Venoarterial ECMO in Elderly Patients with Refractory Cardiogenic Shock

Venoarterial ECMO in Elderly Patients with Refractory Cardiogenic Shock

The clinical utilization of extracorporeal membrane oxygenation (ECMO) has seen remarkable expansion since its inception in the early 1970s, including a period of exponential growth in the United States. Venoarterial... read more

Caring for the Sickest COVID-19 Patients: An ICU Story

Caring for the Sickest COVID-19 Patients: An ICU Story

In an article for the latest issue of Stanford Medicine magazine, I provide a glimpse into the journey Free and his front-line Stanford Health Care colleagues took -- from Day 1 through the following weeks and months -- to... read more

Artificial Neural Networks Improve Prediction and Risk Classification in ICU Patients

Artificial Neural Networks Improve Prediction and Risk Classification in ICU Patients

A supervised machine learning model using artificial neural networks (ANN) predicted neurological recovery, including survival excellently, and outperformed a conventional model based on logistic regression. Among the data... read more

Turn the Lights On!: A Physician’s Personal Journey from the Darkness of Traumatic Brain Injury (TBI) to Hope, Healing, and Recovery

Turn the Lights On!: A Physician’s Personal Journey from the Darkness of Traumatic Brain Injury (TBI) to Hope, Healing, and Recovery

Often misdiagnosed and misunderstood, traumatic brain injury (TBI) may be a life-altering event which can produce a wide range of symptoms affecting physical as well as psychological health. Indeed, all senses can be affected,... read more

Massive PE with Intra-hospital Cardiac Arrest and Full Recovery of RV Function after vaECMO

Massive PE with Intra-hospital Cardiac Arrest and Full Recovery of RV Function after vaECMO

The concept of vaECMO treatment alone might be a valuable alternative in selected patients with massive PE and cardiogenic shock, in whom thrombolytic therapy might not unload the RV fast enough. We present a case of a... read more

COVID-19: How to Quantify and Interpret Treatment Effects in Comparative Clinical Studies

COVID-19: How to Quantify and Interpret Treatment Effects in Comparative Clinical Studies

Clinical trials of treatments for coronavirus disease 2019 (COVID-19) draw intense public attention. More than ever, valid, transparent, and intuitive summaries of the treatment effects, including efficacy and harm, are needed.... read more

Lenzilumab Showed Rapid Clinical Improvement in 12 COVID-19 Patients

Lenzilumab Showed Rapid Clinical Improvement in 12 COVID-19 Patients

Humanigen, the clinical stage biopharmaceutical company focused on preventing and treating cytokine storm, has reported positive data from the first clinical use of lenzilumab, its humaneered anti-human granulocyte macrophage-colony... read more

Innovative Approaches to Patient Rehabilitation Maximize COVID-19 Recovery

Innovative Approaches to Patient Rehabilitation Maximize COVID-19 Recovery

People hospitalized with COVID-19 can experience debilitating physical changes — extreme fatigue, difficulty breathing and muscle weakness, says April Pruski, M.D., a Johns Hopkins physiatrist (a medical doctor who specializes... read more

COVID-19 Patients with ARDS Face Significant Financial Effects in Recovery

COVID-19 Patients with ARDS Face Significant Financial Effects in Recovery

Long hospitalizations lead to large medical bills, with serious physical and emotional consequences for those recovering from critical illness. It begins with shortness of breath. And for approximately one-third of patients,... read more

Recovering from COVID-19: Post Viral-fatigue and Conserving Energy

Recovering from COVID-19: Post Viral-fatigue and Conserving Energy

Rehabilitation is fast becoming the new priority in dealing with the impact of this pandemic and is crucial for people recovering from COVID-19 infection. Royal College of Occupational Therapists published three guides... read more

Humanizing the ICU Experience with Enhanced Communication

Humanizing the ICU Experience with Enhanced Communication

Decisions to limit therapy (DTLT) are routine for ICU physicians. Although breaking bad news is one of the most difficult tasks clinicians face, ongoing communication is even more crucial as families (not necessary following... read more

Impact of Protocolized Diuresis for De-resuscitation in the ICU

Impact of Protocolized Diuresis for De-resuscitation in the ICU

Using a diuresis protocol for volume de-resuscitation, we demonstrated a significant decrease in net cumulative fluid balance at 72 h following shock resolution, with potential benefit on clinical outcomes including renal... read more

Standardized EEG Analysis to Reduce the Uncertainty of Outcome Prognostication After Cardiac Arrest

Standardized EEG Analysis to Reduce the Uncertainty of Outcome Prognostication After Cardiac Arrest

In the majority of comatose cardiac arrest (CA) patients, the outcome remains indeterminate after application of ERC/ESICM prognostication algorithm. Standardized EEG background analysis enables accurate prediction of both... read more

When Exercise Comes to the Hospital’s ICUs

When Exercise Comes to the Hospital’s ICUs

Even short hospital ICU stays can cause lasting problems for patients. Can early mobility and exercise help? Apna Kudchadkar still remembers the morning in 2010 that shaped the trajectory of her scientific research. She... read more

Automated Anesthetic Management Outperforms Manual Control and May Have an Impact on Delayed Neurocognitive Recovery

Automated Anesthetic Management Outperforms Manual Control and May Have an Impact on Delayed Neurocognitive Recovery

Among older, non-frail patients undergoing moderate and high-risk noncardiac surgery, an automated anesthetic management using the combination of three independent closed-loop systems outperformed manual control and may have... read more

Prognostic Value of Spreading Depolarizations in Patients With Severe TBI

Prognostic Value of Spreading Depolarizations in Patients With Severe TBI

In this cohort study of patients with acute brain trauma, spreading depolarizations were predominant but heterogeneous and independently associated with poor neurologic recovery. Monitoring the occurrence of spreading depolarizations... read more

Tailoring Nutrition Therapy to Illness and Recovery

Tailoring Nutrition Therapy to Illness and Recovery

Without doubt, in medicine as in life, one size does not fit all. We do not administer the same drug or dose to every patient at all times, so why then would we live under the illusion that we should give the same nutrition... read more