Genomics, Health Disparities, and Missed Opportunities for the Nation’s Research Agenda

The completion of the Human Genome Project occurred at a time of increasing public attention to health disparities. In 2004, Sankar and colleagues1 suggested that this coincidental timing resulted in an inappropriate emphasis... read more

Data Authorship as an Incentive to Data Sharing

Data from well-designed and well-executed research not only are useful for the original purpose and secondary analyses by the original researchers but also can be repurposed for a variety of applications, including independent... read more

Rules of thumb for writing research articles

The paper provides 'rules of thumb' for writing research articles (RA) and getting them published. These were discussed during the "Scientific writing course" organized for ITC PhD students by Cressie... read more

Vitamin C and the Ethics of Borrowing data

I was recently amazed to be engaged in a Twitter kerfuffle which generated more than 10,000 Impressions within 24 hours. Passions were running high, libellous comments were being broadcast, and old friendships seemed to be... read more

The Case for Removing Barriers to APRN Practice

The IOM issued The Future of Nursing: Leading Change, Advancing Health, which called for the removal of laws, regulations and policies that prevent APRNs from providing the full scope of health care services they are educated... read more

Predicting and measuring fluid responsiveness with echocardiography

Echocardiography is an essential tool to predict and measure fluid responsiveness, according to a recent article, which provides a practical guide. Ashley Miller and Justin Mandeville outline the physiological basis of fluid... read more

Doctor Turns Up Possible Treatment For Deadly Sepsis

It is hard not to get excited about news of a potentially effective treatment for sepsis, a condition that leads to multiple organ failure and kills more people in the hospital than any other disease. The study, from Eastern... read more

Management of COPD exacerbations: a European Respiratory Society/American Thoracic Society guideline

This document provides clinical recommendations for treatment of chronic obstructive pulmonary disease (COPD) exacerbation. This recommendation places a high value on improving clinical outcomes and a lower value on the burden... read more

Milestones in Critical Care

Take a look back at some of Critical Care's milestones over the past 20 years. In the past 20 years, the journal has contributed to improving the care of critically ill patients by acquiring, discussing, distributing... read more

New AAMC Research Reaffirms Looming Physician Shortage

The United States will face a shortage of between 40,800 and 104,900 physicians by 2030, according to a new study commissioned by the AAMC. Released March 14, 2017, the study found that the numbers of new primary care physicians... read more

Moderate Exercise and Oxygen Consumption in Hypertrophic Cardiomyopathy

This randomized clinical trial assesses whether moderate-intensity exercise training, compared with usual activity, improves exercise capacity in adults with hypertrophic cardiomyopathy. During a 5-year period, 728 adult... read more

The ICM research agenda on ICU-acquired weakness

Intensive care unit (ICU)-acquired weakness (ICUAW) develops as a complication of critical illness and may represent the extreme end of a spectrum of weakness that begins with any serious illness regardless of care location.... read more

Vasopressors: Future Research

Margaret Parker, MD, MCCM, speaks with Lakhmir S. Chawla, MD, about future research related to the Congress session "Bench-Pressing in the ICU: Which Vasopressor Agent Should I Choose for My Patient?" which he presented... read more

Funding for NIH Would Be Cut 18% Under Budget

Funding for the National Institutes of Health, the nation’s premier medical research funding agency, would be cut by 18%, or $5.8 billion, from levels enacted for fiscal 2017, under the Trump administration budget.... read more

The Toll of Death and Disability From Traumatic Injury in the United States

This viewpoint describes the lack of funding for trauma research as a possible cause of increasing mortality rates from traumatic injury. In a seminal 1966 report, the National Research Council (NRC) declared that unintentional... read more

Decision Making Model Enables Resolution of Ethics Issues at the Bedside

A study from Switzerland that evaluated implementation of a stepped ethical decision-making model on three intensive care units (ICUs) and two geriatric wards found that it worked well, with staff able to find the time and... read more

Ratio-based Transfusion and Non-trauma Patients

Researchers at Massachusetts General Hospital (MGH) urge caution in adopting ratio-based transfusion - a practice previously studied only in patients with severe traumatic injuries - in non-trauma patients. Their study published... read more

Visual Abstracts, A New Strategy for Creating Journal Articles

You might be interested in this initiative arising out of surgery, and primarily developed by Andrew M. Ibrahim MD, MSc of the University of Michigan. Dr. Ibrahim is a Clinical Lecturer in Surgery here and a Robert Wood Johnson... read more

No IV Hydration for Contrast Nephropathy? AMACING Trial Challenges a Cornerstone of Prophylaxis

A Dutch study undercutting the established role of hydration in preventing kidney damage during procedures is raising eyebrows. Dutch researchers are calling into question one of the cornerstone practices of cath labs and... read more

Longer hospital stays may reduce readmissions, study suggests

A recent study found patients moved to post-acute care facilities have a higher chance of readmission than those kept in the hospital for a longer period of time. Researchers say longer hospital stays may prevent readmission... read more

In Hospital ICUs, AI Could Predict Which Patients Are Likely to Die

With streams of data coming from equipment that monitors patients’ vital signs, the ICU seems the perfect setting to deploy artificially intelligent tools that could judge when a patient is likely to take a turn for the... read more

Stapled versus hand-sewn

Stapled versus hand-sewn: A prospective emergency surgery study. An American Association for the Surgery of Trauma multi-institutional study. Data from the trauma patient population suggests handsewn (HS) anastomoses are... read more