Tag: research
Sepsis: Definitions, Pathophysiology and the Challenge of Bedside Management
A comprehensive and state-of-the-art resource for clinicians who care for patients with sepsis and research scientist alike. Patients with severe sepsis requiring ICU admission have very high rates of ICU and overall... read more
Handbook of Lung Targeted Drug Delivery Systems: Recent Trends and Clinical Evidences
Handbook of Lung Targeted Drug Delivery Systems: Recent Trends and Clinical Evidences covers every aspect of the drug delivery to lungs, the physiology and pharmacology of the lung, modelling for lung delivery, drug devices... read more
Clinical Outcomes in Critically Ill COVID-19 Unvaccinated Patients Admitted to the ICU
We analyzed unvaccinated critically ill ICU patients with COVID-19 and interpreted their demographics, clinical characteristics, comorbidities, and laboratory data upon ICU admission for a better understanding of their impact... read more
10 Reasons for Pharmacy Professionals Presence in the ICU
The momentum exists for establishing and expanding ICU pharmacy practice throughout Europe. A first step should be a White Paper, describing the roles and key priorities for ICU pharmacy professionals. Education should... read more
Screening Tools for Sepsis Identification
The authors undertook a rapid review to determine the suitability of sepsis screening tools in the emergency setting with regard to sensitivity and specificity of sepsis diagnosis. The review recognized that there is currently... read more
Acute Undifferentiated Fever with Thrombocytopenia: Clinical and Etiological Profile
Prompt recognition and management of thrombocytopenia in acute undifferentiated fever are vital. Thrombocytopenia, along with organ dysfunction and shock, significantly influence patient outcomes. Tailored interventions based... read more
Sepsis Prediction Model for Determining Sepsis vs. SIRS, qSOFA, and SOFA
In this cohort study of 60,507 hospital admissions, we found that although the SPM marginally outperformed existing prediction scores in balanced accuracy for classification of sepsis, it suffers from poor timeliness, limiting... read more
Ground-breaking New AI Technology for Severe Sepsis Rapid Identification
ASEP Medical Holdings Inc. announced the ground-breaking use of artificial intelligence (AI) to rapidly identify infections at increased risk of severe sepsis. The method was developed by the Hancock Lab, under the guidance... read more
Biomarkers in Trauma, Injury and Critical Care (Biomarkers in Disease: Methods, Discoveries and Applications)
This handbook systematically presents biomarkers for traumatic injuries. The book covers topics such as traumatic brain injury, liver injury, burn severity, muscle heart damage, and acute inflammation in polytrauma and their... read more
Noninvasive Mechanical Ventilation: Theory, Equipment, and Clinical Applications
The new edition presents updates regarding new clinical applications of noninvasive mechanical ventilation and discusses recent technical advances in this field. The opening sections are devoted to theory, equipment, with... read more
Oxford Textbook of Critical Care
The thoroughly revised 2nd edition of the Oxford Textbook of Critical Care is a comprehensive multi-disciplinary text covering all aspects of adult intensive care management. Uniquely the book takes a problem-orientated approach... read more
Secondary Bacterial Pneumonia is the Key Factor in COVID-19 Fatalities Not Cytokine Storm
A recent study found that secondary bacterial pneumonia, rather than the much-discussed “cytokine storm,” is a significant factor in COVID-19-related fatalities. Almost half of the patients who required mechanical... read more
Effect of P2Y12 Inhibitors on Organ Support-Free Survival in COVID-19 Patients
n this randomized clinical trial of critically ill participants hospitalized for COVID-19, treatment with a P2Y12 inhibitor did not improve the number of days alive and free of cardiovascular or respiratory organ support.... read more
Diastolic Shock Index and Septic Shock Outcome
Early recognition and resuscitation of patients in septic shock are critical skills for an emergency medicine physician. Many clinical decision-making tools have been developed and validated in their use to identify and... read more
Advances in Microbiology, Infectious Diseases and Public Health: Volume 15
This book series focuses on current progress in the broad field of medical microbiology, and covers both basic and applied topics related to the study of microbes, their interactions with human and animals, and emerging issues... read more
Methylene Blue Reduced Length of Stay in ICU
In patients with septic shock, methylene blue (MB) initiated within 24 h reduced time to vasopressor discontinuation and increased vasopressor-free days at 28 days. It also reduced length of stay in ICU and hospital without... read more
Acute Lung Injury and Repair: Scientific Fundamentals and Methods
Acute Respiratory Distress Syndrome (ARDS) remains an important cause of morbidity and mortality worldwide, and the incidence is predicted to increase with the aging population. Several clinical disorders can initiate... read more
