Neuro ICU Early Mobilization Protocol

Researchers in the U.S. have developed a multidisciplinary Neuro Early Mobilization Protocol for complex patients in the neuroscience intensive care unit (NSICU). Developing an evidence-based protocol with inter-professional... read more

Burnout Syndrome in Critical Care: A Call for Action

Burnout syndrome (BOS) is a work-related constellation of symptoms and signs that usually occurs in individuals with no history of psychological or psychiatric disorders. BOS is triggered by a discrepancy between the expectations... read more

Clinical Practice Guideline: Mechanical Ventilation in Adult Patients with ARDS

An Official American Thoracic Society/European Society of Intensive Care Medicine/Society of Critical Care Medicine Clinical Practice Guideline: Mechanical Ventilation in Adult Patients with Acute Respiratory Distress Syndrome.... read more

Hospitalists can help improve antibiotic stewardship

Hospitalists can, and should, help curb unnecessary antibiotic use. Nearly three-quarters of patients who have been diagnosed with community acquired pneumonia are receiving antibiotics for longer periods than necessary,... read more

We're Bad at Death. Can We Talk?

Despite growing recognition that more care isn't necessarily better care, particularly at the end of life, many Americans still receive an enormous dose of medicine in their final days. On average, patients make 29 visits... read more

Reduction In Blood Gas Time To Result In ICU

A recent time and motion study by University Hospital Southampton NHS Foundation Trust has demonstrated a 1.5 minute (>20%) reduction in time to blood gas results when using the Proxima bedside blood gas monitoring system... read more

PTSD, Psychotropic Medication Use, and the Risk of Dementia Among US Veterans

Objective: To determine the associations between PTSD, psychotropic medication use, and the risk for dementia. PTSD diagnosis significantly increased the risk for dementia diagnosis (HR = 1.35; [95% CI = 1.27–1.43]). However,... read more

A Breakthrough Oxygen Therapy May Be Able to Reverse Brain Damage

New research shows that low oxygen therapy is able to eliminate brain lesions developed from mitochondrial dysfunction in mice. Eventually, hypoxia therapy could be used to treat people with similar disorders and maybe even... read more

Why digital disruption is only starting in healthcare

Disruption often is viewed as a positive noun in the business world. Particularly in healthcare, such disruption can result in increased understanding and enhanced outcomes, among other benefits. Healthcare has clearly... read more

CDC and Prevention Guideline for the Prevention of Surgical Site Infection

This guideline is intended to provide new and updated evidence-based recommendations for the prevention of SSI and should be incorporated into comprehensive surgical quality improvement programs to improve patient safety.... read more

Facing Change: When to Embrace, When to Resist

This editorial is focused on 3 major areas where change is occurring: (1) change in scientific evidence leading to modification in practice, (2) changes in the health care system structure and how it affects our daily lives,... read more

MRI in Pulmonary Embolism Diagnosis

Magnetic resonance imaging (MRI) has high specificity but limited sensitivity for the diagnosis of pulmonary embolism (PE), according to a systematic review published in the journal Thrombosis Research. Given these inconclusive... read more

Why Does Conflict of Interest Matter?

In this Viewpoint, the former president of the Institute of Medicine discusses the importance of conflicts of interest to the integrity of the medical profession, and the importance of policies to manage conflicts of interest... read more

New Ways for Research Findings to Reach More People

When it comes to sharing new research findings with the world, Twitter has emerged as a key tool for scientists - and for the journals where they publish their findings. But a new study shows a way for that research to reach... read more

New Study: Economic Cost to Surviving ARDS

Research published today in the American Journal of Respiratory and Critical Care Medicine sheds light on the economic toll on survivors of acute respiratory distress syndrome. Nearly 50% of survivors who worked before they... read more

Identifying barriers to delivering the ABCDE bundle to minimize adverse outcomes for mechanically ventilated patients

Improved outcomes are associated with the Awakening, Breathing Coordination, Delirium and Early mobility/exercise (ABCDE) bundle; however, implementation issues are common. As yet, no study has integrated the barriers to... read more

Micro-Hospitals Provide Health Care Closer to Home

Small-scale inpatient facilities, known in the industry as micro-hospitals, are popping up across the country to offer medical care in underserved communities and provide provide a local alternative to the potentially long... read more

Single IRBs in Multisite Trials

On June 21, 2016, the US government announced changes that are arguably the most significant of the last quarter century concerning the protection of human research participants - a requirement for use of central or single... read more

NIH Consortium to Study Biomarkers for Dementia

A new National Institutes of Health (NIH) funded consortium will work to identify and validate trial-ready biomarkers for small vessel diseases in the brain that contribute to cognitive impairment and dementia. Seven participating... read more

The impact of oral care on oral health status and prevention of VAP in critically ill patients

Ventilator-associated pneumonia (VAP) is one of the most common nosocomial infections which increase mortality rate and length stay of hospitalization. Oral care would not only improve patient’s oral health and well-being,... read more

Big Data Detects Sepsis In Major Hospitals

Data analytics have found that large medical facilities have higher rates of death from sepsis than their smaller hospital counterparts. Researchers from Houston Methodist Hospital recently used Big Data analytics to learn... read more

Fluid resuscitation in human sepsis: Time to rewrite history

Fluid resuscitation continues to be recommended as the first-line resuscitative therapy for all patients with severe sepsis and septic shock. The current acceptance of the therapy is based in part on long history and familiarity... read more