopharmaceutical company focused on preventing and treating cytokine storm, has reported positive data from the first clinical use of lenzilumab, its humaneered anti-human granulocyte macrophage-colony... read more

Innovative Approaches to Patient Rehabilitation Maximize COVID-19 Recovery

Innovative Approaches to Patient Rehabilitation Maximize COVID-19 Recovery

People hospitalized with COVID-19 can experience debilitating physical changes — extreme fatigue, difficulty breathing and muscle weakness, says April Pruski, M.D., a Johns Hopkins physiatrist (a medical doctor who specializes... read more

COVID-19 Patients with ARDS Face Significant Financial Effects in Recovery

COVID-19 Patients with ARDS Face Significant Financial Effects in Recovery

Long hospitalizations lead to large medical bills, with serious physical and emotional consequences for those recovering from critical illness. It begins with shortness of breath. And for approximately one-third of patients,... read more