Tag: research
How and When to End the COVID-19 Lockdown
Countries around the world are in a state of lockdown to help limit the spread of SARS-CoV-2. However, as the number of new daily confirmed cases begins to decrease, governments must decide how to release their populations... read more
COVID-19: 10 Things I Wished I’d Known Some Months Ago
The COVID-19 pandemic is ongoing and spreading, affecting individuals in over 200 countries now. While COVID-19-related articles are being published every day, including guidelines of optimal clinical management, there are... read more
COVID-19 Patients with ARDS Face Significant Financial Effects in Recovery
Long hospitalizations lead to large medical bills, with serious physical and emotional consequences for those recovering from critical illness. It begins with shortness of breath. And for approximately one-third of patients,... read more
Are Phenotypes a Magic Bullet for Sepsis?
There's a constant battle in medicine between practice styles—standardization and customization. Standardization is order sets and doing the same thing for every patient every time because it (hopefully) delivers better... read more
Corticosteroids for Critically Ill COVID-19 Patients with Cytokine Release Syndrome
Approximately 5% of coronavirus disease (COVID-19) patients will require admission to an intensive care unit (ICU). Among these patients, the most severe cases may be mediated by a late-onset systemic inflammatory response... read more
Implantation of Impella CP LV Assist Device Under the Guidance of 3D Intracardiac Echocardiography
This translational study in ovine model confirms that three-dimensional intracardiac echocardiography is a feasible option to guide implantation of the Impella CP® for left ventricular mechanical support and should be considered... read more
Blood Thinners May Improve Survival Among Hospitalized COVID-19 Patients
Treating hospitalized COVID-19 patients with anticoagulants--blood thinners that slow down clotting--may improve their chances of survival, researchers from the Mount Sinai COVID Informatics Center report. The study,... read more
50 Studies Every Intensivist Should Know
50 Studies Every Intensivist Should Know presents key studies that have shaped the practice of critical care medicine. Selected using a rigorous methodology, the studies cover topics including: sedation and analgesia, resuscitation,... read more
On the Front Lines in Fight Against COVID-19
As a worldwide pandemic washes over the St. Louis region, the Washington University Medical Campus is eerily quiet. Most visitors, students, staff and research faculty are no longer on campus. Limited patients come to its... read more
Pandemic Science Out of Control
A toxic legacy of poor-quality research, media hype, lax regulatory oversight, and vicious partisanship has come home to roost in the search for effective treatments for COVID-19. The rush to offer unproven treatments... read more
COVID-19 and Critical Care
In this podcast, we talk about the clinical journey of a COVID-19 patient and some insights from the critical care unit. There are some concepts here that we probably don't do full justice to in the time we had, so here are... read more
Comparison of Echocardiographic and Invasive Measures of Volaemia and Cardiac Performance in Critically Ill Patients
Static echocardiographic variables did not reliably reflect the volume state as defined by estimates of mean systemic filling pressure. There was no statistical or clinically robust relationship between static echocardiographic... read more
Yale study finds self-isolation would dramatically reduce ICU bed demand
As soon as Alison Galvani learned of the COVID-19 virus in China and its devastating spread there, she foresaw what might happen to healthcare facilities in the United States. The Yale professor and colleagues at the... read more
BCG Vaccination Might Protect Healthcare Workers Against COVID-19
Australian and European researchers are testing if the Bacille Calmette-Guerin (BCG) vaccine, introduced in the 1920s to fight tuberculosis, will be deployed to combat COVID-19, the respiratory disease caused by the novel... read more
